The impact of bile leakage on long-term prognosis in primary liver cancers after hepatectomy: A propensity-score-matched study

Abstract Background Concomitant tricuspid regurgitation (TR) is a common finding in mitral regurgitation (MR). Transcatheter repair (TMVR) is a favorable treatment option in patients at elevated surgical risk. To date, evidence on long-term prognosis and the prognostic impact of TR after TMVR is limited. Methods Long-term survival data of patients undergoing isolated edge-to-edge repair from June 2010 to March 2018 (combinations with other forms of TMVR or tricuspid valve therapy excluded) were analyzed in a retrospective monocentric study. TR severity was categorized and the impact of TR on survival was analysed. Results Overall, 606 patients [46.5% female, 56.4% functional MR (FMR)] were enrolled in this study. TR at baseline was categorized severe/medium/mild/no or trace in 23.2/34.3/36.3/6.3% of the cases. At 30-day follow-up, improvement of at least one TR-grade was documented in 34.9%. Severe TR at baseline was identified as predictor of 1-year survival [65.2% vs. 77.0%, p = 0.030; HR for death 1.68 (95% CI 1.12–2.54), p = 0.013] and in FMR-patients also regarding long-term prognosis [adjusted HR for long-term mortality 1.57 (95% CI 1.00–2.45), p = 0.049]. Missing post-interventional reduction of TR severity was predictive for poor prognosis, especially in the FMR-subgroup [1-year survival: 92.9% vs. 78.3%, p = 0.025; HR for death at 1-year follow-up 3.31 (95% CI 1.15–9.58), p = 0.027]. While BNP levels decreased in both subgroups, TR reduction was associated with improved symptomatic benefit (NYHA-class-reduction 78.6 vs. 65.9%, p = 0.021). Conclusion In this large study, both, severe TR at baseline as well as missing secondary reduction were predictive for impaired long-term prognosis, especially in patients with FMR etiology. TR reduction was associated with increased symptomatic benefit. Graphic abstract

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Surgical Loupe at 4.0× Magnification in Pancreaticoduodenectomy—Does It Affect the Surgical Outcomes? A Propensity Score–Matched Study

Surgical Innovation ◽

10.1177/1553350618812322 ◽

2018 ◽

Vol 26 (2) ◽

pp. 201-208

Author(s):

Mohamed El Shobary ◽

Ayman El Nakeeb ◽

Ahmad Sultan ◽

Mahmoud Abd El Wahab Ali ◽

Mohamed El Dosoky ◽

...

Keyword(s):

Postoperative Complications ◽

Propensity Score ◽

Hospital Stay ◽

Pancreatic Fistula ◽

Surgical Outcomes ◽

Operative Time ◽

Postoperative Pancreatic Fistula ◽

Tube Removal ◽

Matched Study ◽

The Impact

Background. There is paucity of data about the impact of using magnification on rate of pancreatic leak after pancreaticoduodenectomy (PD). The aim of this study was to show the impact of using magnifying surgical loupes 4.0× EF (electro-focus) on technical performance and surgical outcomes of PD. Patients and Method. This is a propensity score–matched study. Thirty patients underwent PD using surgical loupes at 4.0× magnification (Group A), and 60 patients underwent PD using the conventional method (Group B). The primary outcome was postoperative pancreatic fistula. Secondary outcomes included operative time, intraoperative blood loss, postoperative complications, mortality, and hospital stay. Results. The total operative time was significantly longer in the loupe group ( P = .0001). The operative time for pancreatic reconstruction was significantly longer in the loupe group ( P = .0001). There were no significant differences between both groups regarding hospital stay, time to oral intake, total amount of drainage, and time of nasogastric tube removal. Univariate and multivariate analyses demonstrated 3 independent factors of development of postoperative pancreatic fistula: pancreatic duct <3 mm, body mass index >25, and soft pancreas. Conclusion. Surgical loupes 4.0× added no advantage in surgical outcomes of PD with regard to improvement of postoperative complications rate or mortality rate.

