scholarly journals Fibromatosis-like spindle-cell metaplastic carcinoma of the breast – a case report

2021 ◽  
Vol 19 (1) ◽  
pp. 98-101
Author(s):  
Michał Osuchowski ◽  
◽  
Dorota Bartusik-Aebisher ◽  
Ewa Kaznowska ◽  
David Aebisher ◽  
...  
Keyword(s):  
Case Report ◽  
Breast Carcinoma ◽  
Literature Review ◽  
Female Patient ◽  
Spindle Cell ◽  
Metaplastic Carcinoma ◽  
Diagnostic Challenge ◽  
Carcinoma Of The Breast ◽  
Mesenchymal Tissue ◽  
Metaplastic Breast Carcinoma

Introduction. Metaplastic breast carcinoma is expressing epithelial and/or mesenchymal tissue within the same tumor. Aim. The aim of this study is to evaluate metaplastic breast carcinoma in a case report and literature review. Description of the case. The presented case desribes metaplastic carcinoma of the breast in 65 years old female patient. Conclusion. Fibromatosis-cell metaplastic carcinoma of the breast presents a particularly large diagnostic challenge. Malignant variants of this disease have been described in the literature.

Low-Grade Fibromatosis-Like Spindle Cell Metaplastic Carcinoma of the Breast: A Case Report and Literature Review

2012 ◽  
Vol 12 (2) ◽  
pp. 147-150 ◽  
Author(s):  
Rita Nonnis ◽  
Panagiotis Paliogiannis ◽  
Daiana Giangrande ◽  
Vincenzo Marras ◽  
Mario Trignano
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Spindle Cell ◽  
Metaplastic Carcinoma ◽  
Low Grade ◽  
Carcinoma Of The Breast

Spindle Cell Metaplastic Breast Carcinoma

2021 ◽  
Vol 17 ◽  
Author(s):  
Vithya Sanmugasiva ◽  
Marlina Tanty Ramli Hamid ◽  
Farhana Fadzli ◽  
Nazimah Ab Mumin ◽  
Kartini Rahmat
Keyword(s):  
Breast Carcinoma ◽  
Cell Carcinoma ◽  
Spindle Cell ◽  
Final Diagnosis ◽  
Spindle Cell Carcinoma ◽  
Left Breast ◽  
Metaplastic Carcinoma ◽  
Breast Cancers ◽  
Breast Lump ◽  
Metaplastic Breast Carcinoma

Introduction: Metaplastic breast carcinoma is an uncommon malignancy that constitutes < 5% of all breast cancers. There are 5 subtypes which are spindle cell, squamous cell, carcinosarcoma, matrix-producing and metaplastic with osteoclastic giant cells. Spindle cell carcinoma represents approximately <0.3% of invasive breast carcinomas. It is typically a triple-negative cancer with distinct pathological characteristics, but relatively a non-conclusive imaging findings. Case report: An elderly lady presented with an enlarging painful left breast lump for 1 year. Palpable left breast lump noted on clinical examination. Mammography demonstrated a high density, oval lesion with a partially indistinct margin. Corresponding ultrasound showed a large irregular heterogeneous lesion with solid-cystic areas. Histopathology showed atypical spindle-shaped cells which stained positive for cytokeratins and negative for hormone and human epidermal growth factor receptors, which favours spindle cell metaplastic carcinoma. Left mastectomy and axillary dissection were performed, and the final diagnosis was consistent with metaplastic spindle cell carcinoma. Conclusion: Spindle cell carcinoma of the breast is a rare aggressive histological type of carcinoma which may present with benign features on imaging. Tissue diagnosis is essential for prompt diagnosis with multidisciplinary team discussion to guide management and improve patient’s outcome.

scholarly journals Metaplastic Carcinoma of the Breast with Neuroectodermal Stromal Component

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Tibor Tot ◽  
Juan José Badani De La Parra ◽  
Leif Bergkvist
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Brain Metastases ◽  
Lymph Node Metastases ◽  
Metaplastic Carcinoma ◽  
Unique Case ◽  
Carcinoma Of The Breast ◽  
Stromal Component ◽  
Node Metastases ◽  
Metaplastic Breast Carcinoma

A unique case of metaplastic breast carcinoma with an epithelial component showing tumoral necrosis and neuroectodermal stromal component is described. The tumor grew rapidly and measured 9 cm at the time of diagnosis. No lymph node metastases were present. The disease progressed rapidly and the patient died two years after the diagnosis from a hemorrhage caused by brain metastases. The morphology and phenotype of the tumor are described in detail and the differential diagnostic options are discussed.

scholarly journals Metaplastic carcinoma of the breast: a case report and literature review

Research ◽  
2014 ◽  
Vol 1 ◽  
Author(s):  
Erdinc Kamer ◽  
Oğuz Hancerliogullari ◽  
Ayşegul Akder Sari ◽  
Ilker Kiziloglu ◽  
Mustafa Peskersoy
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Metaplastic Carcinoma ◽  
Carcinoma Of The Breast

scholarly journals Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097702 ◽  
Author(s):  
April Choi ◽  
Philip M Carpenter ◽  
Shefali Chopra ◽  
Kristi M Lara ◽  
William W Tseng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cell Carcinoma ◽  
Randomized Trials ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Metaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Breast ◽  
Spindle Cell Type

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.

scholarly journals Metaplastic breast carcinoma “fibromatosis like”, associated with intraductal papilloma. Case report and literature review

2017 ◽  
Vol 9 ◽  
pp. 15-18 ◽  
Author(s):  
Ignacio Pinilla Pagnon ◽  
Belén Pérez Mies ◽  
Marco Tulio Martinez ◽  
Lourdes Peña Jaimes ◽  
Ana María Roldan Cabanillas ◽  
...  
Keyword(s):  
Case Report ◽  
Breast Carcinoma ◽  
Literature Review ◽  
Intraductal Papilloma ◽  
Metaplastic Breast Carcinoma

scholarly journals Spindle Cell Metaplastic Breast Carcinoma with Leiomyoid Differentiation: A Case Report

Breast Care ◽  
2011 ◽  
Vol 6 (3) ◽  
pp. 230-233 ◽  
Author(s):  
Claudius Conrad ◽  
Diane L. Miller ◽  
Christina Kaiser ◽  
Karl-Walter Jauch ◽  
Hanno Nieß ◽  
...  
Keyword(s):  
Case Report ◽  
Breast Carcinoma ◽  
Spindle Cell ◽  
Metaplastic Breast Carcinoma
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