Prevention of Deep Vein Thrombosis and Pulmonary Embolism in High-Risk Medical Patients

2018 ◽  
Vol 39 (3) ◽  
pp. 483-492 ◽  
Author(s):  
Megan McCullough ◽  
Cyrus Kholdani ◽  
Roham T. Zamanian
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
High Risk ◽  
Medical Patients ◽  
Vein Thrombosis ◽  
Deep Vein

The Relationship between 125I-Fibrinogen Detected Thrombosis and Pulmonary Embolism

1975 ◽  
Author(s):  
G. V. Ruckley ◽  
D. R. B. Jones ◽  
I. M. C. Macintyre ◽  
C. Vasilescu
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Cause Of Death ◽  
Screening Test ◽  
Medical Patients ◽  
Vein Thrombosis ◽  
Lung Scan ◽  
Fibrinogen Test ◽  
Deep Vein ◽  
The Relationship

A total of 846 surgical and medical patients have been screened by the 125I-fibrinogen test (I.F.T.). Deep vein thrombosis (D.V.T.) was detected in 174 (21%). In 49% of positives the condition was bilateral and in 33% the D.V.T. involved popliteal veins or above. In 14 patients pulmonary embolism was diagnosed by lung scan or at autopsy. In one massive embolism was the cause of death. All 14 had positive I.F.T’s. ; 10 bilateral and 10 with both calf and thigh vein thrombus. The relationship between positive I.F.T. and iliofemoral D.V.T. was studied with bilateral phlebography in 60 patients. In no case was isolated iliofemoral D.V.T found. We confirm the value of the I.F.T. as a screening test for potential embolism and observe that embolism from isolated iliofemoral D.V.T. is extremely rare.

scholarly journals Real-World Rates of In-hospital and Postdischarge Deep-Vein Thrombosis and Pulmonary Embolism in At-Risk Medical Patients in the United States

2011 ◽  
Vol 17 (6) ◽  
pp. 611-619 ◽  
Author(s):  
Alpesh N. Amin ◽  
Jay Lin ◽  
Stephen Thompson ◽  
Daniel Wiederkehr
Keyword(s):  
Infectious Disease ◽  
At Risk ◽  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
The United States ◽  
Outpatient Setting ◽  
Medical Patients ◽  
Vein Thrombosis ◽  
Patients With Cancer ◽  
Deep Vein

Hospitalized medical patients are at risk of deep-vein thrombosis (DVT) and pulmonary embolism (PE). We evaluated inpatient and postdischarge DVT/PE and thromboprophylaxis rates in US medical patients, using patient admissions from January 2005 to November 2007 in the Premier Perspective™-i3 Pharma Informatics database. Among 15 721 patients with cancer, congestive heart failure, severe lung disease, and infectious disease, 39.0% received inpatient thromboprophylaxis, with the highest rate in patients with cancer (51.9%). In all, 3.4% received outpatient pharmacological prophylaxis. Mean ± SD prophylaxis duration was 2.2 ± 5.7 days. Overall, 3.0% of inpatients had symptomatic DVT/PE, and an additional 1.1% of patients were rehospitalized for DVT/PE or treated in the outpatient setting. Patients with infectious disease had the highest rate of DVT/PE (4.6%). Inpatient DVT/PE and prophylaxis rates of the different medical conditions had a negative correlation ( R 2 = 0.72). This analysis demonstrates the burden of DVT/PE and highlights the underuse of thromboprophylaxis across the continuum of care.

Surveillance and Early Management of Deep Vein Thrombosis Decreases the Rate of Pulmonary Embolism in High-Risk Trauma Patients

2015 ◽  
Vol 221 (4) ◽  
pp. S167
Author(s):  
Casey J. Allen ◽  
Jonathan P. Meizoso ◽  
Joyce Kaufman ◽  
Laura F. Teisch ◽  
Xiomara D. Ruiz ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
High Risk ◽  
Trauma Patients ◽  
Early Management ◽  
Vein Thrombosis ◽  
Deep Vein

Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism

Blood ◽  
2014 ◽  
Vol 123 (12) ◽  
pp. 1794-1801 ◽  
Author(s):  
Clive Kearon ◽  
Elie A. Akl
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
High Risk ◽  
Anticoagulant Therapy ◽  
Low Risk ◽  
Risk Of Recurrence ◽  
Vein Thrombosis ◽  
Risk Of Bleeding ◽  
Deep Vein

Abstract It takes about 3 months to complete “active treatment” of venous thromboembolism (VTE), with further treatment serving to prevent new episodes of thrombosis (“pure secondary prevention”). Consequently, VTE should generally be treated for either 3 months or indefinitely (exceptions will be described in the text). The decision to stop anticoagulants at 3 months or to treat indefinitely is dominated by the long-term risk of recurrence, and secondarily influenced by the risk of bleeding and by patient preference. VTE provoked by a reversible risk factor, or a first unprovoked isolated distal (calf) deep vein thrombosis (DVT), has a low risk of recurrence and is usually treated for 3 months. VTE associated with active cancer, or a second unprovoked VTE, has a high risk of recurrence and is usually treated indefinitely. The decision to stop anticoagulants at 3 months or to treat indefinitely is more finely balanced after a first unprovoked proximal DVT or pulmonary embolism (PE). Indefinite anticoagulation is often chosen if there is a low risk of bleeding, whereas anticoagulation is usually stopped at 3 months if there is a high risk of bleeding. The decision to continue anticoagulation indefinitely after a first unprovoked proximal DVT or PE is strengthened if the patient is male, the index event was PE rather than DVT, and/or d-dimer testing is positive 1 month after stopping anticoagulant therapy.

Surveillance and Early Management of Deep Vein Thrombosis Decreases Rate of Pulmonary Embolism in High-Risk Trauma Patients

2016 ◽  
Vol 222 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Casey J. Allen ◽  
Clark R. Murray ◽  
Jonathan P. Meizoso ◽  
Enrique Ginzburg ◽  
Carl I. Schulman ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
High Risk ◽  
Trauma Patients ◽  
Early Management ◽  
Vein Thrombosis ◽  
Deep Vein

Is Colour Doppler Ultrasound a Sensitive Screening Method in Diagnosing Deep Vein Thrombosis after Hip Surgery ?

1996 ◽  
Vol 75 (02) ◽  
pp. 242-245 ◽  
Author(s):  
Marie Magnusson ◽  
Bengt I Eriksson ◽  
Peter Kãlebo ◽  
Ramon Sivertsson
Keyword(s):  
Deep Vein Thrombosis ◽  
High Risk ◽  
Doppler Ultrasound ◽  
Predictive Value ◽  
Screening Method ◽  
Colour Doppler ◽  
Vein Thrombosis ◽  
Colour Doppler Ultrasound ◽  
Asymptomatic Patients ◽  
Deep Vein

SummaryPatients undergoing orthopedic surgery are at high risk of developing deep vein thrombosis. One hundred and thirty-eight consecutive patients undergoing total hip replacement or hip fracture surgery were included in this study. They were surveilled with colour Doppler ultrasound (CDU) and bilateral ascending contrast phlebography. The prevalence of proximal and distal DVT in this study was 5.8% and 20.3% respectively.CDU has a satisfactory sensitivity in patients with symptomatic deep vein thrombosis, especially in the proximal region. These results could not be confirmed in the present study of asymptomatic patients. The sensitivity was 62.5% (95% confidence interval: C.I. 24-91%) and the specificity 99.6% (C.I. 98-100%) for proximal DVT; 53.6% (C.I. 34-73%) and 98% (C.I. 96-99%) respectively for distal thrombi. The overall sensitivity was 58.1% (C.I. 39-75%) and the specificity 98% (C.I. 96-99%). The positive predictive value was 83.3% (C.I. 36-99%) and 75% (C.I. 51-91%) for proximal and distal DVT respectively. The negative predictive value was 98.9% (C.I. 98-100%) and 94.9% (C.I. 92-98%) for proximal and distal DVT respectively. The results of this study showed that even with a highly specialised and experienced investigator the sensitivity of CDU was too low to make it suitable for screening purposes in a high risk surgical population.

Sign in / Sign up

Export Citation Format

Share Document