Effect of sialyllactose administration on growth performance and intestinal epithelium development in suckling piglets

A total of 45 sows (Landrace × Yorkshire) and their litters were used in this study to evaluate the efficacy of nucleotide supplementation on reproductive performance, growth performance, fecal microflora, and blood profiles in sows and piglets. Sows were allocated to one of three treatments (15 pigs per treatment and the average parity was 4.13). Dietary treatments consisted of (1) CON: basal diet, (2) T1: CON + 0.5% nucleotides, and (3) T2: CON + 1.0% nucleotides. In this study, the average daily feed intake during lactation and back fat at weaning day was increased linearly (P < 0.05) in sows with the increase in nucleotide supplementation levels. Sows receiving increasing levels of nucleotides had linearly increased fecal Lactobacillus counts and decreased Escherichia coli counts at weaning day (P < 0.05). Linear reduction of the epinephrine, norepinephrine, and cortisol in sows was observed at weaning day, whereas superoxide dismutase was increased linearly (P < 0.05). Body weight and average daily gain in piglets were linearly (P < 0.05) increased with the increasing levels of nucleotides. Linear increase (P < 0.05) was also observed on total piglets born, live piglets, and piglet survival. The current study demonstrated the importance of nucleotides in the diets of sows to improve sow and piglet performance.

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Fructooligosaccharides improve growth performance and intestinal epithelium function in weaned pigs exposed to enterotoxigenic Escherichia coli

Food & Function ◽

10.1039/d0fo01998d ◽

2020 ◽

Vol 11 (11) ◽

pp. 9599-9612

Author(s):

Lei Liu ◽

Daiwen Chen ◽

Bing Yu ◽

Heng Yin ◽

Zhiqing Huang ◽

...

Keyword(s):

Escherichia Coli ◽

Growth Performance ◽

Intestinal Epithelium ◽

Intestinal Injury ◽

Enterotoxigenic Escherichia Coli ◽

Weaned Pigs ◽

Protective Potential

This study was conducted to explore the protective potential of fructooligosaccharides (FOS) against enterotoxigenic Escherichia coli (ETEC)-induced inflammation and intestinal injury in weaned pigs.

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Effects of dietary methionine supplementation on growth performance, intestinal morphology, antioxidant capacity and immune function in intra‐uterine growth‐retarded suckling piglets

Journal of Animal Physiology and Animal Nutrition ◽

10.1111/jpn.13084 ◽

2019 ◽

Vol 103 (3) ◽

pp. 868-881 ◽

Cited By ~ 4

Author(s):

Hao Zhang ◽

Yue Li ◽

Yueping Chen ◽

Zhixiong Ying ◽

Weipeng Su ◽

...

Keyword(s):

Antioxidant Capacity ◽

Immune Function ◽

Growth Performance ◽

Intestinal Morphology ◽

Uterine Growth ◽

Suckling Piglets ◽

Methionine Supplementation

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The influence of infection in the urinary tract of sows on arthritis, facial lesions and weight gain in suckling piglets

Research Society and Development ◽

10.33448/rsd-v9i10.9166 ◽

2020 ◽

Vol 9 (10) ◽

pp. e9779109166

Author(s):

Lívia Mendonça Pascoal ◽

Sarah Rodrigues Chagas ◽

Mariana Dall'Agnol ◽

Maria Clorinda Soares Fioravanti ◽

Moema Pacheco Chediak Matos ◽

...

Keyword(s):

Urinary Tract Infection ◽

Risk Factor ◽

Urinary Tract ◽

Growth Performance ◽

Close Correlation ◽

Common Disease ◽

Disease Development ◽

Negative Effect ◽

Suckling Piglets ◽

In Pregnancy

Urinary tract infection (UTI) is a common disease in sows, it influences their yield and can also affect piglets. There is a small number of studies in the literature reporting close correlation between UTI in sows and disease development or reduced performance in piglets. Therefore, the aim of the present study is to test whether UTI in pregnancy influences disease development and the growth performance of suckling piglets. Healthy sows, presenting parity 1 to 4, were divided into two groups: UTI (+) (36 sows with UTI) and UTI (-) (36 sows without UTI). After delivery, piglets were monitored for diarrhea, omphalitis, arthritis and facial lesions. Average weaning weight (AWW) was calculated to measure growth performance. There was no difference in diarrhea and omphalitis between groups. However, parity 3 sows and all-parity analyses showed higher frequency of piglets with arthritis and facial lesions. The UTI (+) group showed lower AWW than the UTI (-) group in parity 4 sows and in all-parity analyses applied to growth performance. In conclusion, UTI in sows during pregnancy is a risk factor for arthritis and facial lesions in suckling piglets, as well as has negative effect on their growth performance.