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The impact of acetylcoline-provoked coronary artery spasm on long-term prognosis of previous coronary revascularization

Atherosclerosis ◽

10.1016/j.atherosclerosis.2017.06.167 ◽

2017 ◽

Vol 263 ◽

pp. e49

Author(s):

Eun Mi Lee ◽

Hong Seog Seo ◽

Kyeong Ho Yun ◽

Cheol Ung Choi ◽

Jin Won Kim ◽

...

Keyword(s):

Coronary Artery ◽

Coronary Revascularization ◽

Coronary Artery Spasm ◽

Long Term Prognosis ◽

The Impact

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The impact of older age on long term survival in living donor liver transplantation: A propensity score matching analysis

Asian Journal of Surgery ◽

10.1016/j.asjsur.2021.11.061 ◽

2021 ◽

Author(s):

Ali Avanaz ◽

Volkan Doğru ◽

Abdullah Kisaoglu ◽

Vural Taner Yilmaz ◽

Demet Sarıdemir Ünal ◽

...

Keyword(s):

Liver Transplantation ◽

Propensity Score ◽

Living Donor ◽

Living Donor Liver Transplantation ◽

Donor Liver ◽

Term Survival ◽

Donor Liver Transplantation ◽

Propensity Score Matching Analysis ◽

The Impact

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Results of surgical treatment of moderate ischemic mitral regurgitation: A propensity analysis

10.22541/au.160813504.44743381/v1 ◽

2020 ◽

Author(s):

Jiyoung Lee ◽

Kan Kajimoto ◽

Taira Yamamoto ◽

Kenji Kuwaki ◽

Yuki Kamikawa ◽

...

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

Surgical Treatment ◽

Mitral Valve ◽

Propensity Score ◽

Artery Bypass ◽

Long Term Outcomes ◽

Artery Disease ◽

The Impact

Background and Aim of the Study: Ischemic mitral valve regurgitation (IMR) in patients undergoing coronary artery bypass grafting (CABG) is associated with worse long-term outcomes. The aim of this study was to assess the impact of mitral valve repair with CABG in patients with moderate IMR. Method: This observational study enrolled 3,215 consecutive patients from the Juntendo CABG registry with moderate IMR and multivessel coronary artery disease who underwent CABG between 2002 and 2017. The CABG alone and CABG with mitral valve surgery (MVs) groups were compared. The propensity score was calculated for each patient. Long-term all-cause death, cardiac death, and major adverse cardiac and cerebrovascular events (MACCEs) were compared between the two groups. Results: A total of 101 patients who underwent CABG had moderate IMR in our database. Propensity score matching selected 40 pairs for final analysis. MVs was associated with increased risks of postoperative atrial fibrillation, blood transfusion, and longer hospitalization. There were no differences between the two groups in long-term outcomes, including all-cause mortality, cardiac mortality, and the incidence of MACCEs. Conclusions: Surgical treatment of moderate IMR combined with CABG was as safe as CABG alone, with no differences in long-term outcomes. Further studies are needed to determine the effects of MVs in patients with moderate IMR and severe coronary artery disease.

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The impact of tumor location on the biological and oncological differences of colon cancer: Multi-institutional propensity score-matched study

The American Journal of Surgery ◽

10.1016/j.amjsurg.2018.07.005 ◽

2019 ◽

Vol 217 (1) ◽

pp. 46-52 ◽

Cited By ~ 3

Author(s):

Tomokazu Kishiki ◽

Kristine Kuchta ◽

Hiroyoshi Matsuoka ◽

Koichiro Kojima ◽

Nobuyoshi Asou ◽

...

Keyword(s):

Colon Cancer ◽

Propensity Score ◽

Tumor Location ◽

Matched Study ◽

The Impact

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Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study

World Journal of Surgery ◽

10.1007/s00268-019-04927-x ◽

2019 ◽

Vol 43 (6) ◽

pp. 1594-1603 ◽

Cited By ~ 12

Author(s):

Chetana Lim ◽

Chady Salloum ◽

Antonella Tudisco ◽

Claudio Ricci ◽

Michael Osseis ◽

...

