Relation of Highly Sensitive Cardiac Troponin T in Hypertrophic Cardiomyopathy to Left Ventricular Mass and Cardiovascular Risk

2014 ◽  
Vol 113 (7) ◽  
pp. 1240-1245 ◽  
Author(s):  
Gilbert Cramer ◽  
Jeannette Bakker ◽  
Frank Gommans ◽  
Marc Brouwer ◽  
Maurice Kurvers ◽  
...  
Author(s):  
Zhaowei Kong ◽  
Haifeng Zhang ◽  
Jinlei Nie ◽  
Li Wen ◽  
Qingde Shi ◽  
...  

AbstractThe purpose of this study was to determine whether exercise training mediated cardiac troponin T (cTnT) and whether this was associated with increases in left ventricular mass (LVM). Fifty-four sedentary obese women were randomised to high-intensity interval training (HIIT, repeated 4–min cycling at 90% V̇O2max interspersed with 3–min rest), work-equivalent continuous aerobic training (CAT, continuous cycling at 60% V̇O2max) or a control group (CON). Resting serum cTnT was assessed using a high-sensitivity assay before and after 12 weeks of training. LVM was determined from 2D echocardiography at the same timepoints. Both HIIT and CAT induced a similar elevation (median 3.07 to 3.76 ng.l−1, p<0.05) in resting cTnT compared with pre-training and the CON (3.49 to 3.45 ng.l−1, p>0.05). LVM index in HIIT increased (62.2±7.8 to 73.1±14.1 g.m−2, p<0.05), but not in CAT (66.1±9.7 to 67.6±9.6 g.m−2, p>0.05) and CON (67.9±9.5 to 70.2±9.1 g.m−2, p>0.05). Training-induced changes in resting cTnT did not correlate with changes in LVM index (r=−0.025, p=0.857). These findings suggest that twelve weeks of either HIIT or CAT increased resting cTnT, but the effects were independent of any changes in LVM in sedentary obese women.


2009 ◽  
Vol 15 (7) ◽  
pp. S161
Author(s):  
Shigeru Matsui ◽  
Junnichi Ishii ◽  
Tousei Hashimoto ◽  
Masanori Okumura ◽  
Tadashi Nakano ◽  
...  

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