Effect of ldhA gene deletion on the metabolism of Escherichia coli based on gene expression, enzyme activities, intracellular metabolite concentrations, and metabolic flux distribution

Metabolite Concentrations ◽

Ldha Gene

Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments

Journal of Biotechnology ◽

10.1016/j.jbiotec.2005.09.016 ◽

2006 ◽

Vol 122 (2) ◽

pp. 254-266 ◽

Cited By ~ 55

Author(s):

Mai Li ◽

Pei Yee Ho ◽

Shanjing Yao ◽

Kazuyuki Shimizu

Keyword(s):

Escherichia Coli ◽

Metabolic Flux Analysis ◽

Enzyme Activities ◽

Metabolic Flux ◽

Gene Knockout ◽

Flux Analysis ◽

13C Labeling ◽

Metabolic flux analysis of pykF gene knockout Escherichia coli based on 13C-labeling experiments together with measurements of enzyme activities and intracellular metabolite concentrations

Applied Microbiology and Biotechnology ◽

10.1007/s00253-003-1357-9 ◽

2003 ◽

Vol 63 (4) ◽

pp. 407-417 ◽

Cited By ~ 99

Author(s):

K. Al Zaid Siddiquee ◽

M. J. Arauzo-Bravo ◽

K. Shimizu

Keyword(s):

Escherichia Coli ◽

Metabolic Flux Analysis ◽

Enzyme Activities ◽

Metabolic Flux ◽

Gene Knockout ◽

Flux Analysis ◽

13C Labeling ◽

Metabolic flux analysis of Escherichia coli K-12 based on 13C-labeling experiments with measurement of intracellular metabolite concentrations for carbon source-limited and nitrogen source-limited chemostat cultures

Metabolic Engineering ◽

10.1016/s1096-7176(03)00045-4 ◽

2003 ◽

Author(s):

J Zhu

Keyword(s):

Escherichia Coli ◽

Carbon Source ◽

Nitrogen Source ◽

Metabolic Flux Analysis ◽

Metabolic Flux ◽

Flux Analysis ◽

Chemostat Cultures ◽

Metabolite Concentrations ◽

K 12

Investigation on the Metabolic Regulation of pgi gene knockout Escherichia coli by Enzyme Activities and Intracellular Metabolite Concentrations

Malaysian Journal of Microbiology ◽

10.21161/mjm.220605 ◽

2006 ◽

Author(s):

Aini, A. R.* ◽

Shirai, Y. ◽

Hassan, M. A. ◽

Shimizu, K.

Keyword(s):

Escherichia Coli ◽

Enzyme Activities ◽

Metabolic Regulation ◽

Gene Knockout ◽

Effect of ppc gene knockout on the metabolism of Escherichia coli in view of gene expressions, enzyme activities and intracellular metabolite concentrations

Applied Microbiology and Biotechnology ◽

10.1007/s00253-004-1567-9 ◽

2004 ◽

Cited By ~ 2

Author(s):

L. Peng ◽

K. Shimizu

Keyword(s):

Escherichia Coli ◽

Enzyme Activities ◽

Gene Knockout ◽

Gene Expressions ◽

Effect of fadR gene knockout on the metabolism of Escherichia coli based on analyses of protein expressions, enzyme activities and intracellular metabolite concentrations

Enzyme and Microbial Technology ◽

10.1016/j.enzmictec.2005.07.019 ◽

2006 ◽

Vol 38 (3-4) ◽

pp. 512-520 ◽

Cited By ~ 21

Author(s):

Lifeng Peng ◽

Kazuyuki Shimizu

Keyword(s):

Escherichia Coli ◽

Enzyme Activities ◽

Gene Knockout ◽

Protein Expressions ◽

Metabolic flux distribution and thermodynamic analysis of green fluorescent protein production in recombinant Escherichia coli: The effect of carbon source and CO 2 partial pressure

Biotechnology and Bioprocess Engineering ◽

10.1007/s12257-013-0277-5 ◽

2013 ◽

Vol 18 (6) ◽

pp. 1049-1061 ◽

Cited By ~ 3

Author(s):

R. Axayácatl González-García ◽

E. Ines Garcia-Peña ◽

Edgar Salgado-Manjarrez ◽

Juan S. Aranda-Barradas

Keyword(s):

Escherichia Coli ◽

Green Fluorescent Protein ◽

Carbon Source ◽

Protein Production ◽

Metabolic Flux ◽

Flux Distribution ◽

Fluorescent Protein ◽

Green Fluorescent Protein Production ◽

Green Fluorescent

Impact Analysis of Gene Deletion on the Metabolic Flux Distribution of E.coli and on Its Flux-Backbone: Genome-Scale Simulation Approach

2008 2nd International Conference on Bioinformatics and Biomedical Engineering ◽

10.1109/icbbe.2008.111 ◽

2008 ◽

Author(s):

Zixiang Xu ◽

Xie Jianming ◽

Xinan Yang ◽

Sun Xiao

Keyword(s):

Metabolic Flux ◽

Gene Deletion ◽

Impact Analysis ◽

Flux Distribution ◽

Simulation Approach ◽

Genome Scale

Prediction of Metabolic Flux Distribution from Gene Expression Data Based on the Flux Minimization Principle

PLoS ONE ◽

10.1371/journal.pone.0112524 ◽

2014 ◽

Vol 9 (11) ◽

pp. e112524 ◽

Cited By ~ 24

Author(s):

Hyun-Seob Song ◽

Jaques Reifman ◽

Anders Wallqvist

Keyword(s):

Gene Expression ◽

Gene Expression Data ◽

Metabolic Flux ◽

Flux Distribution ◽

Expression Data ◽

Minimization Principle ◽

Flux Minimization

Effect of Glucose Analog Supplementation on Metabolic Flux Distribution in Anaerobic Chemostat Cultures of Escherichia coli

Metabolic Engineering ◽

10.1006/mben.1999.0141 ◽

2000 ◽

Vol 2 (2) ◽

pp. 149-154 ◽

Cited By ~ 8

Author(s):

Susana J. Berrı́os-Rivera ◽

Yea-Ting Yang ◽

George N. Bennett ◽

Ka-Yiu San

Keyword(s):

Escherichia Coli ◽

Metabolic Flux ◽

Flux Distribution ◽

Chemostat Cultures ◽

Effect Of Glucose