Physical activity, socialization and reading in the elderly over the age of seventy: What is the relation with cognitive decline? Evidence from “The Treviso Longeva (TRELONG) study”

Abstract Background Few previous cohorts have studied the different type of physical activities and the degree of cognitive decline. The objective of this work was to analyze the leisure, domestic and professional activities with mild and moderate cognitive disorders in older people living in community. Methods The study used data from the longitudinal and observational study, FrèLE (FRagility: Longitudinal Study of Expressions). The collected data included: socio-demographic variables, lifestyle, and health status (frailty, comorbidities, cognitive status, depression). Cognitive decline was assessed by using: MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment). MoCA was used with two cut-offs (26 and 17) so as to define mild and moderate cognitive disorders Physical activity was assessed by the PASE (Physical Activity Scale for the Elderly), structured in three sections: leisure, domestic and professional activities. Spline and proportional hazards regression models (Cox) were used to estimate the risk of cognitive disorders. Results At baseline, 1623 participants were included and the prevalence of cognitive disorders was 6.9% (MMSE) and 7.2% (MoCA), mild cognitive disorders was 71.3%. The mean age was 77 years, and 52% of the participants were women. After a 2 years long follow-up, we found 6.9% (MMSE) and 6% (MoCA) cognitive disorders on participants. Analyses showed that domestic activities were associated to cognitive decline (HR = 0.52 [0.28-0.94] for MMSE and HR = 0.48 [0.28-0.80] for MoCA). No association were found with leisure and professional activities, and no spline were significant with mild cognitive disorders. Conclusions Analysis showed a relationship between cognitive disorders and type of physical activity, thanks to the use of specific questionnaire of elderly and two global test of cognition. These findings will contribute to the debate on the beneficial effects of physical activity on cognition. Key messages This work allowed to compare two test of cognition and their link with physical activity. It contributes to the debate on the beneficial effects of physical activity on cognition. The work allowed us to see the effect of the different types of physical activity and the impact of the statistical method on the results.

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[P2-569]: SELF-REPORTED SLEEP DISTURBANCES AND COGNITIVE DECLINE IN THE ELDERLY: ATTENUATING THE RISK BY PHYSICAL ACTIVITY

Alzheimer s & Dementia ◽

10.1016/j.jalz.2017.06.1228 ◽

2017 ◽

Vol 13 (7S_Part_17) ◽

pp. P863-P864

Author(s):

Min-Kuang Tsai ◽

Jen-Hau Chen ◽

Jeng-Min Chiou ◽

Ta-Fu Chen ◽

Ya-Fang Chen ◽

...

Keyword(s):

Physical Activity ◽

Cognitive Decline ◽

Sleep Disturbances ◽

The Elderly

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Association of Physical Activity and APOE Genotype With Longitudinal Cognitive Change in Early PD

Neurology ◽

10.1212/wnl.0000000000011852 ◽

2021 ◽

pp. 10.1212/WNL.0000000000011852

Author(s):

Ryul Kim ◽

Sangmin Park ◽

Dallah Yoo ◽

Jin-Sun Jun ◽

Beomseok Jeon

Keyword(s):

Physical Activity ◽

Cognitive Decline ◽

Significant Interaction ◽

Apoe Genotype ◽

The Elderly ◽

Cognitive Change ◽

Cognitive Changes ◽

Progression Markers ◽

Ε4 Allele

Objective:To determine whether greater physical activity could modify the negative association of APOE ε4 with longitudinal cognitive changes in early Parkinson’s disease (PD) and to uncover the disease-specific mechanism for explaining such benefits of physical activity.Methods:We used data from the Parkinson’s Progression Markers Initiative cohort. Because self-reported physical activity, measured by the Physical Activity Scale of the Elderly, was initiated at 2 years after enrollment, this longitudinal analysis was based on assessments performed at years 2, 3, and 4. Cognitive function was measured annually with the Montreal Cognitive Assessment (MoCA). Dopamine transporter (DAT) imaging was performed at years 2 and 4. We assessed the interactive associations between physical activity and the APOE ε4 allele on the longitudinal changes in MoCA scores and striatal DAT activities.Results:A total of 173 early PD patients (age 63.3±10.0 years; 27% APOE ε4 carriers) were included. The APOE ε4 allele showed a steeper rate of cognitive decline than the non-APOE ε4 allele (estimate -1.33; 95% CI, -2.12 to -0.47; p=0.002). However, there was a significant interaction between physical activity and APOE ε4, such that higher physical activity was related to slower APOE ε4-related cognitive decline (estimate 0.007; 95% CI, 0.003 to 0.011; p=0.001). No significant interaction was found between physical activity and the APOE ε4 allele regarding the change in striatal DAT activities.Conclusion:Increased physical activity attenuated APOE ε4-related vulnerability to early cognitive decline in PD patients. This protective effect did not appear to be mediated by striatal dopaminergic function.Classification of evidence:This study provides Class II evidence that increased physical activity was associated with decreased APOE ε4-related early cognitive decline in PD patients.

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P3-398: Physical Activity, Potential Confounders and Cognitive Decline in the Elderly

Alzheimer s & Dementia ◽

10.1016/j.jalz.2016.06.2064 ◽

2016 ◽

Vol 12 ◽

pp. P1002-P1002

Author(s):

Min-Kuang Tsai ◽

Jen-Hau Chen ◽

Chien-Cheng Jung ◽

Jeng-Min Chiou ◽

Ta-Fu Chen ◽

...