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Fructooligosaccharides improves growth performance and intestinal epithelium function in weaned pigs exposure to Enterotoxigenic Escherichia coli

10.21203/rs.3.rs-45384/v1 ◽

2020 ◽

Author(s):

Lei Liu ◽

daiwen Chen ◽

Bing Yu ◽

Yin Heng ◽

Zhiqing Huang ◽

...

Keyword(s):

Escherichia Coli ◽

Amino Acid ◽

Growth Performance ◽

Intestinal Epithelium ◽

Amino Acid Transporter ◽

Enterotoxigenic Escherichia Coli ◽

Villus Height ◽

Weaned Pigs ◽

Glucose Transporter 2 ◽

Acid Transporter

Abstract Background This study was conducted to explore the protective potential of Fructooligosaccharides (FOS) against Enterotoxigenic Escherichia coli (ETEC)-induced inflammation and intestinal injury in weaned pigs. Methods Twenty-four weaned pigs were randomly assigned into three groups: (1) non-challenge (CON), (2) ETEC-challenge (ECON), and (3) ETEC challenge + 250 mg/kg FOS (EFOS). On day 19, non-challenged pigs were orally infused with sterilized culture while pigs in other groups were orally infused with ETEC (2.5 × 1010 colony-forming units). After 3 days, pigs were slaughtered for sample collection. Results We show that ETEC-challenged significantly reduced average daily gain (ADG); however, FOS improved the ADG (P < 0.05) and apparent digestibility of crude protein (CP), gross energy (GE), and ash in the ETEC-challenged pigs (P < 0.05). FOS reduced plasma concentrations of IL-1β and TNF-α, and elevated the concentrations of immunoglobulin A (IgA) and immunoglobulin M (IgM) (P < 0.05). Interestingly, FOS elevated villus height in duodenum, and elevated the ratio of villus height to crypt depth in the duodenum and ileum in the ETEC-challenged pigs (P < 0.05). Moreover, FOS increased lactase activity in the duodenum and ileum (P < 0.05). The activities of sucrase and alkaline phosphatase (AKP) were higher in EFOS group than in the ECON group (P < 0.05). Importantly, FOS up-regulated the expressions of critical genes in intestinal epithelium function such as zonula occludens-1 (ZO-1), L-type amino acid transporter-1 (LAT1), and cationic amino acid transporter-1 (CAT1) in the duodenum and the expressions of ZO-1 and glucose transporter-2 (GLUT2) in the jejunum (P < 0.05). FOS also up-regulated the expressions of occludin, fatty acid transporter-4 (FATP4), sodium glucose transport protein 1 (SGLT1), and GLUT2 in the ileum (P < 0.05). FOS significantly increased the concentrations of acetic acid, propionic acid and butyric acid in the cecal digesta. Additionally, FOS reduced the populations of Escherichia coli, but elevated the populations of Bacillus and Bifidobacterium in the caecal digesta (P < 0.05). Conclusions These results suggested that FOS can improve the growth performance and intestinal health in weaned pigs upon ETEC challenge, which was associated with suppressed inflammatory responses and improved intestinal epithelium functions and microbiota.

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Creep feeding improves growth performance of suckling piglets

Revista Brasileira de Zootecnia ◽

10.1590/rbz4720170081 ◽

2018 ◽

Vol 47 (0) ◽

Cited By ~ 2

Author(s):

Sang In Lee ◽

In Ho Kim

Keyword(s):

Growth Performance ◽

Creep Feeding ◽

Suckling Piglets

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The effect of creep feed and diet complexity on growth performance in suckling and weaned pigs

Revista Colombiana de Ciencias Pecuarias ◽

10.17533/udea.rccp.v33n3a04 ◽

2020 ◽

Vol 33 (3) ◽

pp. 159-171

Author(s):

Paige K Isensee ◽

Sarah E ◽

Lindsey G Wichman ◽

Autumn L Thoma ◽

Young D Jang

Keyword(s):

