TiO2-based nanomaterials assisted photocatalytic treatment for virus inactivation: perspectives and applications

2021 ◽  
Vol 34 ◽  
pp. 100716
Author(s):  
Ilaria De Pasquale ◽  
Chiara Lo Porto ◽  
Massimo Dell’Edera ◽  
Maria Lucia Curri ◽  
Roberto Comparelli
Keyword(s):  
Virus Inactivation

“In vitro” and in Animal Model Studies on a Double Virus- Inactivated Factor VIII Concentrate

1995 ◽  
Vol 74 (03) ◽  
pp. 868-873 ◽  
Author(s):  
Silvana Arrighi ◽  
Roberta Rossi ◽  
Maria Giuseppina Borri ◽  
Vladimir Lesnikov ◽  
Marina Lesnikov ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Animal Model ◽  
Factor Viii ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Virus Inactivation ◽  
Enveloped Viruses ◽  
Model Studies ◽  
Heat Treated

SummaryTo improve the safety of plasma derived factor VIII (FVIII) concentrate, we introduced a final super heat treatment (100° C for 30 min) as additional virus inactivation step applied to a lyophilized, highly purified FVIII concentrate (100 IU/mg of proteins) already virus inactivated using the solvent/detergent (SID) method during the manufacturing process.The efficiency of the super heat treatment was demonstrated in inactivating two non-lipid enveloped viruses (Hepatitis A virus and Poliovirus 1). The loss of FVIII procoagulant activity during the super heat treatment was of about 15%, estimated both by clotting and chromogenic assays. No substantial changes were observed in physical, biochemical and immunological characteristics of the heat treated FVIII concentrate in comparison with those of the FVIII before heat treatment.

Riboflavin Surface Modification of Poly(vinyl chloride) for Light-Triggered Control of Bacterial Biofilm and Virus Inactivation

2021 ◽  
Author(s):  
Marcelo Munoz ◽  
Antony El-khoury ◽  
Cagla Eren Cimenci ◽  
Mayte Gonzalez-Gomez ◽  
Robert A. Hunter ◽  
...  
Keyword(s):  
Surface Modification ◽  
Vinyl Chloride ◽  
Bacterial Biofilm ◽  
Virus Inactivation ◽  
Poly Vinyl Chloride

scholarly journals Influence of excipients in Protein a chromatography and virus inactivation

2021 ◽  
pp. 122848
Author(s):  
Carolin Stange ◽  
Supriyadi Hafiz ◽  
Christoph Korpus ◽  
Romas Skudas ◽  
Christian Frech
Keyword(s):  
Protein A ◽  
Virus Inactivation

Enveloped virus inactivation using neutral arginine solutions and applications in therapeutic protein purification processes

2013 ◽  
Vol 30 (1) ◽  
pp. 108-112 ◽  
Author(s):  
Justin T. McCue ◽  
Keith Selvitelli ◽  
Doug Cecchini ◽  
Rhonda Brown
Keyword(s):  
Protein Purification ◽  
Therapeutic Protein ◽  
Virus Inactivation ◽  
Enveloped Virus

Virus Inactivation During Phosphate Precipitation

1970 ◽  
Vol 96 (2) ◽  
pp. 365-379
Author(s):  
Dirk R. Brunner ◽  
Otis J. Sproul
Keyword(s):  
Virus Inactivation
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