Decreased Gamma-Band Auditory Steady State Response is Associated With Social Functional Impairment in Patients at Clinical High Risk for Schizophrenia

2020 ◽  
Vol 87 (9) ◽  
pp. S157-S158
Author(s):  
Jennifer Lepock ◽  
Sarah Ahmed ◽  
Romina Mizrahi ◽  
Michele Korostil ◽  
Gregory Light ◽  
...  
Keyword(s):  
Steady State ◽  
High Risk ◽  
Functional Impairment ◽  
Gamma Band ◽  
Steady State Response ◽  
Clinical High Risk ◽  
State Response ◽  
Auditory Steady State Response

Decreased Gamma Auditory Steady-State Response Is Associated With Impaired Real-World Functioning in Unmedicated Patients at Clinical High Risk for Psychosis

2020 ◽  
pp. 155005942098270
Author(s):  
Sarah Ahmed ◽  
Jennifer R. Lepock ◽  
Romina Mizrahi ◽  
R. Michael Bagby ◽  
Cory J. Gerritsen ◽  
...  
Keyword(s):  
Steady State ◽  
High Risk ◽  
Functional Impairment ◽  
Real World ◽  
Steady State Response ◽  
Clinical High Risk ◽  
State Response ◽  
Auditory Steady State Response ◽  
Gamma Synchrony ◽  
40 Hz

Aim Deficits in synchronous, gamma-frequency neural oscillations may contribute to schizophrenia patients’ real-world functional impairment and can be measured electroencephalographically using the auditory steady-state response (ASSR). Gamma ASSR deficits have been reported in schizophrenia patients and individuals at clinical high risk (CHR) for developing psychosis. We hypothesized that, in CHR patients, gamma ASSR would correlate with real-world functioning, consistent with a role for gamma synchrony deficits in functional impairment. Methods A total of 35 CHR patients rated on Global Functioning: Social and Role scales had EEG recorded while listening to 1-ms, 93-dB clicks presented at 40 Hz in 500-ms trains, in response to which 40-Hz evoked power and intertrial phase-locking factor (PLF) were measured. Results In CHR patients, lower 40-Hz PLF correlated with lower social functioning. Conclusions Gamma synchrony deficits may be a biomarker of real-world impairment at early stages of the schizophrenia disease trajectory.

The effect of selective attention on the gamma-band auditory steady-state response

2007 ◽  
Vol 420 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Patrick D. Skosnik ◽  
Giri P. Krishnan ◽  
Brian F. O’Donnell
Keyword(s):  
Steady State ◽  
Selective Attention ◽  
Gamma Band ◽  
Steady State Response ◽  
State Response ◽  
Auditory Steady State Response

scholarly journals Sensitivity of the gamma band auditory steady state response to linguistic features of a stimulus.

2010 ◽  
Vol 1 ◽  
pp. 40
Author(s):  
Jessamy Sara Norton-Ford ◽  
Siyi Deng ◽  
Ramesh Srinivasan ◽  
Mary Louise Kean
Keyword(s):  
Steady State ◽  
Gamma Band ◽  
Steady State Response ◽  
Significance Tests ◽  
Linguistic Features ◽  
State Response ◽  
Auditory Steady State Response ◽  
Eeg Data ◽  
Speech Envelope ◽  
Initial Results

Recent work has found differences in lateralization of gamma band auditory steady state response power (?-aSSR) in temporo-parietal areas to speech vs. non-speech stim- uli, based on differences in “meaningfulness” (Deng & Srinivasan, 2009). To investigate sensitivity of ?-aSSR to linguistic features of a stimulus, EEG data was collected from six participants in response to 40Hz amplitude-modulated speech, jabberwocky, reversed speech and spectrally-rotated (“unintelligible”) speech. Significance tests were conducted for the four conditions, within and across-hemisphere. Additionally, correlational analysis of stimulus speech envelope and EEG output will be conducted. Initial results indicate overall right-lateralization, and additional left-hemisphere distinction by condition.

scholarly journals Gamma-band auditory steady-state response after frontal tDCS: A double-blind, randomized, crossover study

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193422 ◽  
Author(s):  
Yoshiaki Miyagishi ◽  
Takashi Ikeda ◽  
Tetsuya Takahashi ◽  
Kiwamu Kudo ◽  
Hirofumi Morise ◽  
...  
Keyword(s):  
Steady State ◽  
Crossover Study ◽  
Gamma Band ◽  
Steady State Response ◽  
Double Blind ◽  
State Response ◽  
Auditory Steady State Response ◽  
Randomized Crossover Study

Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study

2019 ◽  
Vol 208 ◽  
pp. 467-469 ◽  
Author(s):  
Daisuke Koshiyama ◽  
Kenji Kirihara ◽  
Mariko Tada ◽  
Tatsuya Nagai ◽  
Mao Fujioka ◽  
...  
Keyword(s):  
Steady State ◽  
Plasma Levels ◽  
Exploratory Study ◽  
Gamma Band ◽  
Steady State Response ◽  
State Response ◽  
Auditory Steady State Response
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