Low-Grade Fibromatosis-Like Spindle Cell Metaplastic Carcinoma of the Breast: A Case Report and Literature Review

Introduction. Metaplastic breast carcinoma is expressing epithelial and/or mesenchymal tissue within the same tumor. Aim. The aim of this study is to evaluate metaplastic breast carcinoma in a case report and literature review. Description of the case. The presented case desribes metaplastic carcinoma of the breast in 65 years old female patient. Conclusion. Fibromatosis-cell metaplastic carcinoma of the breast presents a particularly large diagnostic challenge. Malignant variants of this disease have been described in the literature.

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Metaplastic carcinoma of the breast: a case report and literature review

Research ◽

10.13070/rs.en.1.758 ◽

2014 ◽

Vol 1 ◽

Author(s):

Erdinc Kamer ◽

Oğuz Hancerliogullari ◽

Ayşegul Akder Sari ◽

Ilker Kiziloglu ◽

Mustafa Peskersoy

Keyword(s):

Case Report ◽

Literature Review ◽

Metaplastic Carcinoma ◽

Carcinoma Of The Breast

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Metaplastic Carcinoma of the Breast with High Grade Spindle Cell Component with Osteoid Formation—a Rare Case Report

Acta Chirurgica Belgica ◽

10.1080/00015458.2011.11680747 ◽

2011 ◽

Vol 111 (4) ◽

pp. 243-245 ◽

Cited By ~ 1

Author(s):

R. Singal ◽

P. Singh ◽

P. Sahu ◽

A. Mittat ◽

B. Naredi ◽

...

Keyword(s):

Case Report ◽

Rare Case ◽

Spindle Cell ◽

Metaplastic Carcinoma ◽

High Grade ◽

Cell Component ◽

Carcinoma Of The Breast ◽

Spindle Cell Component ◽

Rare Case Report ◽

Osteoid Formation

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Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report

Rare Tumors ◽

10.1177/2036361320977021 ◽

2020 ◽

Vol 12 ◽

pp. 203636132097702 ◽

Cited By ~ 1

Author(s):

April Choi ◽

Philip M Carpenter ◽

Shefali Chopra ◽

Kristi M Lara ◽

William W Tseng ◽

...

Keyword(s):

Breast Cancer ◽

Case Report ◽

Cell Carcinoma ◽

Randomized Trials ◽

Spindle Cell ◽

Spindle Cell Carcinoma ◽

Metaplastic Carcinoma ◽

Cell Type ◽

Carcinoma Of The Breast ◽

Spindle Cell Type

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.

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