scholarly journals Increased serum 2-oxoglutarate associated with high myocardial energy expenditure and poor prognosis in chronic heart failure patients

2014 ◽  
Vol 1842 (11) ◽  
pp. 2120-2125 ◽  
Author(s):  
Ping-An Chen ◽  
Zhi-Hao Xu ◽  
Yu-Li Huang ◽  
Yi Luo ◽  
Ding-Ji Zhu ◽  
...  
2021 ◽  
Vol 7 ◽  
Author(s):  
Wilson Matthew Raffaello ◽  
Joshua Henrina ◽  
Ian Huang ◽  
Michael Anthonius Lim ◽  
Leonardo Paskah Suciadi ◽  
...  

Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.


2011 ◽  
Vol 18 (3) ◽  
pp. 165-172 ◽  
Author(s):  
Zhongwei Cheng ◽  
Kongbo Zhu ◽  
Taibo Chen ◽  
Peng Gao ◽  
Kang’an Cheng ◽  
...  

2003 ◽  
Vol 2 (1) ◽  
pp. 23-24
Author(s):  
A SCARDOVI ◽  
C COLETTA ◽  
N ASPROMONTE ◽  
A SESTILI ◽  
M RENZI ◽  
...  

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