scholarly journals Distribution and determinants of coronary artery calcium score in asymptomatic patients with diabetes in two different settings: Comparison between patients in continental France and La Reunion Island

2022 ◽  
Vol 14 (1) ◽  
pp. 13
Author(s):  
M. Sow ◽  
Y. Mutunzi ◽  
J. Magne ◽  
E. Nobecourt ◽  
V. Aboyans
2018 ◽  
Vol 15 (6) ◽  
pp. 519-527 ◽  
Author(s):  
Hadii M Mamudu ◽  
Arsham Alamian ◽  
Timir Paul ◽  
Pooja Subedi ◽  
Liang Wang ◽  
...  

Aim: To examine the association of cardiovascular disease risk factors with and their cumulative effect on coronary artery calcium in hard-to-reach asymptomatic patients with diabetes. Methods: A total of 2563 community-dwelling asymptomatic subjects from Central Appalachia participated in coronary artery calcium screening at a heart centre. Binary variable was used to indicate that coronary artery calcium was either present or absent. Independent variables consisted of demographic and modifiable risk factors and medical conditions. Descriptive statistics and multinomial logistic regression analyses were conducted. Results: In total, 55.8% and 13.7% of study participants had subclinical atherosclerosis (coronary artery calcium ⩾1) and diabetes, respectively. The presence of coronary artery calcium was higher in subjects with diabetes (68.5%) than those without (53.8%). Compared to subjects without diabetes with coronary artery calcium = 0, obesity, hypertension, hypercholesterolaemia and smoking increased the odds of the presence of coronary artery calcium (coronary artery calcium score ⩾1) regardless of diabetes status; however, with larger odds ratios in subjects with diabetes. Compared to subjects without diabetes with coronary artery calcium score = 0, having 3, 4 and ⩾5 risk factors increased the odds of presence of coronary artery calcium in subjects with diabetes by 14.06 (confidence interval = 3.26–62.69), 32.30 (confidence interval = 7.41–140.82) and 47.12 (confidence interval = 10.35–214.66) times, respectively. Conclusion: There is a need for awareness about subclinical atherosclerosis in patients with diabetes and more research about coronary artery calcium in subpopulations of patients.


2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Vishesh Kumar ◽  
Shawn Kelly ◽  
Amol Raizada ◽  
Amornpol Anuwatworn ◽  
Jimmy Yee ◽  
...  

Background: Elevated calcium score is a marker of increased risk in the development of cardiovascular and cerebrovascular disease. It is unknown whether an elevated coronary artery calcium score is associated with extravascular calcium deposition in disease states such as nephrolithiasis and cholelithiasis. The aim of this study was to explore this relationship in asymptomatic patients who had elective coronary calcium scoring performed at the University of South Dakota Sanford Medical Center. Methods: We performed a retrospective review of data from 38,546 consecutive patients from the coronary calcium screening database. Patients with a history of calculi were identified using ICD-9 codes for calculus of kidney and ureter (592) and cholelithiasis (574). Cases were analyzed according to gender and age groups, and proportions calculated according to calcium score tertile. Results: The results are summarized in Table 1. Overall, the proportion of patients with calculi increases with each rise in the coronary artery calcium score. However, this relationship is best demonstrated in the elderly male and younger female populations. This relationship was further analyzed using a chi-square contrast test. The results, as described in Table 2, indicate that there is a significant relationship between elevated coronary calcium and likelihood of calculi conditions in young females (p=0.0040), however, the proportion in elderly males does not exhibit a statistical difference in proportion (p=0.1143). Conclusion: Elevated coronary artery calcium is associated with an increased likelihood of having a diagnosis of extravascular calculi development such as nephrolithiasis or cholelithiasis. Younger females appear to best demonstrate this relationship. Although the proportions are small, further studies are needed to substantiate a biochemical basis for this relationship.


2017 ◽  
Vol 50 (3) ◽  
pp. 182-189 ◽  
Author(s):  
Priscilla Ornellas Neves ◽  
Joalbo Andrade ◽  
Henry Monção

Abstract The coronary artery calcium score plays an Important role In cardiovascular risk stratification, showing a significant association with the medium- or long-term occurrence of major cardiovascular events. Here, we discuss the following: protocols for the acquisition and quantification of the coronary artery calcium score by multidetector computed tomography; the role of the coronary artery calcium score in coronary risk stratification and its comparison with other clinical scores; its indications, interpretation, and prognosis in asymptomatic patients; and its use in patients who are symptomatic or have diabetes.


2012 ◽  
Vol 18 (2) ◽  
pp. 122-129
Author(s):  
Ryouko Kinoshita ◽  
Eriko Matsunaga ◽  
Yuji Nishizaki ◽  
Takayuki Yokoyama ◽  
Seigo Itou ◽  
...  

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