Long-term bisphenol S exposure induces fat accumulation in liver of adult male zebrafish (Danio rerio) and slows yolk lipid consumption in F1 offspring

Chemosphere ◽  
2019 ◽  
Vol 221 ◽  
pp. 500-510 ◽  
Author(s):  
Weiwei Wang ◽  
Xiaona Zhang ◽  
Jingyu Qin ◽  
Penghao Wei ◽  
Yi Jia ◽  
...  
Keyword(s):  
Adult Male ◽  
Danio Rerio ◽  
Bisphenol S ◽  
Fat Accumulation ◽  
Yolk Lipid

Long-term exposure to bisphenol S damages the visual system and reduces the tracking capability of male zebrafish (Danio rerio)

2017 ◽  
Vol 38 (2) ◽  
pp. 248-258 ◽  
Author(s):  
Wenmin Liu ◽  
Xiaona Zhang ◽  
Penghao Wei ◽  
Hua Tian ◽  
Wei Wang ◽  
...  
Keyword(s):  
Visual System ◽  
Danio Rerio ◽  
Bisphenol S

scholarly journals Persistent Exposure to Environmental Levels of Microcystin-LR Disturbs Cortisol Production via Hypothalamic-Pituitary-Interrenal (HPI) Axis and Subsequently Liver Glucose Metabolism in Adult Male Zebrafish (Danio rerio)

Toxins ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 282 ◽  
Author(s):  
Lingkai Wang ◽  
Wang Lin ◽  
Qingji Zha ◽  
Honghui Guo ◽  
Dandan Zhang ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Adult Male ◽  
Danio Rerio ◽  
Serum Cortisol ◽  
Serum Glucose ◽  
Related Gene ◽  
Impaired Glucose Metabolism ◽  
Hpi Axis ◽  
Lower Production

There is growing evidence that microcystin-LR (MC-LR) is a new endocrine disruptor, whereas the impacts of persistent exposure to MC-LR on the hypothalamic-pituitary-interrenal (HPI) axis and health hazards thereafter have not been investigated. In this work, adult male zebrafish (Danio rerio) were immersed into MC-LR solutions at concentrations of 0, 1, 5 and 25 μg/L for 30 d, respectively. The results showed that persistent MC-LR exposure caused an extensive upregulation of HPI-axis genes but an inhibition of brain nuclear receptors (gr and mr), which finally increased serum cortisol levels. Furthermore, the decreased expression of hepatic gr might partly be responsible for the strong inhibition on the expression of downstream genes involved in glucose metabolic enzymes, including gluconeogenesis-related genes (pepck, fbp1a, g6pca), glycogenolysis-related gene (pyg), glycolysis-related genes (gk, pfk1b, pk) and glycogenesis-related gene (gys2). These findings are in accordance with the decline in serum glucose, indicating that long-term MC-LR exposure caused a lower production of glucose relative to glucose lysis. Our above results firstly establish the link between persistent MC-LR exposure and impaired glucose metabolism, suggesting that long-term MC-LR-mediated stress might threaten fish’s health.

Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio)

2012 ◽  
Vol 120-121 ◽  
pp. 11-18 ◽  
Author(s):  
Lianguo Chen ◽  
Chenyan Hu ◽  
Changjiang Huang ◽  
Qiangwei Wang ◽  
Xiaofang Wang ◽  
...  
Keyword(s):  
Danio Rerio

Sex specific response in cholesterol level in zebrafish ( Danio rerio ) after long-term exposure of difenoconazole

2015 ◽  
Vol 197 ◽  
pp. 278-286 ◽  
Author(s):  
Xiyan Mu ◽  
Kai Wang ◽  
Tingting Chai ◽  
Lizhen Zhu ◽  
Yang Yang ◽  
...  
Keyword(s):  
Cholesterol Level ◽  
Danio Rerio ◽  
Specific Response

Neurobehavioral effects of bisphenol S exposure in early life stages of zebrafish larvae (Danio rerio)

Chemosphere ◽  
2019 ◽  
Vol 217 ◽  
pp. 629-635 ◽  
Author(s):  
Jie Gu ◽  
Jiayao Zhang ◽  
Yaoyao Chen ◽  
Hongye Wang ◽  
Min Guo ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Early Life ◽  
Life Stages ◽  
Early Life Stages ◽  
Bisphenol S ◽  
Zebrafish Larvae ◽  
Neurobehavioral Effects
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