scholarly journals Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

2012 ◽  
Vol 181 (5) ◽  
pp. 1573-1584 ◽  
Author(s):  
Dolores Di Vizio ◽  
Matteo Morello ◽  
Andrew C. Dudley ◽  
Peter W. Schow ◽  
Rosalyn M. Adam ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Metastatic Disease ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Cancer Tissues

High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB

2005 ◽  
Vol 206 (2) ◽  
pp. 214-219 ◽  
Author(s):  
Tine Van de Sande ◽  
Tania Roskams ◽  
Evelyne Lerut ◽  
Steven Joniau ◽  
Hein Van Poppel ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acid ◽  
Nuclear Localization ◽  
Fatty Acid Synthase ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
High Level Expression ◽  
High Level ◽  
Cancer Tissues

scholarly journals Differential expression of proteins in human prostate cancer tissues probed by MALDI imaging mass spectrometry

2020 ◽  
Author(s):  
Amrita Mitra ◽  
Surya Kant Choubey ◽  
Rajdeep Das ◽  
Pritilata Rout ◽  
T. S Sridhar ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mass Spectrometry ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Expression Profiles ◽  
Imaging Mass Spectrometry ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Tissue Sections ◽  
Cancer Tissues

AbstractHistopathology, the gold-standard method for diagnosis of human prostate cancer, is based on the analysis of changes in cellular morphology and tissue architecture in chemically stained tissue sections. Even at the very early stages of cancer with minimal phenotypic changes in cellular morphologies, there might be detectable changes in the expression profiles of proteins. Over the last decade, imaging mass spectrometry has been used to explore the spatial distribution and expression profiles of several molecules with their twodimensional heterogeneity retained across the tissue section. In the present study, using MALDI mass spectrometry based tissue imaging, we report the differential expression of three proteins, vinculin, ribonuclease T2 and 60 kDa heat shock protein across human prostate tissue sections in regions pathologically demarcated as frankly malignant. In an independent analysis, quantitative proteomics revealed that in cancerous prostate tissues, ribonuclease T2 and 60 kDa heat shock protein were significantly overexpressed by 22.26- and 6 folds respectively compared to benign condition. Our results show the utility of this approach to probe differential protein expression in architecturally intact cancer tissues. In addition, we propose that ribonuclease T2 and 60 kDa heat shock protein might be developed as diagnostic biomarkers for prostate cancer in future.

scholarly journals Discrepancies between detection of bcl-2 byin situ hybridization and immunocytochemistry in human prostate cancer tissues

1998 ◽  
Vol 79 (6) ◽  
pp. 614-618 ◽  
Author(s):  
Michelangelo Fiorentino ◽  
Antonia D'Errico ◽  
Chiara Barozzi ◽  
Walter F. Grigioni
Keyword(s):  
Prostate Cancer ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Cancer Tissues

scholarly journals Analysis of XMRV integration sites from human prostate cancer tissues suggests PCR contamination rather than genuine human infection

Retrovirology ◽  
2011 ◽  
Vol 8 (1) ◽  
pp. 13 ◽  
Author(s):  
Jeremy A Garson ◽  
Paul Kellam ◽  
Greg J Towers
Keyword(s):  
Prostate Cancer ◽  
Human Infection ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Integration Sites ◽  
Cancer Tissues

Histone H1 expression in human prostate cancer tissues and cell lines

2011 ◽  
Vol 62 (2) ◽  
pp. 84-92 ◽  
Author(s):  
Shinya Sato ◽  
Satoru Takahashi ◽  
Makoto Asamoto ◽  
Makoto Nakanishi ◽  
Toshiaki Wakita ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Lines ◽  
Histone H1 ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Cancer Tissues

Technical aspects of Zn microanalysis of human prostate cancer tissues and cells

2009 ◽  
Vol 78 (10) ◽  
pp. S53-S57 ◽  
Author(s):  
M. Podgórczyk ◽  
W.M. Kwiatek ◽  
D. Grolimund ◽  
C. Borca
Keyword(s):  
Prostate Cancer ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Technical Aspects ◽  
Cancer Tissues
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