Review of antibiotic use in respiratory disorders at a regional hospital in Queensland

2016 ◽  
Vol 23 (4) ◽  
pp. 391-395 ◽  
Author(s):  
Colleen McGoldrick ◽  
Thomas Ulahannan ◽  
Katrina Lane Krebs
BMC Surgery ◽  
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Gona Jaafar ◽  
Bahman Darkahi ◽  
Lars Lindhagen ◽  
Gunnar Persson ◽  
Gabriel Sandblom

2015 ◽  
Vol 17 (3) ◽  
Author(s):  
Jaffu Chilongola ◽  
Elizabeth Msoka ◽  
Adinan Juma ◽  
Elimsaada Kituma ◽  
Edith Kwigizile ◽  
...  

Background: Irrational antibiotic use is an important factor for development and spread of resistance to currently used antibiotics. This study was carried out to assess antibiotic prescribing practices among cases diagnosed as malaria at three hospitals in Moshi Municipality in northern Tanzania.Methods: This was a cross sectional, retrospective study that included patients files from Kilimanjaro Christian Medical Centre (KCMC), Mawenzi Regional Hospital and St Joseph Hospital. Patient files whose primary provisional diagnosis was malaria were analysed using a convenient sampling method. Variables of interest were the types of medications prescribed, whether or not a laboratory test was requested and treatment was initiated before laboratory reports.Results: A total of 250 patients’ files were included in the analysis (KCMC=62.8%; Mawenzi=23.2%; St. Joseph=14.0%). In 232 (92.8%) prescriptions made in the three hospitals, laboratory tests were requested to confirm diagnoses. Among laboratory tests requested, 89.2% were blood slides for microscopic detection of malaria parasites, 3.01% malaria rapid diagnostic tests and 3.01% other tests. The majority of prescriptions across all three hospitals (KCMC=86.4%; Mawenzi=91.4%; St. Joseph= 72.4%; X2=7.787). Clinicians at Mawenzi were more likely to start treatment before laboratory findings than their counterparts at KCMC and St Joseph hospitals (X2=7.787, p≤0.05). A significantly higher number of prescriptions made before laboratory findings were observed at KCMC than Mawenzi and St. Joseph hospitals (X2=7.787, p<0.05). Prescriptions from KCMC were more likely to include at least one type of antibiotic than in the other two facilities. Over one third (KCMC=34.0%; St. Joseph=42.1%; Mawenzi=38.1%) of the prescriptions made contained at least one type of an antibiotic. There was a strong association between health facilities and antibiotics prescription in which KCMC prescribed antibiotics at the highest rate while Mawenzi Regional Hospital prescribed antibiotics at the lowest rates (X2=29.234, p<0.001).Conclusion: Antibiotics are prescribed at a high rate among provisionally diagnosed malaria cases before availability of laboratory results. Efforts should be made to improve laboratory services in terms of trained personnel and equipment to reduce irrational use of antibiotics in provisionally diagnosed malaria cases.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Nyambura Moremi ◽  
Vitus Silago ◽  
Erick G. Mselewa ◽  
Ashery P. Chifwaguzi ◽  
Mariam M. Mirambo ◽  
...  

Abstract Objective The objective of this study was to determine the proportion of extended spectrum β-lactamase producing gram-negative bacteria (ESBL-GNB) colonizing patients admitted at Mazimbu hospital and Morogoro Regional hospital, in Morogoro, Tanzania. Rectal colonization with ESBL-GNB increases the risks of developing bacterial infections by extra-intestinal pathogenic ESBL-GNB. Results Of the 285 patients investigated, 123 (43.2%) carried ESBL-GNB in their intestines. Five of the 123 ESBL positive patients were colonized with two different bacteria, making a total of 128 ESBL producing isolates. Escherichia coli (n = 95, 74.2%) formed the majority of ESBL isolates. The proportion of CTX-M-1 group genes among ESBL isolates tested was 94.9% (93/98). History of antibiotic use (OR: 1.83, 95% CI: 1.1–3.2, P = 0.03), being on antibiotic treatment (OR: 2.61, 95% CI: 1.5–4.53, P = 0.001), duration of hospital stay (OR: 1.2, 95% CI: 1.1–1.3, P < 0.001) and history of previous admission (OR: 2.24, 95% CI: 1.2–4.1, P = 0.009) independently predicted ESBL-GNB carriage.


