Could We Improve the Quality of Superficial Brachytherapy in the Head and Neck Region Using Image-Based Treatment Planning?

Brachytherapy ◽  
2013 ◽  
Vol 12 ◽  
pp. S63
Author(s):  
Grzegorz Zwierzchowski ◽  
Grzegorz Bieleda ◽  
Janusz Skowronek
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Jens P.E. Schouten ◽  
Samantha Noteboom ◽  
Roland M. Martens ◽  
Steven W. Mes ◽  
C. René Leemans ◽  
...  

Abstract Background  Accurate segmentation of head and neck squamous cell cancer (HNSCC) is important for radiotherapy treatment planning. Manual segmentation of these tumors is time-consuming and vulnerable to inconsistencies between experts, especially in the complex head and neck region. The aim of this study is to introduce and evaluate an automatic segmentation pipeline for HNSCC using a multi-view CNN (MV-CNN). Methods The dataset included 220 patients with primary HNSCC and availability of T1-weighted, STIR and optionally contrast-enhanced T1-weighted MR images together with a manual reference segmentation of the primary tumor by an expert. A T1-weighted standard space of the head and neck region was created to register all MRI sequences to. An MV-CNN was trained with these three MRI sequences and evaluated in terms of volumetric and spatial performance in a cross-validation by measuring intra-class correlation (ICC) and dice similarity score (DSC), respectively. Results The average manual segmented primary tumor volume was 11.8±6.70 cm3 with a median [IQR] of 13.9 [3.22-15.9] cm3. The tumor volume measured by MV-CNN was 22.8±21.1 cm3 with a median [IQR] of 16.0 [8.24-31.1] cm3. Compared to the manual segmentations, the MV-CNN scored an average ICC of 0.64±0.06 and a DSC of 0.49±0.19. Improved segmentation performance was observed with increasing primary tumor volume: the smallest tumor volume group (<3 cm3) scored a DSC of 0.26±0.16 and the largest group (>15 cm3) a DSC of 0.63±0.11 (p<0.001). The automated segmentation tended to overestimate compared to the manual reference, both around the actual primary tumor and in false positively classified healthy structures and pathologically enlarged lymph nodes. Conclusion An automatic segmentation pipeline was evaluated for primary HNSCC on MRI. The MV-CNN produced reasonable segmentation results, especially on large tumors, but overestimation decreased overall performance. In further research, the focus should be on decreasing false positives and make it valuable in treatment planning.


2015 ◽  
Vol 24 (1) ◽  
pp. 99-103
Author(s):  
Peng Li ◽  
Sun Liyan ◽  
Xu Zhang ◽  
Rui-Hua Luo ◽  
Jin-Xing Qi ◽  
...  

2019 ◽  
Vol 35 (03) ◽  
pp. 256-259
Author(s):  
Zhe Hou ◽  
Patrick K. Lee

AbstractMedical tattooing has been used in various circumstances. In this review, the authors focus on the utilization of medical tattooing in the head and neck region as a minimally invasive alternative to corrective surgeries. It is mostly used to camouflage noticeable surgical scars on scalp, face, and perioral areas. Its use has also been described in cases of concealing depigmentation or hypopigmentation, hair loss, postirradiation telangiectasia, and congenital vascular malformation. These procedures are well-tolerated and safe. Its effects are long-lasting and satisfactory, leading to improvement in self-esteem and increased quality of life in treated patients. The limitations of medical tattooing in such uses include high technical requirement, color fading and alteration, unpredictable outcomes in scarred tissue, and potential cutaneous reactions. It also carries a risk of infection, albeit very low due to standardized sterilization process in a medical setting. The authors conclude that medical tattooing in the head and neck region may serve as an excellent option for patients who seek for cosmetic improvement in their deformities and/or discoloration but would prefer to avoid surgery.


Author(s):  
D’ Souza Jacob ◽  
Boyapati Raghu

AbstractSarcomas are malignant mesenchymal tumours. They are relatively uncommon in the head and neck region. They are diverse affecting both soft and hard tissues. Multiple histological subtypes are recognised. There is considerable variation in their behaviour and response to treatment, both in adults and children. Historically, poor outcomes are due to multiple reasons such as paucity of standardised treatment approaches and the complex anatomy of the head and neck region. Nevertheless, surgery plays a key part in the management of sarcomas, both from an ablative and reconstructive viewpoint. The modern reconstructive techniques have improved quality of life for those undergoing surgical ablation.


Author(s):  
Chavan Shrinivas

Introduction: Special senses are group of sensory organs that help us to connect with external environment by various modes of elements like sound, sight, touch and smell. Any damage to these organs though may not be physically handicapping but can affect the quality of life of any individual. Bullet injuries to the head and neck region are life-threatening and demand a detailed clinical examination and meticulous operative management due to the complexity of craniofacial anatomy. Head and neck region also house sense organs, but most of the time their functions are not properly assessed during the primary care provided in firearm injuries. The main aim of this study was – To study the long term effects of firearm injuries on special senses. To study the impact of these injuries on facial visage causing impairment on quality of life. To set a standard protocol that can be applied in such injuries for a bedside evaluation of sense organs of victims. Materials and Methods: The following study was conducted by the Department of Otorhinolaryngology & Head and Neck Surgery, Department of Forensic Medicine and Department of Community Medicine, at Grant Government Medical College and Sir JJ Group of Hospitals. A retrospective study of 532 patients who were victims of various firearm injuries in isolated civil incidents and terrorist attacks in Mumbai between January 1990 to July 2018. Institutional ethical clearance was obtained prior to initiating the study. Data regarding the patients were obtained from hospital records. Results: The age group which was most affected was between 20- 40 years i.e.; the working population of the country. Most of the patients were of the male gender, nearly 70.3%. The sense organ to be affected the most in these incidents was ear(55.2%) ,followed by eyes(39.3%) . Facial scar caused a significant social impact on the quality of life among females. Conclusion: This study aims to set a standard protocol in the post-critical phase in firearm injuries; giving priority to functions of sense organs and facial visage to ensure a good quality of life in the post-trauma period.


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