Culture-positive urinary tract infection following micturating cystourethrogram in children

Background Urinary Tract Infection implies presence of actively multiplying organisms in the urinary tract. Although it is infrequently associated with mortality, it is still a significant cause of morbidity. Early diagnosis is critical to preserve renal function of growing kidney.Objective Our purpose was to determine the clinical, microbiologic profile and antibiotic sensitivity of such infections in pediatric Urinary Tract Infection (UTI) patients at Dhulikhel Hospital.Methods A hospital based prospective descriptive study of 135 children from 2 months to 16 years, with clinical diagnosis of urinary tract infection who visited the pediatric department of Dhulikhel Hospital over the period of 15 months were enrolled in the study. All patients underwent routine urine analysis and culture. Children with recurrent UTI underwent micturating cystourethrogram (MCUG). Children with recurrent UTI of more than two years and with feature of pyelonephritis underwent USG abdomen as well. Complications and response of the treatment was observed in all cases of UTI. All data were entered in Epidata and data analysis was done using spss 16 version.Results Among 135 children, 32.5% were male and 67.4% were female. Fever was the most common presenting symptom in 74.80% of patients followed by dysuria in 54.1%. Among these children 95.6% had significant pyuria and 45% had culture positive infection. Children who showed positive for bacteriuria, Escherichia coli (78.7%) was the most common organism and are more than 80% sensitive to Amikacin, Gentamicin, Ceftriaxone, Ofloxacin, Nalidixic acid, Imipenem and Vancomycin. Co-trimoxazole was the most common drug used for treatment with a mean drug respond time of (mean±S.D) of 2.21±.78 days. 2±±. Children who had recurrent UTI were more prone to develop culture positive UTI (p=0.0001).Conclusion Urinary Tract Infection in female was almost twice more common than in male. Co-trimoxazole was the most common drug used for treatment, sensitivity of this drug was less than 50% for all organisms.Kathmandu Univ Med J 2013; 11(4): 319-324

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Is Culture-positive Urinary Tract Infection in Febrile Children Accurately Identified by Urine Dipstick or Microanalysis?

Journal of Emergency Medicine ◽

10.1016/j.jemermed.2012.05.006 ◽

2012 ◽

Vol 43 (6) ◽

pp. 1155-1159 ◽

Cited By ~ 6

Author(s):

Jack Perkins ◽

Karen Perkins ◽

Gary M. Vilke ◽

Faisal Y. Almazroua

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Dipstick ◽

Culture Positive

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Clinical, Epidemiological and Bacteriological Profile of Culture Positive Urinary Tract Infections in Febrile Children – A Cross Sectional Study

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/102 ◽

2021 ◽

Vol 8 (10) ◽

pp. 522-526

Author(s):

Bhavani Shankar Rokkam ◽

Chowdary Babu Menni ◽

Ramu Pedada ◽

Deepak Kumar Alikana

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Urine Culture ◽

Signs And Symptoms ◽

Cross Sectional ◽

Bacteriological Profile ◽

Tract Infections ◽

Culture Positive

BACKGROUND Urinary tract infections (UTI) constitute a common cause of morbidity in infants and children. When associated with abnormalities of urinary tract, they may lead to long-term complications including renal scarring, loss of function and hypertension. Most urinary tract infections remain undiagnosed if investigations are not routinely performed to detect them. Prompt detection and treatment of urinary tract infections and any complicating factors are important. The objective of the study is to know the clinical, epidemiological and bacteriological profile (i.e. clinical signs and symptoms, age, sex, family history, associated urinary tract abnormalities, & causative organisms) of urinary tract infections in febrile children with culture positive urinary tract infection. METHODS This descriptive, cross sectional observational study was conducted at outpatient clinics of our “child health clinics” between May 2016 and April 2017 (one year). All children aged 0 to 12 years with culture positive urinary tract infections were included in this study to evaluate the clinical, epidemiological and bacteriological profile. RESULTS A total of 69 children with culture positive urinary tract infections were included in this study. Out of 69 children included in this study, 36 (52.2 %) were females and 33 (47.8 %) were males. Overall female preponderance was seen and the M: F ratio was 0.9:1. But during first year of life in our study group we had more boys (10, 14.49 %) affected with urinary tract infection than girls. 49.3 % of urinary tract infections in the present study belonged to lower socio-economic status. Most common organism causing urinary tract infection in our group was E. coli (56.5 %). Fever (100 %), anorexia or refusal of feeds (52.2 %), dysuria (46.4 %), vomiting (46.4 %) and abdominal pain (39.1 %) were the predominant clinical manifestations observed in our study. CONCLUSIONS Urinary tract infection is a common medical problem in children and it should be considered as a potential cause of fever in children. As febrile children with urinary tract infection usually present with non-specific signs and symptoms, urine culture should be considered as a part of diagnostic evaluation. KEYWORDS Urinary Tract Infections (UTI), Febrile Children, Bacteriological Profile, Urine Culture

