Efficacy of CT-guided percutaneous needle biopsy in the diagnosis of malignant lymphoma at first presentation

2005 ◽  
Vol 29 (2) ◽  
pp. 123-127 ◽  
Author(s):  
Luca Balestreri ◽  
Sandro Morassut ◽  
Daniele Bernardi ◽  
Marcello Tavio ◽  
Renato Talamini ◽  
...  
Keyword(s):  
Malignant Lymphoma ◽  
Needle Biopsy ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided

Investigation of the Safety and Usefulness of Computed Tomography-Guided Percutaneous Needle Biopsy of Paraaortic Lymph Nodes.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 5027-5027
Author(s):  
Takeshi Aramaki ◽  
Takashi Ikeda ◽  
Michihisa Moriguchi ◽  
Takahiro Tsushima ◽  
Masahiro Endo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Lymph Nodes ◽  
Malignant Lymphoma ◽  
Needle Biopsy ◽  
Percutaneous Biopsy ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided ◽  
Node Metastasis ◽  
Paraaortic Lymph Nodes

Abstract Abstract 5027 Background Various factors such as malignant lymphoma cause abdominal lymph node enlargement. A histological diagnosis of malignant lymphoma is important in planning therapy, and although superficial lymph node biopsies are often obtained, target lesions occasionally arise only around the abdominal aorta. These require surgical, or more recently, endoscopic biopsies. To intraoperatively determine whether target lymph nodes are correctly resected during a surgical biopsy can be difficult, and therapy could be delayed due to postoperative complications. Objective To assess the safety and effectiveness of percutaneous biopsy of paraaortic lymph nodes under computed tomography (CT) fluoroscopic guidance. Subjects and Methods We retrospectively investigated puncture success rates based on findings of diagnostic imaging, size of target lymph nodes, rate of confirmed diagnosis, frequency of changes in therapeutic plans and incidence of complications among 36 patients after percutaneous needle biopsy using an 18G cutting needle between September 2002 and March 2009. Results The pre-biopsy diagnoses for the 36 subjects who underwent percutaneous needle biopsy included: malignant lymphoma (n = 26), lymph node metastasis of esophageal cancer (n = 3), lymph node metastasis of lung cancer (n = 3), lymph node metastasis of pancreatic cancer (n = 3) and unknown (n = 3). The median size of the target lymph nodes was 25 mm (range: 9–102 mm). The results of diagnostic imaging indicated that all punctures were successful. The diagnoses were confirmed in 33 of the 36 patients (91.7%). Histopathological findings confirmed malignant lymphoma (n = 21; Follicular Lymphoma in 11 patients, Diffuse Large B cell Lymphoma in 8, T-Cell Lymphoma in 1, Hodgkin Disease in 1), squamous cell carcinoma (n = 2), poorly differentiated adenoma (n = 2), other malignancies (n = 5), benign lesions (n = 3) and unknown in 3. Therapeutic strategies were altered based on the results of CT-guided percutaneous needle biopsies in 12 of the 36 patients (33.3%). Three patients developed 4 adverse events comprising grade 1 radiation dermatitis (n = 1), grade 1 hematoma (n = 2) and grade 1 pneumothorax (n = 1). Conclusions Target paraaortic lymph nodes can be accurately punctured using CT-guided percutaneous needle biopsy, and the specimens were too small to examine the flowcytometry or chromosome analysis, however it was enough to confirmed the diagnosis according to WHO classification of malignant lymphoma. Percutaneous biopsy of paraaortic lymph nodes under CT fluoroscopic guidance is useful for confirming diagnoses with a low risk of serious deep organ damage. Disclosures No relevant conflicts of interest to declare.

scholarly journals Value of CT-guided percutaneous needle biopsy of bone in the diagnosis of lymphomas based on PET/CT results

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Zhiwei Wang ◽  
Haifeng Shi ◽  
Xiaobo Zhang ◽  
Jie Pan ◽  
Zhengyu Jin
Keyword(s):  
Needle Biopsy ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided ◽  
Pet Ct

scholarly journals Feasibility and accuracy of CT-guided percutaneous needle biopsy of cavitary pulmonary lesions

2019 ◽  
Vol 25 (6) ◽  
pp. 435-441 ◽  
Author(s):  
Nantaka Kiranantawat ◽  
◽  
Milena Petranovic ◽  
Shaunagh McDermott ◽  
Matthew Gilman ◽  
...  
Keyword(s):  
Needle Biopsy ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided ◽  
Pulmonary Lesions

scholarly journals Computed tomography–guided percutaneous biopsy for vertebral neoplasms: a department's experience and hybrid biopsy technique to improve yield

2016 ◽  
Vol 41 (2) ◽  
pp. E17 ◽  
Author(s):  
Vasant Garg ◽  
Christos Kosmas ◽  
Enambir S. Josan ◽  
Sasan Partovi ◽  
Nicholas Bhojwani ◽  
...  
Keyword(s):  
Needle Biopsy ◽  
Core Biopsy ◽  
Diagnostic Yield ◽  
Vertebral Osteomyelitis ◽  
Radiology Department ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided ◽  
Biopsy Technique ◽  
Significant Difference ◽  
Higher Sensitivity

