Transcranial direct current stimulation (tDCS) of the right inferior frontal gyrus attenuates sustained fear

2017 ◽  
Vol 10 (2) ◽  
pp. 376 ◽  
Author(s):  
M.J. Herrmann ◽  
B. Simons ◽  
T. Polak
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Inferior Frontal Gyrus ◽  
Direct Current Stimulation ◽  
The Right

scholarly journals Comparison of repeated transcranial stimulation and transcranial direct-current stimulation on primary motor cortex excitability and inhibition: A pilot study

2018 ◽  
pp. 59-67 ◽  
Author(s):  
Vincent Cabibel ◽  
Makii Muthalib ◽  
Jérôme Froger ◽  
Stéphane Perrey
Keyword(s):  
Pilot Study ◽  
Motor Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Motor Cortex ◽  
Motor Evoked Potentials ◽  
High Definition ◽  
Direct Current Stimulation ◽  
Motor Cortex Excitability ◽  
The Right

Repeated transcranial magnetic stimulation (rTMS) is a well-known clinical neuromodulation technique, but transcranial direct-current stimulation (tDCS) is rapidly growing interest for neurorehabilitation applications. Both methods (contralesional hemisphere inhibitory low-frequency: LF-rTMS or lesional hemisphere excitatory anodal: a-tDCS) have been employed to modify the interhemispheric imbalance following stroke. The aim of this pilot study was to compare aHD-tDCS (anodal high-definition tDCS) of the left M1 (2 mA, 20 min) and LF-rTMS of the right M1 (1 Hz, 20 min) to enhance excitability and reduce inhibition of the left primary motor cortex (M1) in five healthy subjects. Single-pulse TMS was used to elicit resting and active (low level muscle contraction, 5% of maximal electromyographic signal) motor-evoked potentials (MEPs) and cortical silent periods (CSPs) from the right and left extensor carpi radialis muscles at Baseline, immediately and 20 min (Post-Stim-20) after the end of each stimulation protocol. LF-rTMS or aHD-tDCS significantly increased right M1 resting and active MEP amplitude at Post-Stim-20 without any CSP modulation and with no difference between methods. In conclusion, this pilot study reported unexpected M1 excitability changes, which most likely stems from variability, which is a major concern in the field to consider.

scholarly journals Modulating Observation-Execution-Related Motor Cortex Activity by Cathodal Transcranial Direct Current Stimulation

2019 ◽  
Vol 9 (5) ◽  
pp. 121 ◽  
Author(s):  
Fengxue Qi ◽  
Michael A. Nitsche ◽  
Volker R. Zschorlich
Keyword(s):  
Motor Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Movement Execution ◽  
Movement Observation ◽  
Direct Current Stimulation ◽  
Cohen’S D ◽  
Right Hand ◽  
The Right ◽  
Cohen's D

The aim of this randomized sham-controlled study was to examine the impact of cathodal transcranial direct current stimulation (ctDCS) of the primary motor cortex (M1) during movement observation on subsequent execution-related motor cortex activity. Thirty healthy participants received sham or real ctDCS (1 mA) over the left M1 for 10 minutes, respectively. The participants observed a video showing repeated button pressing tasks of the right hand during the sham or real ctDCS, followed by performance of these tasks by the right hand. Motor-evoked potentials (MEP) were recorded from the resting right first dorsal interosseous muscle before movement observation during the sham or real ctDCS, immediately after observation of actions, and after subsequent movement execution. The results of the ANOVA showed a significant main effect on the group (F1,28 = 4.60, p = 0.041) and a significant interaction between time and the group (F2,56 = 5.34, p = 0.008). As revealed by respective post hoc tests, ctDCS induced a significant reduction of MEP amplitudes in connection with movement observation (p = 0.026, Cohen’s d = 0.861) and after subsequent movement execution (p = 0.018, Cohen’s d = 0.914) in comparison with the sham stimulation. It is concluded that ctDCS during movement observation was effective in terms of modulating motor cortex excitability. Moreover, it subsequently influenced execution-related motor cortex activity. This indicates a possible application for rehabilitative treatment in syndromes with pathologically enhanced cortical activity.

Effects of Anodal Transcranial Direct Current Stimulation (atDCS) on Sentence Comprehension

2019 ◽  
Vol 25 (3) ◽  
pp. 331-335
Author(s):  
Jarrad A. G. Lum ◽  
Gillian M. Clark ◽  
Caitlyn M. Rogers ◽  
James D. Skalkos ◽  
Ian Fuelscher ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Sentence Comprehension ◽  
Inferior Frontal Gyrus ◽  
Reaction Times ◽  
Healthy Adults ◽  
Word Comprehension ◽  
Sham Stimulation ◽  
Direct Current Stimulation ◽  
Comprehension Task

AbstractObjectives: This study examined the effects of anodal transcranial direct current stimulation (a-tDCS) on sentence and word comprehension in healthy adults. Methods: Healthy adult participants, aged between 19 and 30 years, received either a-tDCS over the left inferior frontal gyrus (n=18) or sham stimulation (n=18). Participants completed sentence comprehension and word comprehension tasks before and during stimulation. Accuracy and reaction times (RTs) were recorded as participants completed both tasks. Results: a-tDCS was found to significantly decrease RT on the sentence comprehension task compared to baseline. There was no change in RT following sham stimulation. a-tDCS was not found to have a significant effect on accuracy. Also, a-tDCS did not affect accuracy or RTs on the word comprehension task. Conclusions: The study provides evidence that non-invasive anodal electrical stimulation can modulate sentence comprehension in healthy adults, at least compared to their baseline performance. (JINS, 2019, 25, 331–335)

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