P-23 SEROLOGICAL PROFILE OF HEPATITIS B AND C IN REUMATHOLOGIC PATIENTS IN USE OF IMMUNOSSUPRESSIVE THERAPY

Introduction: The primary aim of the study was to determine the knowledge of dental practitioners regarding HBV serological markers. Second objective was to determine prevalence of occupational exposures to HBV amongst dentists. Methodology: A questionnaire was constructed pertaining to various aspects of HBV serology; validated by an expert panel; and piloted at 49 dentists. A Cronbach-alpha value of 0.7 was attained and thus extensive survey was conducted among dentists in routine practise treating hepatitis B patients at dental teaching hospitals in Peshawar, KP. The data was analysed using SPSS v.22. Results: A response rate of 58% (a total of 290 respondents) was attained. All respondents were vaccinated against HBV. Over 50% reported not to follow Standard precautions for every patient. Overall, 20.3% experienced HBV exposure, eight were administered PEP. Fifty-four percent of FYs; 74.5% PGTs and 71.6% of faculty dentists correctly answered: HBsAg to be the ‘serological hallmark of HBV infection’; this was the most correctly answered question. Sixty-four percent dentists failed to identify the infectious carrier phase. Over 50% of dentists in each category failed to correctly answer 5/8 of the HBV serology. Conclusions: Over 20% reported HBV occupational exposure but zero transmissions. Majority of dentists did not have correct information on HBV serological profile which may jeopardise cross-infection control. Further education on HBV serological markers and its clinical relevance to dentistry along with stringent adherence to Standard precautions is recommended.

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Serological profile of “healthy” hepatitis B surface antigen carriers and heterosexual transmission of hepatitis B virus

Infection ◽

10.1007/bf01643764 ◽

1991 ◽

Vol 19 (1) ◽

pp. 56-56

Author(s):

N. C. Tassopoulos ◽

Melpomeni Paraloglou-Ioannides

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Heterosexual Transmission ◽

Serological Profile ◽

B Virus

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Serological profile of hepatitis B in children after the introduction of its vaccination in Burkina Faso

Pediatric Reports ◽

10.4081/pr.2019.8248 ◽

2019 ◽

Vol 11 (4) ◽

Author(s):

Makoura Barro ◽

Diane Valea ◽

Saga Alain Ouermi ◽

Sanata Sessouma ◽

Bintou Sanogo ◽

...

Keyword(s):

Hepatitis B ◽

Burkina Faso ◽

Large Scale ◽

Hepatitis B Vaccine ◽

Public Health Issue ◽

Prospective Data ◽

Serological Profile ◽

Significant Difference ◽

Bobo Dioulasso ◽

Expanded Program On Immunization

Viral hepatitis B is a public health issue. We establish the children serological profile of hepatitis B in Bobo-Dioulasso, six years after the introduction of hepatitis B vaccine into the Expanded Program on Immunization. This was a descriptive study of prospective data collection carried out in the Department of Pediatrics and the laboratory of virology of the Centre MURAZ of Bobo-Dioulasso between March 2013 and May 2013. Blood samples were made in search of the following hepatitis B serological markers: anti-HBcAb total, HBsAg, Ac anti-HBs, HBeAg, AcHBs, IgM anti-HBc total. The ELISA method with the Monolisa BIORAD reagents was used. A total of 2015 children were included, 1026 (50, 9%) boys and 989 (49.1%) girls, at an average age of 58±48 months. Out of these 2015 children, 53 (2.6%) were positive to HBsAg including 19 vaccinated cases, one child has received 3 doses plus 1 booster dose of hepatitis B vaccine. We found no statistically significant difference in the carriage of serologic markers of hepatitis B between the unvaccinated group and the vaccinated group. Large-scale studies should be carried out in Burkina Faso to see the real impact of vaccination on the health of our populations.

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