Preparation and characterization of a pH-responsive mesoporous silica nanoparticle dual-modified with biopolymers

2018 ◽  
Vol 548 ◽  
pp. 61-69 ◽  
Author(s):  
Xiaoran Li ◽  
Vasil M. Garamus ◽  
Na Li ◽  
Yabin Gong ◽  
Zhe Zhe ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle

A novel pH-responsive hollow mesoporous silica nanoparticle (HMSN) system encapsulating doxorubicin (DOX) and glucose oxidase (GOX) for potential cancer treatment

2019 ◽  
Vol 7 (20) ◽  
pp. 3291-3302 ◽  
Author(s):  
Kaiwu Cheng ◽  
Yu Zhang ◽  
Yaojia Li ◽  
Zhiguo Gao ◽  
Fanghui Chen ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Glucose Oxidase ◽  
Silica Nanoparticle ◽  
Treatment Modalities ◽  
Materials Chemistry ◽  
Single Treatment ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Hollow Mesoporous Silica ◽  
Potential Cancer

The multi-therapy modality is based on the combination and synergy of multiple single treatment modalities and materials chemistry.

Metal-Phenolic Encapsulated Mesoporous Silica Nanoparticles for pH-Responsive Drug Delivery and Magnetic Resonance Imaging

2018 ◽  
Vol 232 (9-11) ◽  
pp. 1733-1740 ◽  
Author(s):  
Yan Chen ◽  
Juan Wang ◽  
Jianhua Liu ◽  
Lehui Lu
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Burst Release ◽  
Acidic Environment ◽  
Ph Responsive ◽  
Resonance Imaging ◽  
Mesoporous Silica Nanoparticle ◽  
Longitudinal Relaxivity

Abstract The anticancer drug doxorubicin (DOX) is locked in the mesoporous silica nanoparticle by coating FeIII-TA polymer, and its burst release can be achieved under acidic environment, along with the decreased longitudinal relaxivity. This nanoplatform shows great potential to monitoring the drug delivery process and the fate of the nanocarrier.

Zwitterionic carbon dot-encapsulating pH-responsive mesoporous silica nanoparticles for NIR light-triggered photothermal therapy through pH-controllable release

2019 ◽  
Vol 7 (6) ◽  
pp. 2600-2610 ◽  
Author(s):  
Benny Ryplida ◽  
Gibaek Lee ◽  
Insik In ◽  
Sung Young Park
Keyword(s):  
Mesoporous Silica ◽  
Photothermal Therapy ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Carbon Dot ◽  
Image Guided ◽  
Nir Light ◽  
Controllable Release

Here, we designed a pH-responsive Indocyanine Green (ICG)-loaded zwitterionic fluorescent carbon dot (CD)-encapsulating mesoporous silica nanoparticle (MSN) for pH-tunable image-guided photothermal therapy.

Characterization of mesoporous silica nanoparticle composites at low filler content

2015 ◽  
Vol 50 (6) ◽  
pp. 715-722 ◽  
Author(s):  
Qing Yang ◽  
Yuan-Hua Lin ◽  
Ming Li ◽  
Yang Shen ◽  
Ce-Wen Nan
Keyword(s):  
Mesoporous Silica ◽  
Filler Content ◽  
Silica Nanoparticle ◽  
Mesoporous Silica Nanoparticle ◽  
Nanoparticle Composites

Dual pH-responsive mesoporous silica nanoparticles for efficient combination of chemotherapy and photodynamic therapy

2015 ◽  
Vol 3 (23) ◽  
pp. 4707-4714 ◽  
Author(s):  
Xuemei Yao ◽  
Xiaofei Chen ◽  
Chaoliang He ◽  
Li Chen ◽  
Xuesi Chen
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle

By metallo-supramolecular coordinated interaction between Zn-Por and histidine, a dual pH-responsive mesoporous silica nanoparticle (MSN)-based drug delivery system has been fabricated for synergistic chemo-photodynamic therapy.

Preparation and characterization of a dual-receptor mesoporous silica nanoparticle–hyaluronic acid–RGD peptide targeting drug delivery system

RSC Advances ◽  
2016 ◽  
Vol 6 (46) ◽  
pp. 40427-40435 ◽  
Author(s):  
Haixing Xu ◽  
Zhihui Wang ◽  
Yan Li ◽  
Yufeng Guo ◽  
Huimin Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Mesoporous Silica ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Rgd Peptide ◽  
Mesoporous Silica Nanoparticle ◽  
System P ◽  
Peptide Targeting

Novel mesoporous silica nanoparticles conjugated with hyaluronic acid and RGD peptide were developed for dual-receptor mediated targeting drug delivery.

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