OBJECTIVE Recent articles have identified the poor diagnostic yield of percutaneous needle biopsy for vertebral osteomyelitis. The current study aimed to confirm the higher accuracy of CT-guided spinal biopsy for vertebral neoplasms and to identify which biopsy technique provides the highest yield. METHODS Over a 9-year period, the radiology department at University Hospitals Case Medical Center performed 222 CT-guided biopsies of vertebral lesions, of which clinicians indicated a concern for vertebral neoplasms in 122 patients. A retrospective chart review was performed to confirm the higher sensitivity of the percutaneous intervention for vertebral neoplasms. RESULTS A core sample was obtained for all 122 biopsies of concern (100.0%). Only 6 cases (4.9%) were reported as nondiagnostic per histological sampling, and 12 cases (9.8%) were negative for disease. The question of vertebral neoplastic involvement warrants follow-up, and the current study was able to determine the subsequent diagnosis of each lesion. Of the 122 total, 94 (77.0%) core samples provided true-positive results, and the sensitivity of core biopsy measured 87.9%. The technical approach did not demonstrate any significant difference in diagnostic yield. However, when the vertebral cortex was initially pierced with a coaxial bone biopsy system and subsequently a 14-gauge spring-loaded cutting biopsy needle was coaxially advanced into lytic lesions, 14 true positives were obtained with a corresponding sensitivity of 100.0%. CONCLUSIONS This study confirms the higher sensitivity of image-guided percutaneous needle biopsy for vertebral neoplasms. In addition, it demonstrates how the use of a novel cutting needle biopsy approach, performed coaxially through a core biopsy track, provides the highest yield.

scholarly journals PRIMARY MALIGNANT LYMPHOMA IN THE POSTERIOR MEDIASTINUM DIAGNOSED BY CT-GUIDED NEEDLE BIOPSY

1990 ◽  
Vol 40 (5) ◽  
pp. 647-651
Author(s):  
YOSHITO TSUSHIMA ◽  
MITSUOMI MATSUMOTO ◽  
NORIKO SATO ◽  
KUNIAKI TOMIOKA ◽  
TATSUYA KATO ◽  
...  
Keyword(s):  
Malignant Lymphoma ◽  
Needle Biopsy ◽  
Posterior Mediastinum ◽  
Ct Guided

Pathological Examination and Differential Diagnosis of Pulmonary Ground-Glass Opacities by CT-Guided Percutaneous Needle Biopsy

2021 ◽  
Vol 11 (3) ◽  
pp. 912-920
Author(s):  
Yong Li ◽  
Yanxin Sun ◽  
Jingqi Han ◽  
Hualong Yu ◽  
Chuanyu Zhang ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Needle Biopsy ◽  
Ground Glass ◽  
Bronchioloalveolar Carcinoma ◽  
Pathological Examination ◽  
Special Treatment ◽  
Percutaneous Needle Biopsy ◽  
Pulmonary Tissue ◽  
Ct Guided ◽  
Sensitivity Specificity

In order to explore the pathological examination and differential diagnosis of pulmonary ground-glass opacities (GGO) with CT-guided percutaneous needle biopsy (CTPNB), this study retrospectively analyzed the medical records of 120 cases of patients who were diagnosed with pulmonary GGO and underwent CTPNB in a hospital designated by this study from December 2014 to December 2018. The results showed that all the 120 cases of patients were successfully punctured at one time and obtained sufficient tissue specimens with the puncture success rate and diagnostic accuracy both of 100%, being able to make a clear qualitative diagnosis. Among them, 30 cases were malignant lesions including 14 cases of bronchioloalveolar carcinoma and 16 cases of metastatic carcinoma; 90 cases were benign lesions including 52 cases of hematogenous pulmonary tuberculosis, 14 cases of sarcoidosis, 12 cases of silicosis and coal workers’ pneumoconiosis, 6 cases of interstitial pneumonia, 4 cases of alveolar proteinosis, and 2 case of allergic pneumonia. The complications of the 120 patients during the treatment included 8 cases of pneumothorax with an incidence of 6.67% (8/120), in which 2 case had the pulmonary tissue compression rate of about 25% and the other cases had no obvious perceived symptoms and required no special treatment, and 10 cases of hemoptysis with an incidence of 8.33% (10/120), whose symptoms disappeared after the treatment with batroxobin, and had no serious symptoms such as air embolism complication. The sensitivity, specificity, and accuracy of CTPNB in the diagnosis of malignant pulmonary GGO were 83.67% (82/98), 100% (22/22), and 86.67% (104/120), respectively, without statistically significant differences in diagnostic efficacy (P > 0.05). In summary, the CTPNB for the diagnosis of malignant pulmonary GGO has high sensitivity, specificity, and accuracy, and the CTPNB is also the simplest and most important approach to obtain effective pathological examinations and differential diagnoses of pulmonary GGO, which has simple operation, high accuracy and few complications, and has high application value for the qualitative diagnosis of pulmonary GGO.

scholarly journals CT guided percutaneous needle biopsy of the chest: initial experience

2016 ◽  
Vol 23 ◽  
Author(s):  
Younes Lazguet ◽  
Rachid Maarouf ◽  
Marouan Karrou ◽  
Imane Skiker ◽  
Ihsan Alloubi
Keyword(s):  
Needle Biopsy ◽  
Initial Experience ◽  
Percutaneous Needle Biopsy ◽  
Ct Guided
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