Body Weight ◽

Growth Performance ◽

Average Daily Gain ◽

Feed Ratio ◽

Initial Body Weight ◽

Weaned Pigs ◽

Creep Feed ◽

Suckling Piglets ◽

D 12 ◽

Dietary Treatments

Background: Creep feed is offered to suckling piglets to introduce solid feed and provide extra nutrients in late lactation. However, the effect of creep feed is inconsistent; there is little information about the effect of creep diet complexity on piglet performance. Objective: Two experiments were conducted to evaluate the effect of creep feed and its complexity on growth performance of suckling and weaned pigs. Methods: In Exp. 1, eight litters (average 19.9 ± 1.1 d of age; initial piglet weight: 6.74 ± 1.2 kg) were allotted to two dietary treatments considering breed, litter size and weight, as follows: no creep feed (n=3) and creep feed (n=5; offered for 8 days before weaning). At weaning (d 28 of age), the pigs were divided into three treatments (6 pigs/pen, 3 replicates; initial body weight: 9.66 ± 0.34 kg) balanced by gender, body weight, and breed, as follows: creep feed eaters, creep feed non-eaters, and no creep feed. In Exp. 2, two different types of creep feed were offered to suckling piglets (initial piglet weight: 3.79 ± 0.55 kg) in seven litters from d 12 of age (average 12.0 ± 1.3 d of age) to weaning (d 25 of age). Treatments were: HCF (n=4): highly-complex creep diet containing 3% fish meal, 2.4% blood meal, and 15% whey; and 2) LCF (n=3): lowly-complex creep diet without the mentioned ingredients. At weaning, only eater pigs were divided into 2 treatments (6 pigs/pen, 3 replicates; initial body weight: 7.53 ± 0.97 kg) balanced by gender, breed and body weight as follows: HCF eaters and LCF eaters. In both experiments, creep feed was mixed with 1% Cr2O3 to measure fecal color for eater/non-eater categorization and the pigs were fed a common nursery diet for 21 days. Results: In both experiments, there were no differences on piglet weaning weight and overall nursery growth performance among the treatments. In Exp. 2, the creep feed intake and percentage of eaters per litter were not different between the HCF and LCF treatments, whereas the HCF eaters tended to have a greater average daily gain (p=0.08) and gain to feed ratio (p=0.09) than the LCF eaters during d 7-14 postweaning. Conclusion: Creep feed did not affect overall piglet growth in suckling and nursery phases, but its complexity might affect pig growth in the early nursery phase.

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Improved Milk Glutamine Level and Growth Performance of Suckling Piglets by Glutamine Supplementation in Maternal Diet

Annals of Animal Science ◽

10.1515/aoas-2017-0040 ◽

2018 ◽

Vol 18 (2) ◽

pp. 441-452 ◽

Cited By ~ 2

Author(s):

X.F. Yang ◽

J.F. Qin ◽

L. Wang ◽

K.G. Gao ◽

C.T. Zheng ◽

...

Keyword(s):

Growth Performance ◽

Milk Yield ◽

Feed Intake ◽

Maternal Diet ◽

Average Daily Gain ◽

Glutamine Supplementation ◽

Large White ◽

Isoleucine Leucine ◽

Lactating Sows ◽

Suckling Piglets

Abstract Glutamine plays an important role in neonatal growth and health. It is unknown whether supplementing the lactating sows’ diet with glutamine will benefit the growth performance and intestinal development of suckling piglets through increasing content of milk glutamine. A total of 24 lactating sows (Large White) were fed diets supplemented with/without 1% glutamine throughout the 21-d lactation. Feed intake of the sows was recorded, blood and milk samples were collected. Piglets were weighed at birth and weaning, one piglet randomly selected from each litter was sacrificed for morphological analysis of the small intestine. Average daily feed intake of the sows did not differ between control and glutamine groups. Concentrations of total protein and urea nitrogen in sows’ serum was increased by glutamine at d 14 of lactation (P<0.05). Contents of glutamine in both plasma and milk of sows were significantly increased by glutamine supplementation throughout lactation (P<0.01). Concentrations of proline, citrulline, valine, isoleucine, leucine, and arginine in sows’ plasma were increased by glutamine supplementation (all P<0.05). Milk yield was increased by glutamine supplementation at d 14 and 21 of lactation (P<0.05). Supplementing the lactating sows’ diet with glutamine increased average daily gain (P=0.006), weaning weight (P=0.032), as well as villous height and ratio of villous height:crypt depth in duodenum of the suckling piglets (both P<0.05). Collectively, supplementing lactating sows’ diet with 1% glutamine significantly improved the growth performance of suckling piglets through elevating milk yield and glutamine content in the milk.

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