Epigenetic genome-wide analysis identifies BEX1 as a candidate tumour suppressor gene in paediatric intracranial ependymoma

2014 ◽  
Vol 346 (1) ◽  
pp. 34-44 ◽  
Author(s):  
Katherine Karakoula ◽  
Thomas S. Jacques ◽  
Kim P. Phipps ◽  
William Harkness ◽  
Dominic Thompson ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Intracranial Ependymoma ◽  
Candidate Tumour Suppressor

scholarly journals RBM5/LUCA-15 — Tumour Suppression by Control of Apoptosis and the Cell Cycle?

2002 ◽  
Vol 2 ◽  
pp. 1885-1890 ◽  
Author(s):  
Mirna Mourtada-Maarabouni ◽  
Gwyn T. Williams
Keyword(s):  
Gene Locus ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Suppressor Activity ◽  
Tumour Suppression ◽  
Major Significance ◽  
Tumour Suppressor Activity ◽  
Alternatively Spliced ◽  
Candidate Tumour Suppressor

The candidate tumour suppressor gene, LUCA-15, maps to the lung cancer tumour suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts, which have been shown to function as regulators of apoptosis, a fact that may have a major significance in tumour regulation. This review highlights evidence that implicates the LUCA-15 locus in the control of apoptosis and cell proliferation, and reports observations that significantly strengthen the case for tumour suppressor activity by this gene.

BRD7 is a candidate tumour suppressor gene required for p53 function

2010 ◽  
Vol 12 (4) ◽  
pp. 380-389 ◽  
Author(s):  
Jarno Drost ◽  
Fiamma Mantovani ◽  
Francesca Tocco ◽  
Ran Elkon ◽  
Anna Comel ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Candidate Tumour Suppressor

scholarly journals Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer

2006 ◽  
Vol 95 (10) ◽  
pp. 1419-1423 ◽  
Author(s):  
C Rimkus ◽  
M Martini ◽  
J Friederichs ◽  
R Rosenberg ◽  
D Doll ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prognostic Significance ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Candidate Tumour Suppressor

Analysis of Losses of Heterozygosity of the Candidate Tumour Suppressor Gene DMBT1 in Melanoma Resection Specimens

Oncology ◽  
2002 ◽  
Vol 63 (2) ◽  
pp. 166-172 ◽  
Author(s):  
M. Deichmann ◽  
J. Mollenhauer ◽  
B. Helmke ◽  
M. Thome ◽  
W. Hartschuh ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Candidate Tumour Suppressor

Mutations in the candidate tumour suppressor gene FLJ12973 on chromosome 15q15 are rare in colorectal cancer

2003 ◽  
Vol 196 (1) ◽  
pp. 65-67 ◽  
Author(s):  
Christina Fleischmann ◽  
Stephen Bevan ◽  
James C Neil ◽  
Anne Terry ◽  
Richard S Houlston
Keyword(s):  
Colorectal Cancer ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Candidate Tumour Suppressor
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