The effect of 3-hydroxybutyrate on the in vitro differentiation of murine osteoblast MC3T3-E1 and in vivo bone formation in ovariectomized rats

Biomaterials ◽  
2007 ◽  
Vol 28 (20) ◽  
pp. 3063-3073 ◽  
Author(s):  
Yan Zhao ◽  
Bing Zou ◽  
Zhenyu Shi ◽  
Qiong Wu ◽  
Guo-Qiang Chen
Keyword(s):  
Bone Formation ◽  
Ovariectomized Rats ◽  
In Vitro Differentiation ◽  
In Vivo Bone Formation

ONO-1301 Enhances in vitro Osteoblast Differentiation and in vivo Bone Formation Induced by Bone Morphogenetic Protein

Spine ◽  
2018 ◽  
Vol 43 (11) ◽  
pp. E616-E624 ◽  
Author(s):  
Sadaaki Kanayama ◽  
Takashi Kaito ◽  
Kazuma Kitaguchi ◽  
Hiroyuki Ishiguro ◽  
Kunihiko Hashimoto ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Morphogenetic Protein ◽  
Osteoblast Differentiation ◽  
Morphogenetic Protein ◽  
In Vivo Bone Formation

In vitro and in vivo bone formation potential of surface calcium phosphate-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds

2016 ◽  
Vol 30 ◽  
pp. 319-333 ◽  
Author(s):  
Patrina S.P. Poh ◽  
Dietmar W. Hutmacher ◽  
Boris M. Holzapfel ◽  
Anu K. Solanki ◽  
Molly M. Stevens ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Formation ◽  
Bioactive Glass ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
Formation Potential ◽  
In Vivo Bone Formation

scholarly journals Study of in Vitro and in Vivo Bone Formation in Composite Cryogels and the Influence of Electrical Stimulation

2015 ◽  
Vol 11 (11) ◽  
pp. 1325-1336 ◽  
Author(s):  
Ruchi Mishra ◽  
Deepak Bushan Raina ◽  
Mea Pelkonen ◽  
Lars Lidgren ◽  
Magnus Tägil ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Bone Formation ◽  
In Vivo Bone Formation

Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation

Gene Therapy ◽  
2021 ◽  
Author(s):  
Gileade P. Freitas ◽  
Helena B. Lopes ◽  
Alann T. P. Souza ◽  
Maria Paula O. Gomes ◽  
Georgia K. Quiles ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Formation ◽  
Osteogenic Potential ◽  
In Vivo Bone Formation

Adenoviral BMP-2 Gene Transfer in Mesenchymal Stem Cells: In Vitro and in Vivo Bone Formation on Biodegradable Polymer Scaffolds

2002 ◽  
Vol 292 (1) ◽  
pp. 144-152 ◽  
Author(s):  
Kris Partridge ◽  
Xuebin Yang ◽  
Nicholas M.P. Clarke ◽  
Yasunori Okubo ◽  
Kazuhisa Bessho ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Gene Transfer ◽  
Bone Formation ◽  
Biodegradable Polymer ◽  
Polymer Scaffolds ◽  
In Vivo Bone Formation

scholarly journals Effect of diosgenin, a steroidal sapogenin, on the rat skeletal system.

2016 ◽  
Vol 63 (2) ◽  
Author(s):  
Joanna Folwarczna ◽  
Maria Zych ◽  
Barbara Nowińska ◽  
Maria Pytlik ◽  
Magdalena Bialik ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Formation ◽  
Cancellous Bone ◽  
Compact Bone ◽  
Estrogen Deficiency ◽  
Ovariectomized Rats ◽  
Skeletal System ◽  
Steroidal Sapogenin

Diosgenin is a steroidal sapogenin present in fenugreek and Dioscorea spp. as glycosides (saponins). Diosgenin has already been reported to inhibit osteoclastogenesis and to stimulate osteogenic activity of osteoblastic cells in vitro, and to exert some antiosteoporotic effects in rats in vivo. The aim of the present study was to investigate the effects of diosgenin administration on the skeletal system of rats with normal estrogen level and with estrogen deficiency induced by bilateral ovariectomy. The experiments were carried out on 3-month-old non-ovariectomized and ovariectomized Wistar rats, divided into control rats and rats receiving diosgenin (50 mg/kg p.o. daily) for 4 weeks. Serum bone turnover markers, bone mass and mineralization, histomorphometric parameters and mechanical properties were studied. Diosgenin improved some investigated parameters in both non-ovariectomized and ovariectomized rats, in which estrogen deficiency induced osteoporotic changes. Diosgenin increased compact bone formation and probably inhibited cancellous bone resorption, which led to improvement of mechanical properties of compact and cancellous bone. In conclusion, this in vivo study demonstrated that diosgenin may be one of sparse compounds increasing bone formation.

Effect of surface alkali-based treatment of titanium implants on ability to promote in vitro mineralization and in vivo bone formation

2017 ◽  
Vol 57 ◽  
pp. 511-523 ◽  
Author(s):  
Winston A. Camargo ◽  
Shinji Takemoto ◽  
Jan Willem Hoekstra ◽  
Sander C.G. Leeuwenburgh ◽  
John A. Jansen ◽  
...  
Keyword(s):  
Bone Formation ◽  
Titanium Implants ◽  
In Vitro Mineralization ◽  
In Vivo Bone Formation ◽  
Effect Of Surface
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