Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study

2019 ◽  
Vol 208 ◽  
pp. 467-469 ◽  
Author(s):  
Daisuke Koshiyama ◽  
Kenji Kirihara ◽  
Mariko Tada ◽  
Tatsuya Nagai ◽  
Mao Fujioka ◽  
...  
2007 ◽  
Vol 420 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Patrick D. Skosnik ◽  
Giri P. Krishnan ◽  
Brian F. O’Donnell

2010 ◽  
Vol 1 ◽  
pp. 40
Author(s):  
Jessamy Sara Norton-Ford ◽  
Siyi Deng ◽  
Ramesh Srinivasan ◽  
Mary Louise Kean

Recent work has found differences in lateralization of gamma band auditory steady state response power (?-aSSR) in temporo-parietal areas to speech vs. non-speech stim- uli, based on differences in “meaningfulness” (Deng & Srinivasan, 2009). To investigate sensitivity of ?-aSSR to linguistic features of a stimulus, EEG data was collected from six participants in response to 40Hz amplitude-modulated speech, jabberwocky, reversed speech and spectrally-rotated (“unintelligible”) speech. Significance tests were conducted for the four conditions, within and across-hemisphere. Additionally, correlational analysis of stimulus speech envelope and EEG output will be conducted. Initial results indicate overall right-lateralization, and additional left-hemisphere distinction by condition.


PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193422 ◽  
Author(s):  
Yoshiaki Miyagishi ◽  
Takashi Ikeda ◽  
Tetsuya Takahashi ◽  
Kiwamu Kudo ◽  
Hirofumi Morise ◽  
...  

2002 ◽  
Vol 13 (05) ◽  
pp. 260-269 ◽  
Author(s):  
Barbara Cone-Wesson ◽  
John Parker ◽  
Nina Swiderski ◽  
Field Rickards

Two studies were aimed at developing the auditory steady-state response (ASSR) for universal newborn hearing screening. First, neonates who had passed auditory brainstem response, transient evoked otoacoustic emission, and distortion-product otoacoustic emission tests were also tested with ASSRs using modulated tones that varied in frequency and level. Pass rates were highest (> 90%) for amplitude-modulated tones presented at levels ≥ 69 dB SPL. The effect of modulation frequency on ASSR for 500- and 2000-Hz tones was evaluated in full-term and premature infants in the second study. Full-term infants had higher pass rates for 2000-Hz tones amplitude modulated at 74 to 106 Hz compared with pass rates for a 500-Hz tone modulated at 58 to 90 Hz. Premature infants had lower pass rates than full-term infants for both carrier frequencies. Systematic investigation of ASSR threshold and the effect of modulation frequency in neonates is needed to adapt the technique for screening.


2020 ◽  
pp. 155005942098270
Author(s):  
Sarah Ahmed ◽  
Jennifer R. Lepock ◽  
Romina Mizrahi ◽  
R. Michael Bagby ◽  
Cory J. Gerritsen ◽  
...  

Aim Deficits in synchronous, gamma-frequency neural oscillations may contribute to schizophrenia patients’ real-world functional impairment and can be measured electroencephalographically using the auditory steady-state response (ASSR). Gamma ASSR deficits have been reported in schizophrenia patients and individuals at clinical high risk (CHR) for developing psychosis. We hypothesized that, in CHR patients, gamma ASSR would correlate with real-world functioning, consistent with a role for gamma synchrony deficits in functional impairment. Methods A total of 35 CHR patients rated on Global Functioning: Social and Role scales had EEG recorded while listening to 1-ms, 93-dB clicks presented at 40 Hz in 500-ms trains, in response to which 40-Hz evoked power and intertrial phase-locking factor (PLF) were measured. Results In CHR patients, lower 40-Hz PLF correlated with lower social functioning. Conclusions Gamma synchrony deficits may be a biomarker of real-world impairment at early stages of the schizophrenia disease trajectory.


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