Keyword(s):

Liver Resection ◽

Propensity Score ◽

Laparoscopic Liver Resection ◽

Long Term Outcomes ◽

Short And Long Term ◽

Matched Study

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Long-term prognosis of patients withJ-wave syndrome

Heart ◽

10.1136/heartjnl-2019-315007 ◽

2019 ◽

Vol 106 (4) ◽

pp. 299-306

Author(s):

Tsukasa Kamakura ◽

Tetsuji Shinohara ◽

Kenji Yodogawa ◽

Nobuyuki Murakoshi ◽

Hiroshi Morita ◽

...

Keyword(s):

High Amplitude ◽

Long Term Study ◽

St Segment ◽

History Of ◽

Provocation Testing ◽

Long Term Prognosis ◽

Electrocardiographic Parameters ◽

The Impact

ObjectiveLimited data are currently available regarding the long-term prognosis of patients with J-wave syndrome (JWS). The aim of this study was to investigate the long-term prognosis of patients with JWS and identify predictors of the recurrence of ventricular fibrillation (VF).MethodsThis was a multicentre retrospective study (seven Japanese hospitals) involving 134 patients with JWS (Brugada syndrome (BrS): 85; early repolarisation syndrome (ERS): 49) treated with an implantable cardioverter defibrillator. All patients had a history of VF. All patients with ERS underwent drug provocation testing with standard and high intercostal ECG recordings to rule out BrS. The impact of global J waves (type 1 ECG or anterior J waves and inferolateral J waves in two or more leads) on the prognosis was evaluated.ResultsDuring the 91±66 months of the follow-up period, 52 (39%) patients (BrS: 37; ERS: 15) experienced recurrence of VF. Patients with BrS and ERS with global J waves showed a significantly higher incidence of VF recurrence than those without (BrS: log-rank, p=0.014; ERS: log-rank, p=0.0009). The presence of global J waves was a predictor of VF recurrence in patients with JWS (HR: 2.16, 95% CI 1.21 to 3.91, p=0.0095), while previously reported high-risk electrocardiographic parameters (high-amplitude J waves ≥0.2 mV and J waves associated with a horizontal or descending ST segment) were not predictive of VF recurrence.ConclusionsThis multicentre long-term study showed that the presence of global J waves was associated with a higher incidence of VF recurrence in patients with JWS.

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Association of hyperlipidaemia with 5-year survival after hospitalisation for acute myocardial infarction: a propensity score matched analysis

Open Heart ◽

10.1136/openhrt-2019-001163 ◽

2020 ◽

Vol 7 (1) ◽

pp. e001163

Author(s):

Mohammed Yousufuddin ◽

Ye Zhu ◽

Ruaa Al Ward ◽

Jessica Peters ◽

Taylor Doyle ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Propensity Score ◽

Primary Objective ◽

Life Years ◽

Statin Prescription ◽

Statin Adherence ◽

The Impact

ObjectivesThe primary objective was to examine the association between hyperlipidaemia (HLP) and 5-year survival after incident acute myocardial infarction (AMI). The secondary objectives were to assess the effect of HLP on survival to discharge across patient subgroups, and the impact of statin prescription, intensity and long-term statin adherence on 5-year survival.MethodsRetrospective cohort study of 7071 patients hospitalised for AMI at Mayo Clinic from 2001 through 2011. Of these, 2091 patients with HLP (age (mean±SD) 69.7±13.5) were propensity score matched to 2091 patients without HLP (age 70.6±14.2).ResultsIn matched patients, HLP was associated with higher rate of survival to discharge than no HLP (95% vs 91%; log-rank <0.0001). At year 5, the adjusted HR for all-cause mortality in patients with HLP versus no HLP was 0.66 (95% CI 0.58–0.74), and patients with prescription statin versus no statin was 0.24 (95% CI 0.21 to 0.28). The mean survival was 0.35 year greater in patients with HLP than in those with no HLP (95% CI 0.25 to 0.46). Patients with HLP gained on an average 0.17 life year and those treated with statin 0.67 life year at 5 years after AMI. The benefit of concurrent HLP was consistent across study subgroups.ConclusionsIn patients with AMI, concomitant HLP was associated with increased survival and a net gain in life years, independent of survival benefit from statin therapy. The results also reaffirm the role of statin prescription, intensity and adherence in reducing the mortality after incident AMI.

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