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A study of prevalence of culture positive UTI in children: clinical profile, risk factor analysis, and microbiological profile

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20185518 ◽

2019 ◽

Vol 6 (2) ◽

pp. 394

Author(s):

K. Rajendran ◽

Kiruba Shankar

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

Indian Academy ◽

Clinical Profile ◽

Differential Count ◽

Ascending Infection ◽

Study Population ◽

Culture Positive

Background: Urinary infection is one of the common infections occurring in children. Different literature says different definition for UTI. Indian Academy of Pediatrics defines urinary tract infection as the growth of a significant number of organisms of single species in urine culture with the presence of symptoms of UTI. The objective is to study the clinical profile of children with urine culture positive UTI.Methods: The study was conducted in Kovai medical centre and hospital Coimbatore. The sample size is 150 children. The study population includes children with culture-positive UTI who are admitted between October 2015 to September 2016 over a period of 1 year. Child’s history was then recorded as answers to the pre-prepared questionnaire in a proforma. Clinical examination was done, and the findings were recorded. Blood sampling was done for all patients and sent to a laboratory to measure total count, differential count, ESR.Results: Previous urinary tract infection was present in 2.7% of children. All children had the same organism grown in urine culture as in previous episode suggesting unresolved or persistent bacteremia. This is comparable with the literature stating unresolved bacteremia as the most common type of recurrent.Conclusions: The study group in which the risk factors were analysed had a female preponderance (may be due to the short urethra, easy ascending infection). In present study population fever and increased frequency are two important symptoms followed by abdominal pain.

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A STUDY OF BACTERIOLOGICAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY PATTERNS AMONG CULTURE POSITIVE URINARY TRACT INFECTION IN FEBRILE CHILDREN

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2018/537 ◽

2018 ◽

Vol 7 (19) ◽

pp. 2385-2389

Author(s):

Annapurna D ◽

Ramu P ◽

Jeevan V

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Antibiotic Susceptibility ◽

Bacteriological Profile ◽

Antibiotic Susceptibility Patterns ◽

Culture Positive ◽

Susceptibility Patterns

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Association of Vesicoureteric Reflux (VUR) in Children with Symptomatic Urinary Tract Infection (UTI) - in a Tertiary Care Hospital, Dhaka, Bangladesh

Bangladesh Journal of Child Health ◽

10.3329/bjch.v37i2.17264 ◽

2013 ◽

Vol 37 (2) ◽

pp. 79-84

Author(s):

Afroza Begum ◽

Habibur Rahman ◽

MM Hossain ◽

Golam Muinuddin ◽

Ranjit Ranjan Roy ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Renal Scarring ◽

Tertiary Care ◽

Vesicoureteric Reflux ◽

Pediatric Nephrology ◽

Care Hospital ◽

Age Group ◽

Micturating Cystourethrogram

Background: Vesicoureteric reflux is the most common urinary tract anomaly affecting the children which predisposes to higher rates of urinary tract infection and renal scarring than those without VUR. Objective: To find out the associations of VUR in children presented with UTI. Methodology: This cross sectional study was conducted in 36 children aged 1 month to 16 years who were admitted due to UTI in the Pediatric Nephrology Department of Bangabandhu Sheikh Mujib Medical University (BSMMU) from July 2009 to June 2010. UTI were evaluated by urinalysis, culture and sensitivity test, ultrasonography of the urinary system with post-voidal residue and micturating cystourethrogram subsequently. Results: This study revealed that UTI were most frequent in boys (P<0.001). Maximum number 19(52.7%) of UTI cases were detected between 12 months -60 months age group of children. Highest number of bilateral hydronephrosis 7(71.43%) and VUR 12(63.15%) were also detected in the were detected in 2-23 months age group of children. Maximum number of 22/38 kidneys (57.90%) with refluxing units were detected between 12 months to 60 months (1-5 years) age group and out of this 16(72.72%) units are of severe grades. Conclusion: Children presented with UTI along with features of obstructive- uropathy must be investigated early and carefully for VUR to prevent recurrent UTI and renal damage. DOI: http://dx.doi.org/10.3329/bjch.v37i2.17264 BANGLADESH J CHILD HEALTH 2013; VOL 37 (2) : 79-84

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Isolated gross haematuria: A rare clinical presentation in neonate with urinary tract infection

Journal of Kathmandu Medical College ◽

10.3126/jkmc.v4i3.18240 ◽

2017 ◽

Vol 4 (3) ◽

pp. 104-106

Author(s):

Pawana Kayastha ◽

Rydam Basnet ◽

Ramesh Kant Adhikari

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Clinical Presentation ◽

Older Children ◽

Male Baby ◽

History Of ◽

Gross Haematuria ◽

Culture Positive

Gross haematuria is uncommon in the fi rst month of life and etiologies of haematuria in the newborn is different from those in older children. we reported a six days old term male baby who was brought by parents with isolated complain of red colored urine for one day and his mother had culture positive urinary tract infection prior to delivery. The baby was diagnosed to have culture positive urinary tract infection. Our fi ndings suggest the diversity of clinical presentation of urinary tract infection in neonates and also some relationship between the history of urinary tract infection in mother and occurrence of urinary tract infection in neonate.

