CARDIAC TAMPONADE: BEYOND PERICARDIAL EFFUSION: A TALE OF TWO COMPRESSIVE MEDIASTINAL MASSES

Anterior mediastinal masses are relatively uncommon and include a wide variety of lesions. Lymphomas account for 25% of anterior mediastinal masses. Lymphomas and other haematological malignancies are associated with pericardial effusion. There are also cases where a cardiac tamponade occurred. The aim of the case reported herein is to discuss the surgical approach and particularly the mediastinal debulking as an adjunct to systematic treatment for haematological diseases presenting as an anterior mediastinal mass responsible for a cardiac tamponade.

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Malignant pericardial effusion complicated by cardiac tamponade under atezolizumab

SAGE Open Medical Case Reports ◽

10.1177/2050313x211036005 ◽

2021 ◽

Vol 9 ◽

pp. 2050313X2110360

Author(s):

Lardinois Benjamin ◽

Goeminne Jean-Charles ◽

Miller Laurence ◽

Randazzo Adrien ◽

Laurent Terry ◽

...

Keyword(s):

Pericardial Effusion ◽

Cardiac Tamponade ◽

Cardiac Toxicity ◽

Checkpoint Inhibitors ◽

Final Diagnosis ◽

Pericardial Fluid ◽

Malignant Pericardial Effusion ◽

Typical Cell ◽

High Fluorescence ◽

Tomography Scan

Immune-related adverse events including cardiac toxicity are increasingly described in patients receiving immune checkpoint inhibitors. We described a malignant pericardial effusion complicated by a cardiac tamponade in an advanced non-small cell lung cancer patient who had received five infusions of atezolizumab, a PDL-1 monoclonal antibody, in combination with cabozantinib. The definitive diagnosis was quickly made by cytology examination showing typical cell abnormalities and high fluorescence cell information provided by the hematology analyzer. The administration of atezolizumab and cabozantinib was temporarily discontinued due to cardiogenic hepatic failure following cardiac tamponade. After the re-initiation of the treatment, pericardial effusion relapsed. In this patient, the analysis of the pericardial fluid led to the final diagnosis of pericardial tumor progression. This was afterwards confirmed by the finding of proliferating intrapericardial tissue by computed tomography scan and ultrasound. This report emphasizes the value of cytology analysis performed in a hematology laboratory as an accurate and immediate tool for malignancy detection in pericardial effusions.

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CHYLOUS PERICARDIAL EFFUSION CAUSING CARDIAC TAMPONADE: A RARE MANIFESTATION OF SUPERIOR VENA CAVA OBSTRUCTION

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(21)03988-7 ◽

2021 ◽

Vol 77 (18) ◽

pp. 2633

Author(s):

Arindam Sharma ◽

Abhishek Thandra ◽

Eric Van De Graaff

Keyword(s):

Pericardial Effusion ◽

Cardiac Tamponade ◽

Superior Vena Cava ◽

Superior Vena ◽

Vena Cava ◽

Superior Vena Cava Obstruction ◽

Rare Manifestation

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Pericardial effusion and cardiac tamponade requiring pericardial window in an otherwise healthy 30-year-old patient with COVID-19: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-020-02467-w ◽

2020 ◽

Vol 14 (1) ◽

Author(s):

Christina Walker ◽

Vincent Peyko ◽

Charles Farrell ◽

Jeanine Awad-Spirtos ◽

Matthew Adamo ◽

...

