scholarly journals Candida post gram-negative line sepsis in patients on Home Parenteral Nutrition: A study of 32 patients

2015 ◽  
Vol 10 (5) ◽  
pp. e209-e210
Author(s):  
V. Evans ◽  
A. Hughes ◽  
D. Forbes-Penfold ◽  
J. Koeglmeier ◽  
S. Hill
Keyword(s):  
Parenteral Nutrition ◽  
Home Parenteral Nutrition ◽  
Gram Negative ◽  
Line Sepsis

scholarly journals A240 HOME PARENTERAL NUTRITION IN OLDER VERSUS YOUNGER PATIENTS: CLINICAL CHARACTERISTICS AND OUTCOMES

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 295-296
Author(s):  
D Daoud ◽  
E M S Cartagena ◽  
N Somlaw ◽  
K Schwenger ◽  
L Gramlich ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parenteral Nutrition ◽  
Older Patients ◽  
Clinical Characteristics ◽  
Karnofsky Performance Status ◽  
Group Versus ◽  
Home Parenteral Nutrition ◽  
Younger Patients ◽  
Line Sepsis

Abstract Background There is a demographic shift toward older patients receiving home parenteral nutrition (HPN) but there is little data on their clinical characteristics and outcomes versus younger HPN patients. Aims The objective of this study was to determine if there are any differences between older (> 60 years) and younger (18–59 years) HPN patients in regard to HPN indications, prescriptions and outcomes over the first 2 years receiving HPN. Methods This was a retrospective analysis of prospectively collected data from HPN adult patients entered in the password protected web-based Canadian HPN Registry. New HPN patients enrolled between 2003 and 2017 and receiving HPN for 2 years were selected from 8 participating programs across Canada. Data included demographics, anthropometrics, PN prescriptions, line sepsis events, survival and quality of life based on the Karnofsky Performance Status (KPS). Results 402 patients met the inclusion criteria: 184 patients were 60 years old or above (older group) and 219 patients were between 18 and 59 years old (younger group). Around 64% of both groups were female. There were no significant differences in the main indications for HPN, body mass index (BMI), and PN prescriptions at baseline. At 2-years, younger patients received more calories from PN than older patients (27.88 vs 19.56 Kcal/kg respectively, p <0.001) but BMI remained comparable between groups. There were less line sepsis in the older group versus the younger group (20% vs 36%, p=0.0023) but 78% of younger patients remained alive versus 69 % in the older group (p=0.0401). In those alive, the proportion of patients remaining on HPN was comparable (older group: 77%; younger; group 81%, p=0.4709) and the proportion of patients with a reasonable quality of life (KPS > 60) was similar (older group: 58%; younger group: 63%, p=0.2156). Conclusions Older HPN patients have similar clinical characteristics as younger patients but with reduced line sepsis events and higher 2-year mortality. Funding Agencies Ontario Medical Supply, Takeda, Fresenius Kabi and Baxter Inc

Line Sepsis in Home Parenteral Nutrition Patients: Are There Socioeconomic Risk Factors? A Canadian Study

2005 ◽  
Vol 29 (6) ◽  
pp. 408-412 ◽  
Author(s):  
Albert Chang ◽  
Robert Enns ◽  
Olivia Saqui ◽  
Nazira Chatur ◽  
Scott Whittaker ◽  
...  
Keyword(s):  
Risk Factors ◽  
Parenteral Nutrition ◽  
Home Parenteral Nutrition ◽  
Canadian Study ◽  
Socioeconomic Risk ◽  
Line Sepsis ◽  
Socioeconomic Risk Factors

Initial experiences in and difficulties with home parenteral nutrition

2014 ◽  
Vol 52 (05) ◽  
Author(s):  
A Rudas ◽  
A Domán ◽  
Á Sárkány ◽  
J Gervain ◽  
O Nyikos ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Home Parenteral Nutrition

Retraining of home parenteral nutrition (HPN) users in Australia and New Zealand: a consumer audit

2019 ◽  
Vol 5 (2) ◽  
pp. 29-37
Author(s):  
Karen Winterbourn ◽  
Chris Walker ◽  
Miranda Einstein ◽  
Gillian Anderson ◽  
Fay Boyd
Keyword(s):  
New Zealand ◽  
Parenteral Nutrition ◽  
Home Parenteral Nutrition

scholarly journals Incidence and Outcomes of Home Parenteral Nutrition in Patients With Crohn Disease in Olmsted County, Minnesota

2020 ◽  
Vol 2 (4) ◽  
Author(s):  
Zeinab Bakhshi ◽  
Siddhant Yadav ◽  
Bradley R Salonen ◽  
Sara L Bonnes ◽  
Jithinraj Edakkanambeth Varayil ◽  
...  
Keyword(s):  
Weight Loss ◽  
Parenteral Nutrition ◽  
Short Bowel Syndrome ◽  
Crohn Disease ◽  
Severe Disease ◽  
Bloodstream Infections ◽  
Home Parenteral Nutrition ◽  
Average Weight ◽  
Olmsted County ◽  
Short Bowel

Abstract Background We sought to estimate the incidence of home parenteral nutrition (HPN) use in a population-based cohort of patients with Crohn disease (CD), and to assess clinical outcomes and complications associated with HPN. Methods We used the Rochester Epidemiology Project (REP) to identify residents of Olmsted County, who were diagnosed with CD between 1970 and 2011, and required HPN. Results Fourteen out of 429 patients (3.3%) with CD received HPN (86% female). Eleven patients (79%) had moderate–severe CD and 12 patients (86%) had fistulizing disease. Thirteen patients (93%) underwent surgery, primarily due to obstruction. Among CD incidence cases, the cumulative incidence of HPN from the date of CD diagnosis was 0% at 1 year, 0.5% at 5 years, 0.8% at 10 years, and 2.4% at 20 years. Indications for HPN included short bowel syndrome in 64%, malnutrition in 29%, and bowel rest in 21%. The median duration of HPN was 2.5 years. There was an average weight gain of 1.2 kg at 6 months, an average weight loss of 1.4 kg at 1 year, and a further weight loss of 2.2 kg at 2 years from the start of HPN. Patients were hospitalized a mean of 5 times after the start of HPN, mainly due to catheter-related bloodstream infections and thrombosis. Conclusions Less than 4% of patients with CD need HPN. Most have moderate to severe disease with short bowel syndrome or malnutrition. Possible reasons for the patients’ weight loss could be noncompliance, and increased metabolic needs because of active disease.

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