Keyword(s):

Physical Activity ◽

Cognitive Decline ◽

The Elderly

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O1-02-02: Preventing cognitive decline in the elderly through physical activity in midlife

Alzheimer s & Dementia ◽

10.1016/j.jalz.2011.05.232 ◽

2011 ◽

Vol 7 ◽

pp. S95-S96

Author(s):

Angela Clifford ◽

Eef Hogervorst ◽

Stephan Bandelow

Keyword(s):

Physical Activity ◽

Cognitive Decline ◽

The Elderly

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Physical activity in the elderly: A planned behaviour?

PsycEXTRA Dataset ◽

10.1037/e547922012-224 ◽

2003 ◽

Author(s):

Fabio Lucidi Lucidi ◽

Caterina Grano ◽

Alberto Cei

Keyword(s):

Physical Activity ◽

The Elderly ◽

Planned Behaviour

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Physical Activity Scale for the Elderly

PsycTESTS Dataset ◽

10.1037/t08150-000 ◽

1993 ◽

Author(s):

Richard A. Washburn ◽

Kevin W. Smith ◽

Alan M. Jette ◽

Carol A. Janney

Keyword(s):

Physical Activity ◽

The Elderly ◽

Activity Scale ◽

Physical Activity Scale

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Informant Questionnaire on Cognitive Decline in the Elderly--Farsi Version

PsycTESTS Dataset ◽

10.1037/t73529-000 ◽

2019 ◽

Author(s):

Mahshid Foroughan ◽

Zahra Jafari ◽

Ida Ghaemmagham Farahani ◽

Vahid Rashedi

Keyword(s):

Cognitive Decline ◽

The Elderly ◽

Farsi Version

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Forms of physical activity of the elderly

European Journal of Clinical and Experimental Medicine ◽

10.15584/ejcem.2020.3.10 ◽

2020 ◽

Vol 18 (3) ◽

pp. 221-228

Author(s):

Piotr Czarnecki ◽

◽

Justyna Podgórska-Bednarz ◽

Lidia Perenc ◽

◽

...

Keyword(s):

Physical Activity ◽

Elderly People ◽

Population Aging ◽

Human Life ◽

Good Health ◽

The Elderly ◽

Polish Society ◽

Central Statistical ◽

Key Phrases ◽

The Impact

Introduction. Physical activity is known to be an important factor influencing health throughout human life. This issue has become crucial for public health due to the aging of the population in both developed and developing countries. Aim. is to present a literature review on the forms of physical activity undertaken by the elderly, as well as on issues related to physical activity and the population aging. Material and methods. The study was prepared on the basis of a review of Polish and foreign literature. The following databases and data sources were used: EBSCO, ScienceDirect and Google Scholar. An additional source of data were the websites of the Central Statistical Office. Strictly defined key phrases were used during the collection of literature. The work has been divided into thematic subsections on the aging of the society, the impact of physical activity on health and the main topic, i.e. forms of physical activity selected by the elderly. Analysis of the literature. The number of elderly people in Polish society has increased by almost 3.7 million over three decades. Therefore, an important topic is prophylaxis aimed at increasing the number of days in good health, largely covering the broadly understood activation of the elderly. The available data indicate that only 12% of elderly people undertake physical activity once a week. The most common form of spending free time actively is walking (as many as 73% of people in this population declare this form of physical activity in one of the presented studies). Conclusion. Organized forms of physical activity are undertaken much less frequently by the analyzed age group mainly due to financial limitations and limited availability of sports infrastructure.

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Differences in physical function and metabolic syndrome risk factors according to the level of physical activity in elderly Korean men: a pilot study

10.31083/jomh.v17i1.200 ◽

2020 ◽

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Metabolic Syndrome ◽

Physical Function ◽

Vigorous Physical Activity ◽

Density Lipoprotein ◽

The Elderly ◽

Berg Balance Scale ◽

Lower Percentage ◽

Mineral Density

Background and objective: Managing the decrease in physical function in the elderly is a major task in aging societies globally. Here, we aimed to compare the physical function and metabolic syndrome (MetS) risk factors according to levels of physical activity (PA). Material and methods: We measured PA in 77 elderly Korean men (74.21 ± 6.26 years old) with an accelerometer and recorded body composition, physical function, and MetS-related risk factors. Participants were divided into three groups based on daily moderate-vigorous physical activity (MVPA): low (under 60 min), middle (60-120 min), and high (over 120 min). The groups were compared using a one-way analysis of variance and the Scheffe post hoc test. Odds ratios (OR) were calculated by logistic regression analysis. Results: Signiﬁcant differences were found between the groups for sedentary behavior time (P < 0.001), light PA (P < 0.05), moderate PA (P < 0.001), vigorous PA (P < 0.05), and total energy expenditure (P < 0.001). The high PA group showed a signiﬁcantly lower percentage of body fat and fat mass and higher muscle mass than did the low and middle PA groups (P < 0.05). The 6-min walk test was signiﬁcantly better in the high PA group than in the low and middle PA groups (P < 0.05). Grip strength and the Berg balance scale were also signiﬁcantly better in the high PA group (P < 0.05). Bone mineral density (BMD) and high-density lipoprotein cholesterol (HDL-C) were signiﬁcantly higher in the high PA group than in the low PA group (P < 0.05). Systolic blood pressure (SBP) was signiﬁcantly higher in the middle PA group than in the low PA group (P < 0.05). Participants with more than three MetS criteria showed an OR of 0.09 (95% conﬁdence interval 0.01-0.82) in the high PA group as compared with the low PA group (P < 0.05). Conclusions: Moderate-vigorous physical activity of more than 120 min daily showed better physical function and lower OR of MetS than did lower MVPA levels in elderly Korean men.

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