Sarcopenia determined by hand grip strength and calf circumference as predictor of mortality in older inpatients with hip fracture

2021 ◽  
Vol 46 ◽  
pp. S577
Author(s):  
F.J.Sanchez Torralvo ◽  
M. García Olivares ◽  
V. Pérez del Río ◽  
J. Abuín Fernández ◽  
G. Olveira
2013 ◽  
Vol 8 (1-2) ◽  
Author(s):  
Dinesh K. Dhanwal ◽  
Pramila Dharmshaktu ◽  
V. K. Gautam ◽  
N. Gupta ◽  
Alpana Saxena

PLoS ONE ◽  
2019 ◽  
Vol 14 (8) ◽  
pp. e0213223 ◽  
Author(s):  
Ivan Selakovic ◽  
Emilija Dubljanin-Raspopovic ◽  
Ljiljana Markovic-Denic ◽  
Vuk Marusic ◽  
Andja Cirkovic ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2243 ◽  
Author(s):  
Vincenzo Malafarina ◽  
Concetta Malafarina ◽  
Arantzazu Biain Ugarte ◽  
J. Alfredo Martinez ◽  
Itziar Abete Goñi ◽  
...  

Background: Admitted bedridden older patients are at risk of the development of sarcopenia during hospital stay (incident sarcopenia). The objective of this study was to assess the factors associated with sarcopenia (incident and chronic) and its impact on mortality in older people with hip fracture. Methods: A multicenter, pragmatic, prospective observational study was designed. Older subjects with hip fracture admitted to two rehabilitation units were included. Sarcopenia was assessed at admission and at discharge according to the revised EWGSOP (European Working Group on Sarcopenia in Older People) consensus definition. The mortality was evaluated after 7 years of follow-up. Results: A total of 187 subjects (73.8% women) age 85.2 ± 6.3 years were included. Risk factors associated to incident and chronic sarcopenia were undernutrition (body mass index—BMI and Mini Nutritional Assessment−Short Form—MNA-SF), hand-grip strength and skeletal muscle index. During follow-up 114 patients died (60.5% sarcopenic vs. 39.5% non-sarcopenic, p = 0.001). Cox regression analyses showed that factors associated to increased risk of mortality were sarcopenia (HR: 1.67, 95% CI 1.11–2.51) and low hand-grip strength (HR: 1.76, 95% CI 1.08–2.88). Conclusions: Older patients with undernutrition have a higher risk of developing sarcopenia during hospital stay, and sarcopenic patients have almost two times more risk of mortality than non-sarcopenic patients during follow-up after hip fracture.


2018 ◽  
Vol 111 ◽  
pp. 1-9 ◽  
Author(s):  
Katharina Denk ◽  
Sheila Lennon ◽  
Susan Gordon ◽  
Ruurd Lucas Jaarsma

2019 ◽  
Author(s):  
Ivan Selakovic ◽  
Emilija Dubljanin-Raspopovic ◽  
Ljiljana Markovic-Denic ◽  
Vuk Marusic ◽  
Andja Cirkovic ◽  
...  

AbstractDecreased muscle strength is not only a risk factor for hip fracture in elderly patients, but plays a role in recovery of physical function. Our aim was to assess the role of grip strength measured early after hip fracture, and classified according to the EWGSOP2 criteria in predicting short- and long-term functional recovery. One hundred ninety-one patients with acute hip fracture consecutively admitted to an orthopaedic hospital have been selected. A multidimensional geriatric assessment evaluating sociodemographic variables, cognitive status, functional status and quality of life prior to fracture, as well as perioperative variables were performed. Follow-ups at 3 and 6 months after surgery were carried out to evaluate functional recovery. Multivariate regression models were used to assess the predictive role of handgrip strength. The mean age of the participants was 80.3 ±6.8 years. Thirty-five percent of our patients with clinically relevant hand grip strength weakness were significantly older, more often female, had a lower BMI, and were of worse physical health. They also had a lower cognitive level, lower Barthel index, and lower EQ5D scores before fracture. Multivariate regression analysis adjusted for age and gender revealed that hand grip weakness was an independent predictor of worse functional outcome at 3 and 6 months after hip fracture for both genders and in all age populations. Our study supports the prognostic role of hand grip strength assessed at hospital admission in patients with hip fracture. Thus, clinicians should be encouraged to include hand grip assessment in their evaluation of hip fracture patients in the acute setting in order to optimize treatment of high-risk individuals.


2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Hugo Gutiérrez-Hermosillo ◽  
Enrique Díaz de León-González ◽  
Juan Humberto Medina-Chávez ◽  
Francisco Torres-Naranjo ◽  
Claudia Martínez-Cordero ◽  
...  

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Bang Yu Xu ◽  
Shi Yan ◽  
Lian Leng Low ◽  
Farhad Fakhrudin Vasanwala ◽  
Sher Guan Low

Abstract Background Hip fracture is an important and prevalent medical condition associated with adverse outcomes. The aim of this article is to systematically review and summarise the predictors of poor functional outcomes and mortality for patients with hip fractures. Methods We conducted a systemic literature search using PubMed, EMBASE and Cochrane Library. We included English peer-reviewed cohort studies that examined predictors of poor functional outcomes (such as independence in Activities of Daily Living) and mortality for patients with hip fracture published in the past 15 years (from 1 Jan 2004 up to 30 May 2019). Two independent researchers evaluated the articles for eligibility. Consensus on the eligibility was sought and a third researcher was involved if there was disagreement. A standardised form was used to extract relevant data. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. Results We retrieved 4339 and included 81 articles. We identified two emerging predictors of poor functional outcomes and mortality for patients with hip fractures: low hand grip strength and frailty in line with an emerging concept of “physical performance”. The predictors identified in this systematic review can be grouped into 1) medical factors, such as presence of co-morbidities, high American Society of Anesthesiologists (ASA) grade, sarcopenia, 2) surgical factors including delay in operation (e.g. > 48 h), type of fracture s, 3) socio-economic factors which include age, gender, ethnicity, and 4) system factors including lower case-volume centers. Conclusions This systematic review identified multiple significant predictors of poor functional outcomes and mortality, with the hand grip strength and frailty being important emerging predictors in the most recent literature. These predictors would further inform healthcare providers of their patients’ health status and allow for early intervention for modifiable predictors.


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