Hemoglobin concentration, hematocrit and red blood cell count predict major adverse cardiovascular events in patients with familial hypercholesterolemia

Author(s):  
Martine Paquette ◽  
Sophie Bernard ◽  
Alexis Baass
2019 ◽  
Vol 21 (93) ◽  
pp. 15-20
Author(s):  
S. Goncharov

The article presents the results of the research concerning the morphological changes in the blood of the predatory fish species (perch, pike and zander) сaused by nematodical parasitic disease – eustrongylidosis. The research has been conducted in 2014–2018. It has been found that in the blood of perch with eustrongylidosis the hemoglobin and the red-blood-cell count decreased by 6.87 and 42.11 respectively, the white-blood-cell count increased by 8.95%; the basophils and pseudobasophils count – by 129.17%; the eosinophils and pseudoeosinophils count – by 131%; the number of band and segmented neutrophils increased by 27.92 and 37.5% respectively; the young neutrophils were not registered; the number of monocytes – by 16.34%; the lymphocyte count reduced by 3.27% in contrast with a fish that were not sick with the disease. The significant morphological changes in the blood of pikes with eustrongylidosis were also observed. Thus, the hemoglobin concentration, the number of red blood cells and lymphocytes decreased by 11.02, 26.32 and 3.16% respectively. The total leukocytes count increased by 22.02%; the basophils and pseudobasophils count – by 114%; the eosinophils and pseudoiesinophils count – by 95.83%; the number of band and segmented neutrophils increased by 1.71 and 46.72% respectively; a reduction of the young neutrophil granulocytes amount to 26% was noted; the number of monocytes of the blood increased by 25.83% in contrast with pikes that were not affected by the eustrongylidosis. A reduction of the red-blood-cell and lymphocytes amount, as well as hemoglobin concentration – to 30.05, 4.4 та 6.3% respectively was observed in hematological screening of the blood of zanders. The amount of leukocytes in the blood of infested fish increased by 10.6%; the basophils and pseudobasophils count – by 69.23%; the eosinophils and pseudoeosinophils count – by 116.67%; the number of band and segmented neutrophils increased by 15.58 and 23.27% respectively; the elevation of the number of young neutrophils to 5.75% was registered; the number of monocytes increased by 17.46% in contrast with zanders that were not infested.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Alejandro Gil-Betacur ◽  
Carmen Yulieth Mantilla-Gutiérrez ◽  
Jaiberth Antonio Cardona-Arias

AbstractThe effects of platelet donation by apheresis on different parameters of the erythrogram are still unclear. The objective was to meta-analyze the effect of plateletpheresis on hematocrit, hemoglobin, and erythrocyte count, with a systematic review with random effects meta-analysis of the mean difference. The PRISMA guidelines were considered, as well as 133 search strategies on four different databases. Reproducibility was guaranteed and methodological quality was evaluated. Heterogeneity was evaluated with Galbraith and DerSimonian-Laird’s, publication bias with a funnel plot and a Begg’s test, sensitivity analysis and a cumulative meta-analysis were also conducted. Eighteen (18) articles were included, 17 evaluated the effects on hematocrit in 2,564 donors; 13 on hemoglobin in 1,640 donors; and 4 on red blood cell count in 243 donors. A decrease of 2.26% (CI95% = 2.11–2.41) was observed in hematocrit, of 0.80 g/dL (CI95% = 0.75–0.86) in hemoglobin and −0.21 × 1012/L (CI95% = −0.13; −0.29) in red blood cell count. Plateletpheresis has a negative effect on the erythrogram parameters, explained by blood loss in the kits used for the procedure and cell lysis. Such evidence is relevant to secure the efficiency and safety of the procedure, improve selection processes or determine the number of donations that can be performed without affecting donors’ health.


2002 ◽  
Vol 57 (3) ◽  
pp. 177-185 ◽  
Author(s):  
Paolo Emilio PUDDU ◽  
Mariapoala LANTI ◽  
Alessandro MENOTTI ◽  
Mario MANCINI ◽  
Alberto ZANCHETTI ◽  
...  

2019 ◽  
Vol 33 (5) ◽  
pp. 6001-6010 ◽  
Author(s):  
Andreas Lodberg ◽  
Bram C. J. Eerden ◽  
Bianca Boers‐Sijmons ◽  
Jesper Skovhus Thomsen ◽  
Annemarie Brüel ◽  
...  

1979 ◽  
Vol 27 (6) ◽  
pp. 913 ◽  
Author(s):  
JL Barnett ◽  
RA How ◽  
WF Humphreys

Age, sex and seasonal related changes in body weight and blood parameters were determined for T caninus and T. vulpecula, whose distribution overlapped in part of the study area. In T. caninus age-related changes occurred in body weight, mean plasma glucose and protein concentrations and haematocrit. Seasonal changes occurred in plasma glucose and protein concentrations, haemoglobin concentration and red blood cell count. There were sexual dimorphisms in haematocrit, haemoglobin concentration and red blood cell count in both species; the mean values were greater in males. T. vulpecula also exhibited a sexual dimorphism in body weight (males > females). The only seasonal change in T. vulpecula was in haemoglobin concentration. Comparison of the species as adults showed that T. caninus had higher mean levels of body weight, haematocrit and haemoglobin concentration, while plasma lipid concentration and red blood cell counts were greater in T vulpecula. These species differences may be a reflection of the diets of the two species. In addition the measured parameters showed greater seasonal variation in T. caninus, a K-selected species, than in T. vulpecula, which is more r-selected.


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