scholarly journals The association of whole grain consumption with incident type 2 diabetes: the Women's Health Initiative Observational Study

2013 ◽  
Vol 23 (6) ◽  
pp. 321-327 ◽  
Author(s):  
Emily D. Parker ◽  
Simin Liu ◽  
Linda Van Horn ◽  
Leslie F. Tinker ◽  
James M. Shikany ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Observational Study ◽  
Women's Health ◽  
Whole Grain ◽  
Incident Type ◽  
Women's Health Initiative ◽  
Health Initiative ◽  
Incident Type 2 Diabetes ◽  
The Women’S Health Initiative

scholarly journals Association between Dietary Energy Density and Incident Type 2 Diabetes in the Women’s Health Initiative

2017 ◽  
Vol 117 (5) ◽  
pp. 778-785.e1 ◽  
Author(s):  
Melanie D. Hingle ◽  
Betsy C. Wertheim ◽  
Marian L. Neuhouser ◽  
Lesley F. Tinker ◽  
Barbara V. Howard ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Energy Density ◽  
Women's Health ◽  
Dietary Energy ◽  
Incident Type ◽  
Health Initiative ◽  
Incident Type 2 Diabetes ◽  
Dietary Energy Density ◽  
The Women’S Health Initiative

scholarly journals Greater Adherence to the Portfolio Diet Is Associated with Lower Incidence of Type 2 Diabetes in the Women's Health Initiative

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1034-1034
Author(s):  
Andrea Glenn ◽  
Kenneth Lo ◽  
David Jenkins ◽  
Beatrice Boucher ◽  
Anthony Hanley ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Women's Health ◽  
Postmenopausal Women ◽  
Lower Risk ◽  
Incident Type ◽  
Health Initiative ◽  
Incident Type 2 Diabetes ◽  
Diet Score ◽  
The Women’S Health Initiative

Abstract Objectives To assess the association of the plant-based cholesterol-lowering diet, the Portfolio Diet, with incident type 2 diabetes in women. Methods We followed 147,732 postmenopausal women initially free of diabetes in the Women's Health Initiative (WHI) Clinical Trials and Observational Study from 1993 through 2017. Adherence to the Portfolio Diet was assessed using an a priori diet index based on six food categories (high in plant protein [soy & pulses], nuts, viscous fiber, plant sterols and monounsaturated fat, and low in saturated fat) that were previously found to lower cardiovascular risk factors in the Portfolio Diet trials. We used Cox proportional-hazard models to estimate hazard ratios (HRs) and 95% confidence intervals (CI) of the association of adherence to a Portfolio Diet score with incident type 2 diabetes, adjusting for potential confounders (demographics, lifestyle behaviors, and medical history). The Portfolio Diet score was cumulatively assessed at baseline and year three using a validated food frequency questionnaire. Type 2 diabetes diagnosis was ascertained by self-reported medication use. Results There were 14,096 cases of incident type 2 diabetes over a mean follow-up of 14.3 years. In the fully adjusted models, adherence to the Portfolio Diet score was associated with a lower risk of incident type 2 diabetes (HR, 0.88, CIs, 0.83, 0.93; P for trend < 0.001), comparing the highest to lowest quartiles of adherence. Results remained similar across subgroup analyses (age, body mass index, family history of diabetes, and ethnicity) and several sensitivity analyses. Conclusions Among postmenopausal women, higher adherence to the Portfolio Diet was associated with lower incident type 2 diabetes. These findings are the first to show that the Portfolio Diet may be associated with a lower risk of type 2 diabetes and warrants further investigation. Funding Sources The WHI was funded by the National Heart, Lung, and Blood Institute, National Institutes of Health, and the U.S. Department of Health and Human Services. AJG was supported by the Banting & Best Diabetes Centre Tamarack Graduate Award in Diabetes Research, the Peterborough K.M. Hunter Charitable Foundation Graduate Award, and an Ontario Graduate Scholarship. JLS was funded by a Diabetes Canada Clinician Scientist Award.

scholarly journals Multiple Healthful Dietary Patterns and Type 2 Diabetes in the Women's Health Initiative

2016 ◽  
Vol 183 (7) ◽  
pp. 622-633 ◽  
Author(s):  
Elizabeth M. Cespedes ◽  
Frank B. Hu ◽  
Lesley Tinker ◽  
Bernard Rosner ◽  
Susan Redline ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Women’S Health ◽  
Women's Health ◽  
Dietary Patterns ◽  
Women's Health Initiative ◽  
Women’S Health Initiative ◽  
Health Initiative ◽  
The Women’S Health Initiative

scholarly journals Alignment of dietary patterns with the Dietary Guidelines for Americans 2015-2020 and risk of all-cause and cause-specific mortality in the Women’s Health Initiative Observational Study

2020 ◽  
Author(s):  
Stephanie M George ◽  
Jill Reedy ◽  
Elizabeth M Cespedes Feliciano ◽  
Aaron Aragaki ◽  
Bette J Caan ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Observational Study ◽  
Women's Health ◽  
Diet Quality ◽  
Lower Risk ◽  
Dietary Guidelines ◽  
Women's Health Initiative ◽  
Health Initiative ◽  
The Women’S Health Initiative

Abstract Poor diet quality is a leading risk factor for death in the United States (U.S.). We examined the association between Healthy Eating Index-2015 (HEI-2015) scores and death from all-causes, cardiovascular disease (CVD), cancer, Alzheimer’s Disease and Dementia not otherwise specified (NOS) among postmenopausal women in the Women’s Health Initiative Observational Study (1993-2017). This analysis included 59,388 participants who completed a food frequency questionnaire and were free of cancer, CVD and diabetes at enrollment. Stratified Cox proportional hazards models were fit using person-years from enrollment as the underlying time metric. We estimated multivariable adjusted hazard ratios and 95% confidence intervals for risk of death associated with HEI-2015 quintiles, with higher scores reflecting more optimal diet quality. Over a median of 18.2 years, 9,679 total deaths 3,303 cancer deaths, 2,362 CVD deaths, and 488 deaths from Alzheimer’s Disease and Dementia NOS occurred. Compared to those with lower scores, women with higher HEI-2015 scores had an 18% lower risk of all-cause mortality and 21% lower risk of cancer mortality. HEI-2015 scores were not associated with mortality from CVD, Alzheimer’s Disease and dementia NOS. Consuming a diet aligned with 2015-2020 U.S. Dietary Guidelines may have beneficial impacts for preventing death from cancer and overall.

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