scholarly journals Neuroimage: A Novel Highly Efficient Tool for Image Processing of in vivo Neural Networks

2015 ◽  
Vol 108 (2) ◽  
pp. 472a
Author(s):  
Christian Heusinger ◽  
André Drews ◽  
Aune Koitmäe ◽  
Robert Blick
2003 ◽  
Vol 7 (5) ◽  
pp. 700-710 ◽  
Author(s):  
Florian Krötz ◽  
Cor de Wit ◽  
Hae-Young Sohn ◽  
Stefan Zahler ◽  
Torsten Gloe ◽  
...  

Author(s):  
U. Aebi ◽  
L.E. Buhle ◽  
W.E. Fowler

Many important supramolecular structures such as filaments, microtubules, virus capsids and certain membrane proteins and bacterial cell walls exist as ordered polymers or two-dimensional crystalline arrays in vivo. In several instances it has been possible to induce soluble proteins to form ordered polymers or two-dimensional crystalline arrays in vitro. In both cases a combination of electron microscopy of negatively stained specimens with analog or digital image processing techniques has proven extremely useful for elucidating the molecular and supramolecular organization of the constituent proteins. However from the reconstructed stain exclusion patterns it is often difficult to identify distinct stain excluding regions with specific protein subunits. To this end it has been demonstrated that in some cases this ambiguity can be resolved by a combination of stoichiometric labeling of the ordered structures with subunit-specific antibody fragments (e.g. Fab) and image processing of the electron micrographs recorded from labeled and unlabeled structures.


Author(s):  
Y.A. Hamad ◽  
K.V. Simonov ◽  
A.S. Kents

The paper considers general approaches to image processing, analysis of visual data and computer vision. The main methods for detecting features and edges associated with these approaches are presented. A brief description of modern edge detection and classification algorithms suitable for isolating and characterizing the type of pathology in the lungs in medical images is also given.


2021 ◽  
Vol 26 (1) ◽  
pp. 200-215
Author(s):  
Muhammad Alam ◽  
Jian-Feng Wang ◽  
Cong Guangpei ◽  
LV Yunrong ◽  
Yuanfang Chen

AbstractIn recent years, the success of deep learning in natural scene image processing boosted its application in the analysis of remote sensing images. In this paper, we applied Convolutional Neural Networks (CNN) on the semantic segmentation of remote sensing images. We improve the Encoder- Decoder CNN structure SegNet with index pooling and U-net to make them suitable for multi-targets semantic segmentation of remote sensing images. The results show that these two models have their own advantages and disadvantages on the segmentation of different objects. In addition, we propose an integrated algorithm that integrates these two models. Experimental results show that the presented integrated algorithm can exploite the advantages of both the models for multi-target segmentation and achieve a better segmentation compared to these two models.


Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4867
Author(s):  
Lu Chen ◽  
Hongjun Wang ◽  
Xianghao Meng

With the development of science and technology, neural networks, as an effective tool in image processing, play an important role in gradual remote-sensing image-processing. However, the training of neural networks requires a large sample database. Therefore, expanding datasets with limited samples has gradually become a research hotspot. The emergence of the generative adversarial network (GAN) provides new ideas for data expansion. Traditional GANs either require a large number of input data, or lack detail in the pictures generated. In this paper, we modify a shuffle attention network and introduce it into GAN to generate higher quality pictures with limited inputs. In addition, we improved the existing resize method and proposed an equal stretch resize method to solve the problem of image distortion caused by different input sizes. In the experiment, we also embed the newly proposed coordinate attention (CA) module into the backbone network as a control test. Qualitative indexes and six quantitative evaluation indexes were used to evaluate the experimental results, which show that, compared with other GANs used for picture generation, the modified Shuffle Attention GAN proposed in this paper can generate more refined and high-quality diversified aircraft pictures with more detailed features of the object under limited datasets.


Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2505
Author(s):  
Raheem Remtulla ◽  
Sanjoy Kumar Das ◽  
Leonard A. Levin

Phosphine-borane complexes are novel chemical entities with preclinical efficacy in neuronal and ophthalmic disease models. In vitro and in vivo studies showed that the metabolites of these compounds are capable of cleaving disulfide bonds implicated in the downstream effects of axonal injury. A difficulty in using standard in silico methods for studying these drugs is that most computational tools are not designed for borane-containing compounds. Using in silico and machine learning methodologies, the absorption-distribution properties of these unique compounds were assessed. Features examined with in silico methods included cellular permeability, octanol-water partition coefficient, blood-brain barrier permeability, oral absorption and serum protein binding. The resultant neural networks demonstrated an appropriate level of accuracy and were comparable to existing in silico methodologies. Specifically, they were able to reliably predict pharmacokinetic features of known boron-containing compounds. These methods predicted that phosphine-borane compounds and their metabolites meet the necessary pharmacokinetic features for orally active drug candidates. This study showed that the combination of standard in silico predictive and machine learning models with neural networks is effective in predicting pharmacokinetic features of novel boron-containing compounds as neuroprotective drugs.


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