Capillary size exclusion chromatography with picogram sensitivity for analysis of monoclonal antibodies purified from harvested cell culture fluid

Culture Fluid ◽

Size Exclusion ◽

Cell Culture Fluid ◽

Capillary Size

Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

mAbs ◽

10.1080/19420862.2019.1702263 ◽

2019 ◽

Vol 12 (1) ◽

pp. 1702263 ◽

Cited By ~ 3

Author(s):

Zachary D. Dunn ◽

Jayesh Desai ◽

Gabriel M. Leme ◽

Dwight R. Stoll ◽

Douglas D. Richardson

Keyword(s):

Cell Culture ◽

Monoclonal Antibodies ◽

Protein A ◽

Culture Fluid ◽

Size Exclusion ◽

Two Dimensional ◽

Cell Culture Fluid

Development of capillary size exclusion chromatography for the analysis of monoclonal antibody fragments extracted from human vitreous humor

Journal of Chromatography A ◽

10.1016/j.chroma.2012.10.051 ◽

2012 ◽

Vol 1270 ◽

pp. 111-117 ◽

Cited By ~ 7

Author(s):

Jennifer C. Rea ◽

Yun Lou ◽

Joel Cuzzi ◽

Yuhua Hu ◽

Isabella de Jong ◽

...

Keyword(s):

Monoclonal Antibody ◽

Vitreous Humor ◽

Antibody Fragments ◽

Size Exclusion ◽

Capillary Size

Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography

Journal of Biotechnology ◽

10.1016/j.jbiotec.2015.02.026 ◽

2015 ◽

Vol 213 ◽

pp. 54-64 ◽

Cited By ~ 31

Author(s):

Amit K. Dutta ◽

Travis Tran ◽

Boris Napadensky ◽

Achyuta Teella ◽

Gary Brookhart ◽

...

Keyword(s):

Cell Culture ◽

Monoclonal Antibodies ◽

Protein A ◽

Culture Fluid ◽

Cell Culture Fluid ◽

Continuous Countercurrent

Application of phase partitioning and thiophilic adsorption chromatography to the purification of monoclonal antibodies from cell culture fluid

Journal of Immunological Methods ◽

10.1016/0022-1759(92)90247-q ◽

1992 ◽

Vol 149 (2) ◽

pp. 165-171 ◽

Cited By ~ 24

Author(s):

Barbara Sulk ◽

Gerd Birkenmeier ◽

Gerhard Kopperschläger

Keyword(s):

Cell Culture ◽

Monoclonal Antibodies ◽

Culture Fluid ◽

Adsorption Chromatography ◽

Phase Partitioning ◽

Cell Culture Fluid

Fiber-based HIC capture loop for coupling of protein A and size exclusion chromatography in a two-dimensional separation of monoclonal antibodies

Analytica Chimica Acta ◽

10.1016/j.aca.2019.11.023 ◽

2020 ◽

Vol 1098 ◽

pp. 190-200 ◽

Cited By ~ 1

Author(s):

Lei Wang ◽

Hung K. Trang ◽

Jay Desai ◽

Zachary D. Dunn ◽

Douglas D. Richardson ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Protein A ◽

Size Exclusion ◽

Two Dimensional ◽

Post-Column Denaturation-Assisted Native Size-Exclusion Chromatography–Mass Spectrometry for Rapid and In-Depth Characterization of High Molecular Weight Variants in Therapeutic Monoclonal Antibodies

Journal of the American Society for Mass Spectrometry ◽

10.1021/jasms.1c00289 ◽

2021 ◽

Author(s):

Yuetian Yan ◽

Tao Xing ◽

Anita P. Liu ◽

Zhengqi Zhang ◽

Shunhai Wang ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Monoclonal Antibodies ◽

High Molecular Weight ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Therapeutic Monoclonal Antibodies

Importance of vial shape and type on the reproducibility of size exclusion chromatography measurement of monoclonal antibodies

Journal of Chromatography B ◽

10.1016/j.jchromb.2016.04.032 ◽

2016 ◽

Vol 1032 ◽

pp. 131-138 ◽

Cited By ~ 6

Author(s):

Marta Rodriguez-Aller ◽

Alessandra Cusumano ◽

Beck Alain ◽

Davy Guillarme ◽

Szabolcs Fekete

Keyword(s):

Monoclonal Antibodies ◽

Size Exclusion ◽

Nondenaturing Size-Exclusion Chromatography-Mass Spectrometry to Measure Stress-Induced Aggregation in a Complex Mixture of Monoclonal Antibodies

Analytical Chemistry ◽

10.1021/ac401455f ◽

2013 ◽

Vol 85 (13) ◽

pp. 6429-6436 ◽

Cited By ~ 23

Author(s):

Jonathan Woodard ◽

Hollis Lau ◽

Ramil F. Latypov

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Complex Mixture ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Induced Aggregation

Analysis of reduced monoclonal antibodies using size exclusion chromatography coupled with mass spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2009.08.015 ◽

2009 ◽

Vol 20 (12) ◽

pp. 2258-2264 ◽

Cited By ~ 40

Author(s):

Hongcheng Liu ◽

Georgeen Gaza-Bulseco ◽

Chris Chumsae

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Size Exclusion ◽

Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies

Scientific Reports ◽

10.1038/s41598-017-15717-7 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 59

Author(s):

Birke J. Benedikter ◽

Freek G. Bouwman ◽

Tanja Vajen ◽

Alexandra C. A. Heinzmann ◽

Gert Grauls ◽

...

Keyword(s):

Cell Culture ◽

Extracellular Vesicles ◽

Culture Media ◽

Size Exclusion ◽

Cell Culture Media ◽

Functional Studies ◽