High-performance liquid chromatography with contactless conductivity detection for the determination of peptides and proteins using a monolithic capillary column

2007 ◽  
Vol 1176 (1-2) ◽  
pp. 185-191 ◽  
Author(s):  
Pavel Kubáň ◽  
Peter C. Hauser
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Capillary Column ◽  
Conductivity Detection ◽  
Contactless Conductivity Detection ◽  
Monolithic Capillary Column

Determination of trace fungicides in environmental water samples using poly(HPMA-EDMA) monolith microextraction coupled to high performance liquid chromatography

2014 ◽  
Vol 6 (13) ◽  
pp. 4783-4789 ◽  
Author(s):  
Mi Chen ◽  
Miao Zhang ◽  
Xiangfang Wang ◽  
Sha Peng ◽  
Jing Cheng
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Capillary Column ◽  
Environmental Water ◽  
Polymer Monolith ◽  
Polymer Monolith Microextraction ◽  
Ethylene Dimethacrylate ◽  
Monolithic Capillary Column

A novel poly(2-hydroxypropyl methacrylate-ethylene dimethacrylate) (HPMA-EDMA) monolithic capillary column was synthesized and selected as the extraction medium for polymer monolith microextraction (PMME).

scholarly journals Analysis of Quinapril by Two Solvent-Saving Methods: Application of Capillary Column High-Performance Liquid Chromatography with Ultraviolet Absorbance Detection and LDI-TOF-MS

2010 ◽  
Vol 93 (4) ◽  
pp. 1201-1206
Author(s):  
Chi-Yu Lu ◽  
Yi-Rou Wang ◽  
Su-Hwei Chen ◽  
Chia-Hsien Feng
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Capillary Column ◽  
Enzyme Inhibitor ◽  
Internal Standard ◽  
Ionization Time ◽  
Absorbance Detection ◽  
Tof Ms

Abstract A capillary column high-performance liquid chromatography (CapLC) method and a laser desorption ionization-time of flight (LDI-TOF)-MS method are described for the determination of quinapril, an angiotensin-converting enzyme inhibitor. Effective separation was achieved by using a C18 capillary column at a flow rate of 10 L/min. For CapLC, quinapril and 7-hydroxycoumarin (internal standard) were detected at 210 and 320 nm, respectively. Phenformin replaced 7-hydroxycoumarin as the internal standard for the LDI-TOF-MS method successfully developed to detect quinapril. The calibration curves showed good linearity in the range of 1100 g/mL in these two methods. For high throughput purposes, the LDI-TOF-MS method was simpler and faster than the CapLC method. Both green methods were suitably validated and successfully applied to determine quinapril in commercial tablets.

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