Keyword(s):

Case Report ◽

Pericardial Effusion ◽

Cardiac Tamponade ◽

Case Reports ◽

Healthy Woman ◽

Signs And Symptoms ◽

Rare Presentation ◽

Pericardial Window ◽

Acute Pericarditis ◽

Novel Coronavirus

Abstract Background This case report demonstrates pericardial effusion, acute pericarditis, and cardiac tamponade in an otherwise healthy woman who had a positive test result for coronavirus disease 2019. Few case reports have been documented on patients with this presentation, and it is important to share novel presentations of the disease as they are discovered. Case presentation A Caucasian patient with coronavirus disease 2019 returned to the emergency department of our hospital 2 days after her initial visit with worsening chest pain and shortness of breath. Imaging revealed new pericardial effusion since the previous visit. The patient became hypotensive, was taken for pericardial window for cardiac tamponade with a drain placed, and was treated for acute pericarditis. Conclusion Much is still unknown about the implications of coronavirus disease 2019. With the novel coronavirus disease 2019 pandemic, research is still in process, and we are slowly learning about new signs and symptoms of the disease. This case report documents a lesser-known presentation of a patient with coronavirus disease 2019 and will help to further understanding of a rare presentation.

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Pericardial effusion and cardiac tamponade: clinical manifestation of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Revista Brasileira de Hematologia e Hemoterapia ◽

10.5581/1516-8484.20140034 ◽

2014 ◽

Vol 36 (2) ◽

pp. 159-161 ◽

Cited By ~ 6

Author(s):

David Cavalcanti Ferreira ◽

José Salvador Rodrigues de Oliveira ◽

Katya Parísio ◽

Fernanda Maria Morselli Ramalho

Keyword(s):

Stem Cell ◽

Pericardial Effusion ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cardiac Tamponade ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Graft Versus Host Disease ◽

Hematopoietic Stem ◽

Graft Versus Host

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Cardiac tamponade caused by primary lung cancer and the management of pericardial effusion

Lung Cancer ◽

10.1016/0169-5002(93)90232-m ◽

1993 ◽

Vol 10 (3-4) ◽

pp. 273-274

Keyword(s):

Lung Cancer ◽

Pericardial Effusion ◽

Cardiac Tamponade ◽

Primary Lung Cancer

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Incidence and Outcomes of Pericardial Effusion and Cardiac Tamponade Following Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation

The American Journal of Cardiology ◽

10.1016/j.amjcard.2021.07.027 ◽

2021 ◽

Author(s):

Agam Bansal ◽

Ankur Kalra ◽

Rishi Puri ◽

Walid Saliba ◽

Amar Krishnaswamy ◽

...

Keyword(s):

Pericardial Effusion ◽

Aortic Valve ◽

Cardiac Tamponade ◽

Transcatheter Aortic Valve Implantation ◽

Pacemaker Implantation ◽

Permanent Pacemaker ◽

Permanent Pacemaker Implantation ◽

Transcatheter Aortic Valve ◽

Aortic Valve Implantation ◽

Valve Implantation

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Cardiac tamponade as an unusual initial presentation of squamous cell carcinoma of the esophagus

10.22514/sv.2021.120 ◽

2021 ◽

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Cancer ◽

Pericardial Effusion ◽

Cell Carcinoma ◽

Cardiac Tamponade ◽

Squamous Cell ◽

Unknown Etiology ◽

Thoracic Esophagus ◽

Moderate Amount ◽

Carcinoma Of The Esophagus

Pericardial effusions leading to cardiac tamponade have previously been described with esophageal cancer. However, up to eighty percent of these cases have been reported in association with chemotherapy and radiation. Patients with esophageal cancer seldom initially present with pericardial effusion resulting from esophageal pericardial fistula (EPF). Herein, we present the case of a 62-year-old man who presented with pericardial effusion with an unknown etiology at presentation. Subsequently, the patient developed cardiac tamponade and was referred to the tertiary hospital for further evaluation. Computed tomography of the chest revealed a circumferential irregular enhancing lesion at the mid-thoracic esophagus suspecting esophageal cancer with EPF and a moderate amount of pericardial effusion. The patient underwent esophagoscopy and squamous cell carcinoma was found from the esophageal biopsy. An esophageal stent was successfully placed to conceal the perforation. Eventually, the patient died 13 days after admission complicated by refractory septic shock. This case highlights an atypical presentation of esophageal cancer and an unusual cause of cardiac tamponade.

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