Distinct Expression of Nonmuscle Myosin IIB in Pulmonary Arteries of Patients With Aortic Stenosis vs Insufficiency Undergoing a Ross Procedure

2021 ◽  
Vol 37 (1) ◽  
pp. 47-56
Author(s):  
Alexander Emmott ◽  
Vanessa Hertig ◽  
Alexandre Bergeron ◽  
Louis Villeneuve ◽  
Laurence Lefebvre ◽  
...  

2012 ◽  
Vol 15 (4) ◽  
pp. 182
Author(s):  
Fotios A. Mitropoulos ◽  
Meletios A. Kanakis ◽  
Sotiria C. Apostolopoulou ◽  
Spyridon Rammos ◽  
Constantine E. Anagnostopoulos

<p>Mechanical and biological prostheses are valid options when aortic valve replacement is necessary. The Ross procedure is also an alternative solution, especially for young patients.</p><p>We describe the case of a young patient with congenital aortic stenosis and bicuspid aortic valve who presented with dyspnea on exertion. An open commissurotomy was performed, and within 8 months the patient developed recurrent symptoms of severe aortic stenosis. He underwent redo sternotomy and a Ross-Konno procedure with an uneventful recovery.</p>



2019 ◽  
Vol 10 (5) ◽  
pp. 624-627
Author(s):  
Jeremy L. Herrmann ◽  
Amanda R. Stram ◽  
John W. Brown

Prosthesis choice for aortic valve replacement (AVR) in children is frequently compromised by unavailability of prostheses in very small sizes, the lack of prosthetic valve growth, and risks associated with long-term anticoagulation. The Ross procedure with pulmonary valve autograft offers several advantages for pediatric and adult patients. We describe our current Ross AVR technique including replacement of the ascending aorta with a prosthetic graft. The procedure shown in the video involves an adult-sized male with a bicuspid aortic valve, mixed aortic stenosis and insufficiency, and a dilated ascending aorta.



2014 ◽  
Vol 47 (1) ◽  
pp. 159-167 ◽  
Author(s):  
David Kalfa ◽  
Siamak Mohammadi ◽  
Dimitri Kalavrouziotis ◽  
Mounir Kharroubi ◽  
Daniel Doyle ◽  
...  


2015 ◽  
Vol 17 (1) ◽  
pp. 5
Author(s):  
A. M. Karaskov ◽  
I. I. Demin ◽  
S. I. Zheleznev ◽  
A. V. Bogachev-prokofev ◽  
R. M. Sharifulin ◽  
...  

The Ross procedure outcomes in patients with left ventricular dysfunction are presented. 20 Ross procedures were performed in patients with aortic disease complicated by severe left ventricular dysfunction. The average left ventricular ejection fraction before surgery was 31,56,57%. Aortic stenosis was found in 60% of cases. Hospital mortality rate was 5%. Heart failure prevailed among complications. It was already in the early postoperative period that significant left ventricular remodeling was observed. The patients with aortic stenosis demonstrated a 56,9 % increase in ejection fraction, while their end-systolic diameter and end-systolic volume decreased by 34,5% and 13,3% respectively. In the group with aortic insufficiency there was a statistically significant reduction in the left ventricular volume indices: left ventricular end-diastolic diameter by 20%, left ventricular end-diastolic volume by 36,5%. No reoperation due to dysfunction of the autograft and conduits in the pulmonary artery area was required. At 12 months after surgery the processes of left ventricular cavity remodeling and normalization of contractility in both groups continued. The results of this study show that the Ross procedure can be used successfully in patients with severe left ventricular systolic dysfunction.



2019 ◽  
Vol 11 (1) ◽  
pp. 127-129
Author(s):  
Ari Cedars ◽  
Kamlesh Jobanputra ◽  
David Bichell

We present a unique surgical complication in a 19-year-old patient who underwent a “supported” Ross procedure for congenital aortic stenosis. In the present case, herniation of pulmonary autograft material through coronary fenestrations in the Dacron supporting material can be appreciated. This case suggests a possible need to modify surgical technique to ensure that all autograft tissue remains contained within the Dacron bolster.



2013 ◽  
Vol 17 (suppl 2) ◽  
pp. S135-S136
Author(s):  
S. Mohammadi ◽  
D. Kalfa ◽  
D. Kalavrouziotis ◽  
M. Kharroubi ◽  
D. Doyle ◽  
...  


Author(s):  
Sok-Leng Kang ◽  
Robin Martin

The clinical management of severe aortic stenosis in the newborn period is complex and challenging. This chapter presents case of severe aortic stenosis in a 3-day-old neonate who required multiple interventions in infancy, including balloon aortic valvuloplasty, the Ross procedure, pulmonary conduit replacement, and branch pulmonary artery stenting. The chapter outlines the clinical signs and symptoms of aortic stenosis in neonates, detailed echocardiographic and haemodynamic assessment of the morphology and severity of the lesion, and indications for intervention. Treatment options and the evidence surrounding each are also explored. Ultimately, the optimal treatment strategy and timing of intervention are likely to depend on local expertise and clinical condition at presentation.



2013 ◽  
Vol 145 (6) ◽  
pp. 1504-1511 ◽  
Author(s):  
Robert W. Elder ◽  
Jan M. Quaegebeur ◽  
Emile A. Bacha ◽  
Jonathan M. Chen ◽  
Francois Bourlon ◽  
...  


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