Poster 36: Cognitive Functioning in Older Adults Over Time: Effect of Traumatic Brain Injury and APOE ε4 Allele Status

2007 ◽  
Vol 88 (10) ◽  
pp. e15
Author(s):  
Amanda Sacks ◽  
Teresa Ashman ◽  
Joshua Cantor ◽  
Mathew Egan
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Functioning ◽  
Time Effect ◽  
Apoe Ε4 ◽  
Allele Status ◽  
Ε4 Allele ◽  
Over Time

scholarly journals APOE-ε4 Genotype is Associated with Elevated Post-Concussion Symptoms in Military Veterans with a Remote History of Mild Traumatic Brain Injury

2018 ◽  
Vol 34 (5) ◽  
pp. 706-712 ◽  
Author(s):  
Victoria C Merritt ◽  
Kristina M Lapira ◽  
Alexandra L Clark ◽  
Scott F Sorg ◽  
Madeleine L Werhane ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Military Veterans ◽  
Primary Outcome Measure ◽  
Apoe Ε4 ◽  
Stress Symptoms ◽  
History Of ◽  
Ε4 Allele

Abstract Objective We evaluated the influence of the APOE-ε4 allele on post-concussive symptoms in military Veterans with a remote history of mild traumatic brain injury (mTBI). Method Participants (N = 77) were administered neuropsychiatric measures, on average, approximately 5 years following their most recent mTBI and provided a DNA sample for APOE genotyping. Veterans were divided into two groups based on their ε4 status (n = 14 ε4+, n = 63 ε4–). The Neurobehavioral Symptom Inventory (NSI) was the primary outcome measure, from which a total score was derived, as well as three symptom clusters (somatic, cognitive, and affective). Results ANCOVAs showed a significant main effect of ε4 genotype on the NSI total score and somatic symptom cluster after adjusting for posttraumatic stress symptoms and mTBI history (p = .019–.028, ηp2 = .064–.073), such that ε4+ Veterans endorsed significantly greater symptoms than ε4– Veterans. Conclusions Our findings suggest that genetic risk may help to explain the poorer long-term outcomes often observed in this population.

Poster 23: Cognitive Functioning and Community Integration in Older Adults With Traumatic Brain Injury

2008 ◽  
Vol 89 (10) ◽  
pp. e34
Author(s):  
Stacey Belkonen ◽  
Wayne Gordon ◽  
Ren Krinick ◽  
Joshua Cantor ◽  
Teresa Ashman ◽  
...  
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Functioning ◽  
Community Integration

scholarly journals Measuring Change Over Time: A Systematic Review of Evaluative Measures of Cognitive Functioning in Traumatic Brain Injury

2019 ◽  
Vol 10 ◽  
Author(s):  
Andrea D'Souza ◽  
Shirin Mollayeva ◽  
Nicole Pacheco ◽  
Fiza Javed ◽  
Angela Colantonio ◽  
...  
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Functioning ◽  
Change Over Time ◽  
Measuring Change ◽  
Over Time

A Comparison of Cognitive Functioning in Older Adults With and Without Traumatic Brain Injury

2008 ◽  
Vol 23 (3) ◽  
pp. 139-148 ◽  
Author(s):  
Teresa A. Ashman ◽  
Joshua B. Cantor ◽  
Wayne A. Gordon ◽  
Amanda Sacks ◽  
Lisa Spielman ◽  
...  
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Functioning

Cognitive control constrains memory attributions

2019 ◽  
Vol 42 ◽  
Author(s):  
Colleen M. Kelley ◽  
Larry L. Jacoby
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Control

Abstract Cognitive control constrains retrieval processing and so restricts what comes to mind as input to the attribution system. We review evidence that older adults, patients with Alzheimer's disease, and people with traumatic brain injury exert less cognitive control during retrieval, and so are susceptible to memory misattributions in the form of dramatic levels of false remembering.

Older adults’ experiences of community integration following traumatic brain injury”

2014 ◽  
Vol 42 (3) ◽  
Author(s):  
James Kent ◽  
◽  
Valerie Wright St Clair ◽  
Paula Kersten ◽  
◽  
...  
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Community Integration

scholarly journals Neuropsychiatric Presentations due to Traumatic Brain Injury in Cognitively Normal Older Adults

2020 ◽  
Author(s):  
Jahnavi Mundluru ◽  
Abdul Subhan ◽  
Tsz Wai Bentley Lo ◽  
Nathan Churchill ◽  
Luis Fornazzari ◽  
...  
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitively Normal

Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults

2021 ◽  
Author(s):  
Breton M. Asken ◽  
William G. Mantyh ◽  
Renaud La Joie ◽  
Amelia Strom ◽  
Kaitlin B. Casaletto ◽  
...  
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Amyloid Burden ◽  
Clinically Normal
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