483: Correlates of urinary arsenic metabolites in women of childbearing age in the national health and nutrition examination survey (NHANES) 2000-2010

2015 ◽  
Vol 212 (1) ◽  
pp. S245
Author(s):  
Jennifer Peng ◽  
Paul Sobolewski ◽  
Barbara Strong ◽  
Anthea Paul ◽  
Judith Boura ◽  
...  
2012 ◽  
Vol 15 (7) ◽  
pp. 1216-1227 ◽  
Author(s):  
Sarah C Tinker ◽  
Mary E Cogswell ◽  
Heather C Hamner ◽  
Robert J Berry

AbstractObjectiveThe USA currently fortifies enriched cereal grain products (ECGP) with folic acid at 140 μg/100 g. In addition, folic acid can be voluntarily added to ready-to-eat cereals (RTEC) up to 400 μg/serving and it is found in many dietary supplements, most often at a dose of 400 μg. We sought to model folic acid intake under various fortification and supplementation scenarios.DesignThe National Health and Nutrition Examination Survey is a population-based cross-sectional survey representative of the non-institutionalized, civilian US population. Information on folic acid intake is collected in two 24 h dietary recalls and survey questions on dietary supplement use, which allows estimation of usual total folic acid intake. We modelled five different levels of folic acid fortification in ECGP, while varying the amounts in RTEC and dietary supplements.SettingUnited States.SubjectsUS adults (n 14 353) aged ≥19 years; non-pregnant women of childbearing age (n 4272).ResultsThe percentage of adults with usual daily folic acid intake above the tolerable upper intake level of 1000 μg was influenced more by the typical amount in supplements, while the median intake was influenced more by the ECGP fortification level. By manipulating the amount in at least two sources, it was possible to shift the distribution such that more women of childbearing age consumed the recommended intake of 400 μg of folic acid without increasing the percentage of adults with intake above the tolerable upper intake level. The results varied among population subgroups.ConclusionsOur results suggest that combined strategies are required to meet population recommendations for folic acid intake.


BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e027628 ◽  
Author(s):  
Christelene Jack Horton ◽  
Lalatendu Acharya ◽  
Ellen M Wells

ObjectivesThe aim of this study is to determine the association between length of time in the USA with blood lead (BPb).DesignPopulation-based cross-sectional study using data from the 2013–2016 National Health and Nutrition Examination Survey.SettingUSA.Participants5933 men and women (≥15 years); subgroups of men only (n=2867), women only (n=3064) and women of childbearing age (15–45 years) (n=1580).Primary and secondary outcomesThe primary outcome was BPb concentration. The main exposure variable was self-reported number of years spent in the USA, categorised as: born in the USA; 0–4 years; 5–9 years; 10–19 years and ≥20 years. We used linear regression models adjusted for race/ethnicity, education, blood cotinine, age, sex (as appropriate) and accounted for complex survey design.ResultsWomen of childbearing age who have lived 0–4 years in the USA have, on average, a 54% (95% CI 36% to 75%) higher BPb compared with women born in the USA. Corresponding results for all women, men and the entire population were 49% (95% CI 34% to 66%), 49% (95% CI 28% to 75%) and 49% (95% CI 33% to 66%), respectively. Similar, statistically significant, results were observed for other time periods (5–9 years, 10–19 years and ≥20 years); the magnitude of the association decreased with increasing time in the USA.ConclusionsThis study provides additional evidence that newcomers to the USA may be a population at higher risk of elevated BPb.


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