AbstractThe purpose of this study was to determine whether exercise training mediated
cardiac troponin T (cTnT) and whether this was associated with increases in left
ventricular mass (LVM). Fifty-four sedentary obese women were randomised to
high-intensity interval training (HIIT, repeated 4–min cycling at
90% V̇O2max interspersed with 3–min rest),
work-equivalent continuous aerobic training (CAT, continuous cycling at
60% V̇O2max) or a control group (CON). Resting serum
cTnT was assessed using a high-sensitivity assay before and after 12 weeks of
training. LVM was determined from 2D echocardiography at the same timepoints.
Both HIIT and CAT induced a similar elevation (median 3.07 to
3.76 ng.l−1, p<0.05) in resting
cTnT compared with pre-training and the CON (3.49 to
3.45 ng.l−1, p>0.05). LVM index in
HIIT increased (62.2±7.8 to
73.1±14.1 g.m−2, p<0.05),
but not in CAT (66.1±9.7 to
67.6±9.6 g.m−2, p>0.05)
and CON (67.9±9.5 to 70.2±9.1 g.m−2,
p>0.05). Training-induced changes in resting cTnT did not
correlate with changes in LVM index (r=−0.025,
p=0.857). These findings suggest that twelve weeks of either HIIT
or CAT increased resting cTnT, but the effects were independent of any changes
in LVM in sedentary obese women.