Interaction between mannosylated lipoarabinomannan and dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin influences dendritic cells maturation and T cell immunity

2011 ◽  
Vol 272 (1) ◽  
pp. 94-101 ◽  
Author(s):  
Tingting Wu ◽  
Shuliang Guo ◽  
Jianjun Wang ◽  
Lan Li ◽  
Lulu Xu ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Dendritic Cell ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
T Cell Immunity ◽  
Intercellular Adhesion Molecule ◽  
Cell Immunity

scholarly journals Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin Mediates Binding and Internalization ofAspergillus fumigatusConidia by Dendritic Cells and Macrophages

2004 ◽  
Vol 173 (9) ◽  
pp. 5635-5643 ◽  
Author(s):  
Diego Serrano-Gómez ◽  
Angeles Domínguez-Soto ◽  
Julio Ancochea ◽  
José A. Jimenez-Heffernan ◽  
Juan Antonio Leal ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dendritic Cell ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Intercellular Adhesion Molecule

scholarly journals Cocaine Modulates Dendritic Cell-Specific C Type Intercellular Adhesion Molecule-3-Grabbing Nonintegrin Expression by Dendritic Cells in HIV-1 Patients

2005 ◽  
Vol 174 (11) ◽  
pp. 6617-6626 ◽  
Author(s):  
Madhavan P. N. Nair ◽  
Supriya D. Mahajan ◽  
Stanley A. Schwartz ◽  
Jessica Reynolds ◽  
Robert Whitney ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dendritic Cell ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Intercellular Adhesion Molecule ◽  
Hiv 1

scholarly journals Optimal CD8 T-Cell Response against Encephalitozoon cuniculi Is Mediated by Toll-Like Receptor 4 Upregulation by Dendritic Cells

2010 ◽  
Vol 78 (7) ◽  
pp. 3097-3102 ◽  
Author(s):  
Elizabeth M. Lawlor ◽  
Magali M. Moretto ◽  
Imtiaz A. Khan
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Dendritic Cell ◽  
Cell Response ◽  
T Cell Response ◽  
T Cell Immunity ◽  
Toll Like Receptor ◽  
Encephalitozoon Cuniculi ◽  
Toll Like Receptor 4 ◽  
Cell Immunity

ABSTRACT CD8+ T-cell immunity has been shown to play an important role in the protective immune response against Encephalitozoon cuniculi. Although earlier studies suggest that dendritic cells (DC) are important for the induction of this response, the factors responsible for initiation of the dendritic cell response against this pathogen have not been evaluated. In the current study, we demonstrate that E. cuniculi infection causes strong Toll-like receptor 4 (TLR4)-dependent dendritic cell activation and a blockade of this molecule reduces the ability of DC to prime an antigen-specific CD8+ T-cell response. Pretreatment of DC with anti-TLR4 antibody causes a defect in both in vitro and in vivo CD8+ T-cell priming. These findings, for the first time, emphasize the contribution of TLR4 in the induction of CD8+ T-cell immunity against E. cuniculi infection.

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