nDepressive symptoms as a predictor of memory decline in older adults: a longitudinal study using the dual change score model.

Author(s):  
Mariana Teles ◽  
Dingjing Shi
GeroPsych ◽  
2020 ◽  
Vol 33 (4) ◽  
pp. 235-244
Author(s):  
Boo Johansson ◽  
Marcus Praetorius Björk ◽  
Valgeir Thorvaldsson

Abstract. In 1987, we administered a subjective memory questionnaire to 143 40-year-old men, and 30 years later 67 of them again responded to the same questionnaire at age 70. At the follow-up, we also instructed participants to answer the questionnaire in the same manner as they thought they did at age 40 and to perform a picture recognition and a public event test. We employed confirmatory factor analysis to model a latent subjective memory construct. A single-factor solution provided acceptable model fit to data (χ2(12) = 9.33, p = .68; χ2(12) = 10.48, p = .57) and a decent reliability at both ages for the subjective memory measurements (omega = .82 and .93, respectively). Our longitudinal invariance testing revealed only a partial weak invariance. We also fitted a latent change-score model to the data. As expected, participants on average rated their memory as poorer at age 70 than at 40. Those who reported better overall health and less anxiety reported less memory decline up to age 70. Notably, this was also the case for those who rated memory as worse at age 40. Higher stress and depression at age 70, however, were associated with worse subjective memory already at age 40. The correspondences between memory ratings and tests were low. The correlation between the subjective memory factors at age 40 and 70 was 0.58, while the correlation between the memory factor at age 70 and the retrospective subjective memory factor was 0.87. Our findings suggest that subjective memory is quite consistent, and that we are inclined to preserve the continuity of our own memory functioning over the adult lifespan.


2021 ◽  
Author(s):  
Tibor Zingora ◽  
Sylvie Graf ◽  
Martina Hrebickova ◽  
Jaroslav Tocik ◽  
David Lacko ◽  
...  

In the COVID-19 pandemic, it is vital to identify factors increasing behaviors that limit the transmission of COVID-19 (i.e., anti-COVID-19 behavior) and factors protecting against the negative consequences of the pandemic on societies (i.e., prejudice). A simultaneous investigation of a change in anti-COVID behavior and prejudice during the pandemic is essential because some factors (e.g., fear of COVID-19) could increase both outcomes, whilst other factors (e.g., norms in anti-COVID behavior or intergroup contact in prejudice) could bring desirable changes in one outcome without negatively affecting the other. In a three-wave longitudinal study (NT1 = 4275) in five European countries from April to October 2020, we employed a latent change score model to distinguish between intra- and inter-individual changes in anti-COVID-19 behavior and prejudice. On the intra-individual level, anti-COVID-19 behavior was increased by anti-COVID-19 norms; and prejudice against migrants from the Middle East was influenced by positive and negative direct and mass-media intergroup contact.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Beatriz Olaya ◽  
Maria Victoria Moneta ◽  
Martin Bobak ◽  
Josep Maria Haro ◽  
Panayotes Demakakos

Abstract Background We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers. Methods We analysed data from 4372 participants aged 50–64 and 3005 persons aged 65–79 years old from the English Longitudinal Study of Ageing who were repeatedly evaluated every 2 years and had six interviews of a 10-year follow-up. We measured the following baseline risk factors: diabetes, hypertension, smoking, physical inactivity and obesity to derive a cardiovascular risk factor score (CVRFs). Adjusted linear mixed effect regression models were estimated to determine the association between number of CVFRs and six repeated measurements of verbal memory scores, separately for middle-aged and older adults. Results CVRFs was not significantly associated with memory at baseline. CVFRs was significantly associated with memory decline in middle-aged (50-64y), but not in older (65-79y) participants. This association followed a dose-response pattern with increasing number of CVFRs being associated with greater cognitive decline. Comparisons between none versus some CVRFs yielded significant differences (p < 0.05). Conclusions Our findings confirm that the effect of cumulative CVRFs on subsequent cognitive deterioration is age-dependent. CVRFs are associated with cognitive decline in people aged 50–64 years, but not in those aged ≥65 years. Although modest, the memory decline associated with accumulation of cardiovascular risk factors in midlife may increase the risk of late-life dementia.


1992 ◽  
Vol 7 (2) ◽  
pp. 185-193 ◽  
Author(s):  
Joy L. Taylor ◽  
Terry P. Miller ◽  
Jared R. Tinklenberg

2020 ◽  
Author(s):  
Mariana Teles ◽  
Dingjing Shi

Background: the direction of the longitudinal association between depression and cognition remains a topic of intense debate. A unidirectional association where depression impacts the change in cognition (or vice-versa) and a bidirectional association where the trajectories of both dimensions affect each other lead to different clinical implications. Method: this study aimed to investigate the directionality of the depression-cognition association in a sample of 2,057 older adults aged between 60 to 99 years old from the Virginia Cognitive Aging Project (VCAP). We used the bivariate dual change score model to investigate the association between five cognitive domains (memory, speed, reasoning, space, and vocabulary) and three dimensions of depression (somatic, depressed affect, and positive affect) throughout five measurement points with an average interval of 2.5 years between the assessments. Three directions were tested for each pair of variables: two unidirectional models and one bidirectional model. Results: a unidirectional effect in which depression at time t predicts change in cognition presented the best data fit for most of the cognitive domains. One significant causal effect was found: depressed affect (DA) at time t significantly predicted the change in memory with a negative association, that is, higher levels of DA at baseline predicted a worse performance on memory over time (γDep = -0.32881; SE = 0.17; p &lt; 0.05). Conclusions: our findings support a unidirectional association with depression predicting change for most of the cognitive domains tested. Higher levels of DA in older adults predicted an accelerated decline in memory.


2020 ◽  
Vol 34 (6) ◽  
pp. 654-666 ◽  
Author(s):  
Erika J. Laukka ◽  
Ylva Köhncke ◽  
Goran Papenberg ◽  
Laura Fratiglioni ◽  
Lars Bäckman

2020 ◽  
Author(s):  
Francesca Farina ◽  
Marc Patrick Bennett ◽  
James William Griffith ◽  
Bert Lenaert

Evidence concerning the impact of fear of memory decline on health-related outcomes is limited. To determine the relationship between fear-avoidance of memory decline, quality of life and subjective memory in older adults using a novel scale to measure fear of memory decline. Sixty-seven older adults (59-81 years) completed a 23-item self-report questionnaire designed to capture experiential, cognitive and behavioral components of fear of memory decline, known as the fear and avoidance of memory decline (FAM) scale. Memory performance was assessed using the Wechsler Memory Scale (WMS-IV) and the Memory Failures Scale (MFS). General anxiety was assessed using the Depression, Anxiety and Stress Scales (DASS) and the Geriatric Anxiety Inventory (GAI). Quality of life was assessed using the Older Person’s Quality of Life scale (OPQOL-35). The FAM scale demonstrated good reliability and validity. Three latent factors were observed including: (1) fear-avoidance, (2) problematic beliefs and (3) resilience. After adjusting for age, education, memory performance and general anxiety, higher fear-avoidance predicted lower quality of life (p=.021) and increased memory failures (p=.022). Increased fear of memory decline predicts lower quality of life and subjective memory failures in healthy older adults. Based on these findings, we propose a preliminary fear-avoidance model that explains the development and maintenance of dementia-related functional disability in terms of psychological processes.


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