Portable and multiplexed lateral flow immunoassay reader based on SERS for highly sensitive point-of-care testing

2020 ◽  
Vol 168 ◽  
pp. 112524 ◽  
Author(s):  
Rui Xiao ◽  
Luchun Lu ◽  
Zhen Rong ◽  
Chongwen Wang ◽  
Yongjin Peng ◽  
...  
Keyword(s):  
Point Of Care ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Point Of Care Testing ◽  
Highly Sensitive

A glass fiber sheet-based electroosmotic lateral flow immunoassay for point-of-care testing

Lab on a Chip ◽  
2012 ◽  
Vol 12 (24) ◽  
pp. 5155 ◽  
Author(s):  
Yuriko Oyama ◽  
Toshihisa Osaki ◽  
Koki Kamiya ◽  
Ryuji Kawano ◽  
Tsutomu Honjoh ◽  
...  
Keyword(s):  
Glass Fiber ◽  
Point Of Care ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Point Of Care Testing ◽  
Fiber Sheet

scholarly journals A low-cost smartphone-based platform for highly sensitive point-of-care testing with persistent luminescent phosphors

Lab on a Chip ◽  
2017 ◽  
Vol 17 (6) ◽  
pp. 1051-1059 ◽  
Author(s):  
Andrew S. Paterson ◽  
Balakrishnan Raja ◽  
Vinay Mandadi ◽  
Blane Townsend ◽  
Miles Lee ◽  
...  
Keyword(s):  
Point Of Care ◽  
Low Cost ◽  
Test Strip ◽  
Lateral Flow ◽  
Point Of Care Testing ◽  
Flow Test ◽  
Highly Sensitive ◽  
Lateral Flow Test ◽  
Gated Imaging

Time-gated imaging on a smartphone of a lateral flow test strip run with persistent luminescent nanophosphors.

scholarly journals Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19

Biosensors ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 295
Author(s):  
Wesley Wei-Wen Hsiao ◽  
Trong-Nghia Le ◽  
Dinh Minh Pham ◽  
Hui-Hsin Ko ◽  
Huan-Cheng Chang ◽  
...  
Keyword(s):  
Point Of Care ◽  
Lateral Flow ◽  
Enzyme Linked Immunosorbent Assay ◽  
Laboratory Diagnostics ◽  
Rt Pcr ◽  
Point Of Care Testing ◽  
Specific Point ◽  
Recent Advances ◽  
Highly Sensitive ◽  
Polymerase Chain

The development of reliable and robust diagnostic tests is one of the most efficient methods to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, most laboratory diagnostics for COVID-19, such as enzyme-linked immunosorbent assay (ELISA) and reverse transcriptase-polymerase chain reaction (RT-PCR), are expensive, time-consuming, and require highly trained professional operators. On the other hand, the lateral flow immunoassay (LFIA) is a simpler, cheaper device that can be operated by unskilled personnel easily. Unfortunately, the current technique has some limitations, mainly inaccuracy in detection. This review article aims to highlight recent advances in novel lateral flow technologies for detecting SARS-CoV-2 as well as innovative approaches to achieve highly sensitive and specific point-of-care testing. Lastly, we discuss future perspectives on how smartphones and Artificial Intelligence (AI) can be integrated to revolutionize disease detection as well as disease control and surveillance.

scholarly journals Point of care testing evaluation of lateral flow immunoassay for diagnosis of Cryptococcus Meningitis in Kenya, 2017

2019 ◽  
Author(s):  
Lawrence Kirimi Gitonga ◽  
Waqo Gufu Boru ◽  
Arthur Kwena ◽  
Marybeth Maritim ◽  
Joyce Wamicwe ◽  
...  
Keyword(s):  
Point Of Care ◽  
Cross Sectional Study ◽  
Latex Agglutination ◽  
Capillary Blood ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Point Of Care Testing ◽  
Cross Sectional ◽  
India Ink ◽  
Cryptococcus Meningitis

Abstract Objectives: The objective of this study was to evaluate the performance of lateral flow immunoassay (LFA) against latex agglutination (LA), India ink and culture in point-of-care diagnosis of CM. We conducted a cross-sectional study among patients with suspected CM at Mbagathi Hospital, Nairobi, April-July 2017. Results: Of 124 capillary blood and serum and 99 cerebrospinal fluid (CSF) samples, the agreement between LFA and LA on serum was 94.4%, kappa (0.88), sensitivity (100%) and specificity (91%). LFA and LA on CSF, was 97.9%, kappa (0.96), sensitivity (100%) and specificity (96%). LFA and India ink was 96.9%, kappa (0.94), sensitivity (100%) and specificity (94.1%). On CSF culture, the agreement was 72.7%, kappa (0.43), sensitivity (100%) and specificity (64%). The agreement of LFA on capillary blood, serum and CSF was 100% with kappa (1.00), sensitivity and specificity of 100%

scholarly journals The Application of Lateral Flow Immunoassay in Point of Care Testing: A Review

2016 ◽  
Vol 8 (3) ◽  
Author(s):  
Kan Wang ◽  
Weijian Qin ◽  
Yafei Hou ◽  
Kun Xiao ◽  
Wenqiang Yan
Keyword(s):  
Point Of Care ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Point Of Care Testing

scholarly journals Lower Urine Tenofovir Concentrations among Individuals Taking Tenofovir Alafenamide versus Tenofovir Disoproxil Fumarate: Implications for Point-of-Care Testing

2021 ◽  
Author(s):  
Kelly A Johnson ◽  
Xin Niu ◽  
David V Glidden ◽  
Jose R Castillo-Mancilla ◽  
Jenna Yager ◽  
...  
Keyword(s):  
Tenofovir Disoproxil Fumarate ◽  
Point Of Care ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Directly Observed Therapy ◽  
Point Of Care Testing ◽  
Separate Point ◽  
Tenofovir Alafenamide ◽  
Adherence Monitoring ◽  
Therapy Studies

Abstract From directly-observed-therapy studies, urine tenofovir (TFV) levels were 74% lower when taking tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate. Urine TFV remains quantifiable across a range of TAF adherence patterns, but a separate point-of-care lateral flow immunoassay with a lower TFV threshold will be needed to support TAF adherence monitoring.

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