scholarly journals Laccase-catalyzed surface oxidation of poly(2-hydroxyethyl methacrylate) contact lens hydrogel using polyvinylamine-graft-TEMPO as mediator

2022 ◽  
Vol 46 ◽  
pp. 100581
Author(s):  
Xudong Deng ◽  
Xi Zhang ◽  
Cong He ◽  
Jie Zhang ◽  
Qiang Fu ◽  
...  
2005 ◽  
Vol 28 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Traian V. Chirila ◽  
David A. Morrison ◽  
Zoya Gridneva ◽  
Danielle Meyrick ◽  
Celia R. Hicks ◽  
...  

2013 ◽  
Vol 67 (6) ◽  
pp. 861-870 ◽  
Author(s):  
Aleksandra Debeljkovic ◽  
Lidija Matija ◽  
Djuro Koruga

This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic materials (SL38-A) for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy). The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia) for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.


Lab on a Chip ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 4205-4214
Author(s):  
Yihang Chen ◽  
Shiming Zhang ◽  
Qingyu Cui ◽  
Jiahua Ni ◽  
Xiaochen Wang ◽  
...  

Microchannels created in poly-2-hydroxyethyl methacrylate (poly(HEMA)) hydrogels have the potential to prevent dry-eye disease by facilitating tear exchange. Biosensors are further demonstrated for wearable biosensing applications.


Soft Matter ◽  
2016 ◽  
Vol 12 (4) ◽  
pp. 1145-1157 ◽  
Author(s):  
Gehong Su ◽  
Tao Zhou ◽  
Yanyan Zhang ◽  
Xifei Liu ◽  
Aiming Zhang

A good understanding of the microdynamics of the water absorption of poly(2-hydroxyethyl methacrylate) (PHEMA)-based contact lens is significant for scientific investigation and commercial applications.


2018 ◽  
Vol 29 (4) ◽  
pp. 1227-1233 ◽  
Author(s):  
Mohammad Kazemi Ashtiani ◽  
Mojgan Zandi ◽  
Parvin Shokrollahi ◽  
Morteza Ehsani ◽  
Hossein Baharvand

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1639
Author(s):  
You-Cheng Chang ◽  
Chen-Ying Su ◽  
Chia-Hua Chang ◽  
Hsu-Wei Fang ◽  
Yang Wei

The ocular discomfort is the leading cause of contact lens wear discontinuation. Although the tear proteins as a lubricant might improve contact lens adaptation, some in vitro studies suggested that the amount of adsorbed proteins could not simply explain the lubricating performance of adsorbed proteins. The purpose of this study was to quantify the structural changes and corresponding ocular lubricating properties of adsorbed protein on a conventional contact lens material, poly (2-hydroxyethyl methacrylate) (pHEMA). The adsorption behaviors of lysozyme on pHEMA were determined by the combined effects of protein–surface and protein–protein interactions. Lysozyme, the most abundant protein in tear, was first adsorbed onto the pHEMA surface under widely varying protein solution concentrations to saturate the surface, with the areal density of the adsorbed protein presenting different protein–protein effects within the layer. These values were correlated with the measured secondary structures, and corresponding friction coefficient of the adsorbed and protein covered lens surface, respectively. The decreased friction coefficient value was an indicator of the lubricated surfaces with improved adaptation. Our results indicate that the protein–protein effects help stabilize the structure of adsorbed lysozyme on pHEMA with the raised friction coefficient measured critical for the innovation of contact lens material designs with improved adaptation.


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