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Recent Antibiotic Sensitivity Pattern of Escherichia Coli in Urinary Tract Infection

TAJ Journal of Teachers Association ◽

10.3329/taj.v30i1.39125 ◽

2018 ◽

Vol 30 (1) ◽

pp. 61-65

Author(s):

Md Abdul Bari ◽

Mashiur Arefin ◽

Moriom Nessa ◽

Golam Mostofa ◽

Tafiqul Islam

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

Antibiotic Sensitivity ◽

E Coli ◽

Sensitivity Pattern ◽

Marked Resistance ◽

Culture Positive

The objective of the study is to assess the recent sensitivity pattern of Escherichia coli in Urinary tract infection (UTI). Widespread use of antibiotics has led to the emergence of resistant microorganisms. As the antibiotic sensitivity patterns of the microorganisms are frequently changing, this retrospective analysis was designed to assess the recent antibiotic sensitivity pattern of Escherichia coli (E. coli) in urinary tract infection among the human population. Details of 358 urine culture positive reports for E. coli and their antibiotic sensitivity pattern pertaining to the study period of 6 months from Jan 2017 to June 2017 were collected from Microbiology Laboratory of Diagnostic Centers at Rajshahi and the results were statistically analyzed. The antibiotics tested for sensitivity were amikacin, gentamycin, ciprofloxacin, levofloxacin, cotrimoxazole, nitrofurantoin, ceftazidime, ceftriaxone and cefixime. The sensitivity pattern of E.coli to antibiotics in UTI was amikacin (82.68 gentamycin (75.97%), nitrofurantoin (70.67), levofloxacin (44.13%), ceftazidime (42.17%), co-trimoxazole (40.78%), ceftriaxone (38.54%), ciprofloxacin (35.75%), and cefixime (24.02%). The study highlighted the marked resistance of E. coli to quinolones and third generation cephalosporins.TAJ 2017; 30(1): 61-65

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Predictors of culture positive urinary tract infection in the emergency department

European Geriatric Medicine ◽

10.1016/j.eurger.2012.07.146 ◽

2012 ◽

Vol 3 ◽

pp. S76

Author(s):

C. Sánchez-Castellano ◽

N. Pérez-Abascal ◽

R. Torremocha-García ◽

B. Montero-Errasquín ◽

J. Mateos-Nozal ◽

...

Keyword(s):

Emergency Department ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Culture Positive

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Study on microbiology of urinary tract infection and the status of urinary isolates in pregnant women

Medical Journal of Shree Birendra Hospital ◽

10.3126/mjsbh.v12i2.8793 ◽

2015 ◽

Vol 12 (2) ◽

Author(s):

Sharmila Parajuli

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Asymptomatic Bacteriuria ◽

Culture Method ◽

First Trimester ◽

Number Of Patients ◽

Sensitivity Pattern ◽

Culture Positive

Background: Urinary tract infection (UTI) is one of the most frequently encountered problems owing to significant number of patients needing hospitalization during pregnancy. The incidence of UTI in pregnant women is reported to be high up to 7-8%. Materials and methods: This is a prospective study conducted in Valley Maternity Hospital during a period of 6 months (Jan 2011 to June 2011). 520 MSU (Mid stream urine samples) from pregnant women clinically suspected of urine infection were evaluated by urine dipstick analysis, microscopic and culture method. The isolates were identified and antibiotic sensitivity pattern was determined by standard protocol. Results: The majority of the patients were in-between the age group of 20-30years- 338cases (65%) and these patients usually presented in the first trimester of pregnancy- 317cases (60.96%).  Out of the 520 clinically suspected UTI cases, 232 (44.61%) was culture positive. Out of the culture positive cases; Escherichia coli (E.coli) was the most common accounting for a total of 144cases (80%). Nitrofurantoin was found to be the most effective drug against the gram negative (Gm-ve) bacteria. Similarly, Ampicillin, Amoxycillin and Cloxacillin were found to be effective agent against gram positive (Gm+ve) bacteria. Conclusion: Screening for bacteriuria is recommended among all pregnant women at the first prenatal visit and in the subsequent trimesters of pregnancy. Prompt treatment of symptomatic UTI and asymptomatic bacteriuria is required in pregnant women to avoid complications like preterm birth, low birth weight and increased perinatal mortality. Key words: UTI, Pregnant women, Antibiotics, Culture method.

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