Thermo- and pH-responsive, Lipid-coated, Mesoporous Silica Nanoparticle-based Dual Drug Delivery System To Improve the Antitumor Effect of Hydrophobic Drugs

2018 ◽  
Vol 16 (1) ◽  
pp. 422-436 ◽  
Author(s):  
Yi Feng ◽  
Ning-xi Li ◽  
Huan-li Yin ◽  
Tian-yu Chen ◽  
Qian Yang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Drug Delivery System ◽  
Delivery System ◽  
Antitumor Effect ◽  
Silica Nanoparticle ◽  
Hydrophobic Drugs ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Dual Drug

Dual pH-responsive mesoporous silica nanoparticles for efficient combination of chemotherapy and photodynamic therapy

2015 ◽  
Vol 3 (23) ◽  
pp. 4707-4714 ◽  
Author(s):  
Xuemei Yao ◽  
Xiaofei Chen ◽  
Chaoliang He ◽  
Li Chen ◽  
Xuesi Chen
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle

By metallo-supramolecular coordinated interaction between Zn-Por and histidine, a dual pH-responsive mesoporous silica nanoparticle (MSN)-based drug delivery system has been fabricated for synergistic chemo-photodynamic therapy.

Dual-pH-sensitive mesoporous silica nanoparticle-based drug delivery system for tumor-triggered intracellular drug release

2018 ◽  
Vol 53 (15) ◽  
pp. 10653-10665 ◽  
Author(s):  
Hui Chen ◽  
Ying Kuang ◽  
Rong Liu ◽  
Zhongyin Chen ◽  
Bingbing Jiang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Drug Delivery System ◽  
Delivery System ◽  
Silica Nanoparticle ◽  
Ph Sensitive ◽  
Mesoporous Silica Nanoparticle
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