Chronic phenmetrazine treatment promotes D2 dopaminergic and α2-adrenergic receptor desensitization and alters phosphorylation of signaling proteins and local cerebral glucose metabolism in the rat brain

2021 ◽  
Vol 1761 ◽  
pp. 147387
Author(s):  
Bradley M. Keegan ◽  
Annie L. Dreitzler ◽  
Tammy Sexton ◽  
Thomas J.R. Beveridge ◽  
Hilary R. Smith ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Rat Brain ◽  
Adrenergic Receptor ◽  
Cerebral Glucose Metabolism ◽  
Signaling Proteins ◽  
Receptor Desensitization

Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brain

2012 ◽  
Vol 120 (3) ◽  
pp. 375-382 ◽  
Author(s):  
Nobuyuki Maruoka ◽  
Tetsuhito Murata ◽  
Naoto Omata ◽  
Hironori Mitsuya ◽  
Yasushi Kiyono ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Rat Brain ◽  
Cerebral Glucose Metabolism ◽  
Causal Mechanism

Cerebral glucose metabolism changes in rat brain upon forepaw electrical stimulation at different frequencies

Neuroreport ◽  
2015 ◽  
Vol 26 (4) ◽  
pp. 197-205
Author(s):  
Hun Nyun Kim ◽  
Won Beom Jung ◽  
Min Jung Kang ◽  
Geun Ho Im ◽  
Jung Hee Lee ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Glucose Metabolism ◽  
Rat Brain ◽  
Cerebral Glucose Metabolism

scholarly journals The Effect of Pentobarbital and Isoflurane on Glucose Metabolism in Thermally Injured Rat Brain

1990 ◽  
Vol 10 (5) ◽  
pp. 624-630 ◽  
Author(s):  
David P. Archer ◽  
Mary G. Elphinstone ◽  
Hanna M. Pappius
Keyword(s):  
Glucose Metabolism ◽  
Rat Brain ◽  
Cold Injury ◽  
Cerebral Glucose Metabolism ◽  
Quantitative Autoradiography ◽  
Injured Side ◽  
Subcortical Regions ◽  
Cortical Regions

The effect of pentobarbital and isoflurane on cerebral glucose metabolism (CMRglc) was studied in thermally injured rat brain using quantitative autoradiography. In awake lesioned animals, CMRglc in cortical regions ipsilateral to the injury was reduced to 50% of normal while little if any decrease was observed in contralateral cortical regions and subcortical regions bilaterally. Treatment of lesioned animals with pentobarbital or isoflurane further reduced CMRglc, but more in the hemisphere contralateral to the injury than on the injured side. Thus, the side-to-side difference in cortical CMRglc present in the awake lesioned animals was abolished by the anesthetics. The results support the hypothesis that CMRglc depression associated with a focal cold injury is functional in nature. Reduction of metabolism by anesthetics in functionally depressed brain is limited by the decrease in CMRglc associated with the injury.

Compartment analysis of cerebral glucose metabolism and in vitro glucose-metabolizing enzyme activities in the rat brain

1996 ◽  
Vol 706 (2) ◽  
pp. 267-272 ◽  
Author(s):  
Yasuomi Ouchi ◽  
Hidenao Fukuyama ◽  
Shigeru Matsuzaki ◽  
Masafumi Ogawa ◽  
Jun Kimura ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Rat Brain ◽  
Enzyme Activities ◽  
Cerebral Glucose Metabolism ◽  
Compartment Analysis ◽  
Metabolizing Enzyme
Sign in / Sign up

Export Citation Format

Share Document