2021 ◽  
Vol 14 (SUPPLEMENT 1) ◽  
pp. 1-7
Author(s):  
Lucyna Sochocka

Background: Preterm birth, defined as the birth of an infant before 37 complete weeks of gestation, is the single major cause of death and disability in children up to 5 years of age in the developed world. Aim of the study: The study aimed at analyzing select adaptation disorders in newborns delivered between 34–37 weeks of gestation and in particular, (1) determining the frequency of breathing, thermoregulatory, hypoglycemic and pathological hepatic disorders, and (2) examining underlying factors that determine their incidence. Material and methods: The study was carried out according to the documentoscopy on the basis of medical files collected between 2019–2020 at the Neonatal and Preterm Baby Unit in WS SPZOZ (the regional hospital) in Nowa Sól. The records of 102 preterm newborn patients were examined, which included the birth book, detailed newborn observation charts, fever charts and individual patient observation charts. Results: The most commonly diagnosed disorders included hepatitis (21.6%; 50) and thermoregulation disorders (20.3%; 47). Additionally, hypoglycemia and tachypnea were observed in every third child (31.4% and 29.4%, respectively) and almost every fourth newborn experienced some respiratory disorders (23.5%). Among the findings, maternal and gestational age were not found to be statistically significant with respect to an association with the incidence of the disorders examined in the study. However, hepatitis was more frequently diagnosed among naturally born children (64.5%) compared with those delivered by Cesarean (C) section (42.3%, p=0.039). Respiratory disorders were more often found in children delivered by C-section (21.1%) than in those born naturally (3.2%, p=0.022). Conclusions: Hepatitis and thermoregulatory disorders occurred most frequently in preterm infants of all the adaptation disorders examined. The type of delivery was quite determinant for some of the disorders. Hepatitis was found more often in naturally born babies than in those delivered by C-section, whereas respiratory problems occurred more frequently in children delivered by C-section compared with those delivered naturally. Mothers who wish to deliver their babies by C-section should be informed about potential complications associated with the occurrence of respiratory disorders. They can stem from the absorption of pulmonary liquid and inappropriate surfactant activity, which can lead to some serious abnormalities related to the improper exchange of respiratory gases.


2018 ◽  
Vol 33 (5) ◽  
Author(s):  
K. Ramchurren ◽  
Y. Balakrishna ◽  
S. Mahomed

Background: Antibiotic resistance is a major public-health problem globally and inappropriate antibiotic use is being increasingly recognised as the main force driving this resistance. Communities can contribute to the reduction of antibiotic resistance by using antibiotics appropriately and as prescribed. The purpose of this study was to assess the knowledge, attitudes and practices of patients regarding antibiotic use at a regional hospital in South Africa.Method: An observational analytic, cross-sectional study was conducted at Prince Mshiyeni Memorial Hospital between May and June 2017. A validated questionnaire consisting of closed-ended questions was administered to outpatients. Patients’ responses were scored and categorised as poor or good for knowledge, attitude and practice.Results: A total of 386 patients were interviewed. Only 205 (53%) patients had a good level of knowledge. Although 270 (70%) patients knew that antibiotics are indicated for the treatment of bacterial infections, 211 (55%) patients incorrectly thought that antibiotics are also used to treat viral infections. Only 168 (44%) patients were aware of the resistance associated with overusing antibiotics. With regard to patients’ attitudes, 164 (42%) patients believed that taking antibiotics for the common cold helped them to recover faster and 178 (46%) patients expected the doctor to prescribe more than one antibiotic for a severe cold. Overall, 157 patients (40%) reported having shared antibiotics with friends or family. Patients with good knowledge were six times more likely to have good antibiotic practices (OR 5.8; 95% CI 0.3–10.6; p 0.001).Conclusion: A well-planned education programme for the public should be undertaken to improve the knowledge and uses of antibiotics among patients.


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