Absence of mitochondrial DNA methylation in mouse oocyte maturation, aging and early embryo development

2019 ◽  
Vol 513 (4) ◽  
pp. 912-918 ◽  
Author(s):  
Li-Hua Fan ◽  
Zhen-Bo Wang ◽  
Qian-Nan Li ◽  
Tie-Gang Meng ◽  
Ming-Zhe Dong ◽  
...  
Zygote ◽  
2018 ◽  
Vol 26 (4) ◽  
pp. 261-269
Author(s):  
Xia-Guang Duan ◽  
Zai-Qing Huang ◽  
Chun-Guang Hao ◽  
Xiao-Jun Zhi ◽  
Xiao-Bing Qi ◽  
...  

SummaryPropofol is a intravenous anaesthetic most commonly used in ultrasound oocyte retrieval. We studied if the use of propofol had an effect on mouse oocyte maturation, pregnancy, childbirth and progeny and investigated the correlation between propofol side effects and reproductive performance in mice. There was no statistical difference in mating, pregnancy, childbirth, litter size, the number of stillbirths and survival between each group (P>0.05). Propofol also had no effect on polar body extrusion in oocyte maturation as well as on pronucleus formation and, subsequently, early embryo development (P>0.05). An increased concentration of propofol had no effect on this result, although propofol at more than 0.01 mg/ml reduced polar body extrusion. Different concentrations of propofol had no effect on oocyte culture in vitro, pronucleus formation and early embryo development.


2014 ◽  
Vol 37 (2) ◽  
pp. 126-132 ◽  
Author(s):  
Xiao-Xin Dai ◽  
Xing Duan ◽  
Hong-Lin Liu ◽  
Xiang-Shun Cui ◽  
Nam-Hyung Kim ◽  
...  

2011 ◽  
Vol 85 (Suppl_1) ◽  
pp. 334-334
Author(s):  
Cai-Xia Yang ◽  
Zhi-Qiang Du ◽  
Elane C. Wright ◽  
Ben Selman ◽  
Max F. Rothschild ◽  
...  

2020 ◽  
Vol 21 (10) ◽  
pp. 3581
Author(s):  
Anthony Estienne ◽  
Adeline Brossaud ◽  
Maxime Reverchon ◽  
Christelle Ramé ◽  
Pascal Froment ◽  
...  

Some evidence shows that body mass index in humans and extreme weights in animal models, including avian species, are associated with low in vitro fertilization, bad oocyte quality, and embryo development failures. Adipokines are hormones mainly produced and released by white adipose tissue. They play a key role in the regulation of energy metabolism. However, they are also involved in many other physiological processes including reproductive functions. Indeed, leptin and adiponectin, the most studied adipokines, but also novel adipokines including visfatin and chemerin, are expressed within the reproductive tract and modulate female fertility. Much of the literature has focused on the physiological and pathological roles of these adipokines in ovary, placenta, and uterine functions. The purpose of this review is to summarize the current knowledge regarding the involvement of leptin, adiponectin, visfatin, and chemerin in the oocyte maturation, fertilization, and embryo development in both mammals and birds.


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