Relationship Between Pain Relief and Improvements in Patient Function/Quality of Life in Patients With Painful Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Treated With Pregabalin

2013 ◽  
Vol 35 (5) ◽  
pp. 612-623 ◽  
Author(s):  
Aaron Vinik ◽  
Birol Emir ◽  
Raymond Cheung ◽  
Ed Whalen
2015 ◽  
Vol 39 (1) ◽  
pp. 17-28 ◽  
Author(s):  
Casandra J Rosenberg ◽  
James C Watson

Background: Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Objective: To discuss current treatment recommendations for painful diabetic peripheral neuropathy. Study design: Literature review. Methods: Systematic review of the literature discussing treatment of painful diabetic peripheral neuropathy. Existing treatment guidelines were studied and compared. Results: Painful diabetic peripheral neuropathy occurs in about one in six people with diabetes. This condition impairs quality of life and increases healthcare costs. Treatment recommendations exist, but individual patient therapy can require a trial-and-error approach. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control. Adequate medication titration and a reasonable trial period should be allowed. Conclusion: The treatment of painful diabetic peripheral neuropathy can be challenging, but effective management can improve patient’s quality of life. Clinical relevance Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2209-PUB
Author(s):  
CHANDNI RADHAKRISHNAN ◽  
ANJUSHA UT ◽  
SREEJITH K ◽  
NEERAJ MANIKATH ◽  
RINU R. CR

Author(s):  
Nishitha Chowdary Dl ◽  
Somasundaram I

Objectives: The objectives of the study were to study the prevalence of painful diabetic peripheral neuropathy (PDPN) in patients with type-2 diabetes and to access the health-related quality of life of patient by collecting and documenting the information of patient using sf-15 questionnaire.Methods: The present study involves prospective analysis of quality of life in both men and women with PDPN with type-2 diabetes. The methodology involves collection and documentation of patients medical and medication history, blood glucose levels, and duration of diabetes. Further, the quality of life of patient is documented using Michigan neuropathic scaling instrument (sf-15 questionnaire) through which we can assess the impact of PDPN.Results: It can be seen that there are no significant changes in the prevalence of PDPN when compared gender wise and based on age, but there are an extremely statistically significant (*p<0.05) values obtained when the presence of PDPN is compared between duration of diabetes.Conclusion: Patients with duration of diabetes type-2 between 5 and 10 years are mostly presented with PDPN. Early detection, nutritious diet, and patient counseling help in management of PDPN.


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