The effect of nanometric surface texture on bone contact to titanium implants in rabbit tibia

Titanium Grade 4 (G4) is the most commonly used material for dental implants due to its excellent biocompatibility and mechanical properties. However, titanium implants require a rough surface that can increase the biomechanical potential of implant–bone contact and affect protein adsorption speed. In this work, the effect of sandblasting of the Ti G4 surface on the long-term corrosion resistance in artificial saliva of pH = 7.4 at 37 °C was studied. The X-ray diffraction (XRD) single-{hkl} sin2ψ method was used to measure the sandblasted Ti residual stress. In vitro corrosion resistance tests were conducted for 21 days using the open circuit potential method, polarization curves, and electrochemical impedance spectroscopy. Using the Kelvin scanning probe, the electron work function was determined. Analysis of the obtained results showed an improvement in the corrosion resistance of the sandblasted Ti G4 compared to Ti with the machine surface. The increase in corrosion resistance was related to the residual compressive stress of 324.7 MPa present in the sandblasted Ti surface. Sandblasting caused plastic deformation of the Ti surface, which resulted in the improvement in mechanical properties, as evidenced by the increase in the hardness of the sandblasted Ti compared to Ti with the machine surface.

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Removal Torque Analysis of Implants in Rabbit Tibia After Topical Application of Simvastatin Gel

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-11-00128 ◽

2014 ◽

Vol 40 (1) ◽

pp. 53-59 ◽

Cited By ~ 4

Author(s):

Fatima Neves Faraco-Schwed ◽

Luiz Macedo Mangueira ◽

Joao Vitor Albuquerque Ribeiro ◽

Alexsandro Da Silva Antao ◽

Jamil Awad Shibli

Keyword(s):

Topical Application ◽

Topical Administration ◽

Titanium Implants ◽

Removal Torque ◽

Implant Placement ◽

Group I ◽

Torque Wrench ◽

Rabbit Tibia ◽

Torque Analysis ◽

Torque Values

The aim of this study was to evaluate the effects of topical application of simvastatin gel (7.5 mg) on the removal torque of titanium implants in the rabbit tibia. A total of 32 surgeries were performed on 16 New Zealand rabbits for the placement of 2 implants in 1 tibia of each rabbit. Only 1 of the surgical defects was injected with 30 mg/mL of simvastatin gel before implant placement. The initial torque was set at 20 N.cm, and removal torque testing was performed 28 and 56 days postoperatively with a Tonishi torque wrench. Surgical defects were divided into 4 groups: group IG-28 (test, 28 days), group IG-56 (test, 56 days), group I-28 (control, 28 days), and group I-56 (control, 56 days). Removal torque values were higher in group IG-56 than in groups IG-28, I-28, and I-56 (P < .05). Groups IG-28, I-28, and I-56 showed similar values (P > .05). Removal torque force increased under the influence of simvastatin, indicating that topical administration of a 7.5-mg dose of simvastatin gel is effective in improving the torque force required to remove implants inserted in the rabbit tibia.

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Bone responses to rough titanium implants coated with biomimetic Ca-P in rabbit tibia

Journal of Biomedical Materials Research Part B Applied Biomaterials ◽

10.1002/jbm.b.31355 ◽

2009 ◽

Vol 90B (2) ◽

pp. 857-863 ◽

Cited By ~ 9

Author(s):

Fuming He ◽

Guoli Yang ◽

Xiaoxiang Wang ◽

Shifang Zhao

Keyword(s):

Titanium Implants ◽

Rabbit Tibia

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Effect of the long-term administration of Cyclosporine A on bone healing around osseointegrated titanium implants: A histomorphometric study in the rabbit tibia

Microscopy Research and Technique ◽

10.1002/jemt.22894 ◽

2017 ◽

Vol 80 (9) ◽

pp. 1000-1008 ◽

Cited By ~ 8

Author(s):

Rafael Scaf de Molon ◽

Celso Eduardo Sakakura ◽

Rafael Silveira Faeda ◽

Rafael Sartori ◽

Daniel Palhares ◽

...

Keyword(s):

Cyclosporine A ◽

Bone Healing ◽

Titanium Implants ◽

Histomorphometric Study ◽

Rabbit Tibia ◽

Term Administration

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Morphological and dimensional changes after barrier removal in bone formed beyond the skeletal borders at titanium implants. A kinetic study in the rabbit tibia.

Clinical Oral Implants Research ◽

10.1034/j.1600-0501.1997.080205.x ◽

1997 ◽

Vol 8 (2) ◽

pp. 103-116 ◽

Cited By ~ 23

Author(s):

Lars Rasmusson ◽

Lars Sennerby ◽

Dan Lundgren ◽

Sture Nyman

Keyword(s):

Kinetic Study ◽

Titanium Implants ◽

Dimensional Changes ◽

Rabbit Tibia ◽

Barrier Removal

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The Effects of a Static Magnetic Field on Bone Formation Around a Sandblasted, Large-Grit, Acid-Etched–Treated Titanium Implant

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-11-00101 ◽

2013 ◽

Vol 39 (S1) ◽

pp. 248-255 ◽

Cited By ~ 15

Author(s):

Richard Leesungbok ◽

Su-Jin Ahn ◽

Suk-Won Lee ◽

Geon-Ho Park ◽

Joo-Sung Kang ◽

...

Keyword(s):

Bone Formation ◽

Titanium Implant ◽

Titanium Implants ◽

Histomorphometric Analysis ◽

Contact Ratio ◽

Neodymium Magnet ◽

Significant Difference ◽

Rabbit Tibia ◽

Group 3 ◽

The Mean

The purpose of this study was to compare the bone formation around commercial sandblasted, large-grit, acid-etched (SLA)–treated titanium implants with or without a neodymium magnet in a rabbit tibia through histomorphometric analysis. Commercial SLA-treated implants with or without neodymium magnets were placed in 10 rabbits. After incising the flat part of the rabbit's tibia and installation of the specimens of titanium implants, the nonmagnet group was stitched without magnet insertion. On the other hand, the magnet group was inserted with neodymium magnet, fixed with pattern resin, and stitched. At 3 and 6 weeks after surgery, the animals were sacrificed, and the specimens were obtained. Undecalcified specimens were prepared for histomorphometric analysis of the bone-to-implant contact ratio (BIC) and bone volume (BV). The histomorphometric findings of the cortical bone showed that the mean BVs of the magnet group (3 weeks, 75.99%; 6 weeks, 82.94%) were higher than those of the nonmagnet group (3 weeks, 74.58%; 6 weeks, 78.75%), but there were no significant differences between the 2 groups (P > .05). In the marrow bone, the mean BICs of the magnet group (3 weeks, 10.36%; 6 weeks, 10.41%) were higher than those of the nonmagnet group (3 weeks, 6.41%; 6 weeks, 7.36%). After 3 weeks of installation, there was a significant difference between the 2 groups (P < .05). In rabbit tibia, the SLA-treated titanium implants with a neodymium magnet can trigger faster early peri-implant bone formation than those without a magnet.

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