1-Year Follow-Up of Urban Underserved Congestive Heart Failure Patients through Web-Based Telemedicine Monitoring System

2006 ◽  
Vol 12 (6) ◽  
pp. S72
Author(s):  
Mohammed A. Kashem ◽  
Marie T. Droogan ◽  
William P. Santamore ◽  
Joyce W. Wald ◽  
Robert C. Cross ◽  
...  
2021 ◽  
Author(s):  
Yikeber Abebaw Moyehodie ◽  
Kasim Mohammed Yesuf ◽  
Adem Aragaw Sied ◽  
Bezanesh Melese Masresha

Abstract Background: Globally, heart failure is a rapidly growing public health issue with an estimated prevalence of >37.7 million individuals. It is a shared chronic phase of cardiac functional impairment secondary to many etiologies. The main purpose of this study was to identify factors that affect the longitudinal changes of pulse rate and survival endpoints, time-to default among Congestive Heart Failure Patients in Felege- Hiwot Referral Hospital, Bahir Dar, Ethiopia.Methods: Hospital based retrospective studies were conducted among 302 congestive heart failure patients who were 15 years old or older and who were on treatment follow-up from the first February 2016 to thirty-one December 2018 in Felege-Hiwot Referral Hospital, Bahir Dar, Ethiopia. First, data were analyzed using linear mixed model and survival models separately, and then the joint models of both sub-models were analyzed by linked their shared unobserved random effects using a shared parameter model. Results: Out of the total 302 CHF treatment followers, 103 (34.1%) of the patients were defaulting from treatment. The mean pulse rate of female and male patients was 87.25 and 90.20, respectively. Averagely 51.12 % of blood in the left ventricle is pushed out with each heartbeat. The results for separate and joint models were quite similar to each other but not identical. However, the estimated association parameter (α) in the joint model is (HR=1.0311, 95%CI: 1.0033,1.0597, P=0.0278), providing there is evidence of a positive association between the survival and the longitudinal sub-models. Thus, defaulting is more likely to occur in patients with higher pulse rates. Patients, being male, hypertensive, CKD, pneumonic, and NYHA class IV patients were associated with a higher risk of defaulting. Age, LVIF, follow-up time in a month had a negative significant effect and NYHA class, and male gender had a positive significant effect on average evaluation of pulse rate of patients. Conclusions: The patient who are male, NYHA class IV, had low LVIF and comorbid with hypertensive, CKD, pneumonia were risk factors of pulse rate change and defaulting from treatment of CHF patients. The joint model was preferred for simultaneous analyses of repeated measurement and survival data.


2008 ◽  
Vol 14 (7) ◽  
pp. S140-S141
Author(s):  
Kenji Ando ◽  
Yoshimitsu Soga ◽  
Masahiko Goya ◽  
Shinichi Shirai ◽  
Shinya Nagayama ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
H.Y Chang ◽  
W.R Chiou ◽  
P.L Lin ◽  
C.Y Hsu ◽  
C.T Liao ◽  
...  

Abstract Background Ischemic cardiomyopathy (ICM) has been associated with increased mortality when compared with non-ischemic cardiomyopathy (NICM) from several heart failure (HF) cohorts. Instead, PARADIGM study demonstrated similar event rates of cardiovascular (CV) death, all-cause mortality and HF readmissions between ICM and NICM patients. Although the beneficiary effect of sacubitril/valsartan (SAC/VAL) compared to enalapril on these endpoints was consistent across etiologic categories, PARADIGM study did not analyze the effect of ventricular remodeling of SAC/VAL on patients with different HF etiologies, which may significantly affect treatment outcomes. Purpose We aim to compare alterations of left ventricular ejection fraction (LVEF) following SAC/VAL treatment and its association with clinical outcomes in patients with different HF etiologies. Methods Treatment with angiotensin receptor neprilysin inhibitor for Taiwan heart failure patients (TAROT-HF) study is a multicenter study which enrolled 1552 patients with LVEF <40%, whom had been on SAC/VAL treatment from 9 hospitals between 2017 and 2018. After excluding patients without having follow-up echocardiographic studies, patients were grouped by HF etiologies and by LVEF changes following treatment for 8-month period. LVEF improvement ≥15% was defined as “significant improvement”, 5–15% as “marginal improvement”, and <5% or worse as “lack of improvement”. The primary endpoint was a composite of CV death or a first hospitalization for HF. Mean follow-up period was 726 days. Results A total of 1230 patients were analyzed. Patients with ICM were significantly older, more male, and prone to have associated hypertension and diabetes. On the other hand, patients with NICM had lower LVEF and higher likelihood of atrial fibrillation. LVEF increase was significantly greater in patients with NICM compared to those with ICM (11.2±12.4% vs. 6.9±9.8, p<0.001). The effect of ventricular remodeling of SAC/VAL on patients with NICM showed twin peaks diversity (Significant improvement 37.1%, lack of improvement 42.3%), whereas in patients with ICM the proportions of significant, marginal and lack of improvement groups were 19.4%, 28.2% and 52.4%, respectively. The primary endpoint showed twin peaks diversity also in patients with NICM in line with LVEF changes: adjusted HR for patients with NICM and significant improvement was 0.41 (95% CI 0.29–0.57, p<0.001), for patients with NICM and lack of improvement was 1.54 (95% CI 1.22–1.94, p<0.001). Analyses for CV death, all-cause mortality, and HF readmission demonstrated consistent results. Conclusion Patients with NICM had higher degree of LVEF improvement than those with ICM following SAC/VAL treatment, and significant improvement of LVEF in NICM patients may indicate favorable outcome. NICM patients without response to SAC/VAL treatment should serve as an indicator for poor clinical outcome and warranted meticulous HF management. Funding Acknowledgement Type of funding source: Private hospital(s). Main funding source(s): Cheng Hsin General Hospital


1998 ◽  
Vol 26 (8) ◽  
pp. 57-57
Author(s):  
James R. Clark ◽  
Carl Sherman ◽  
Nicholas A. DiNubile

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