Role of molecular weight and hydrophobicity of amphiphilic tri-block copolymers in temperature-dependent co-micellization process and drug solubility

2019 ◽  
Vol 183 ◽  
pp. 110461 ◽  
Author(s):  
Chin-Fen Lee ◽  
Ching-Hsun Yang ◽  
Tsang-Lang Lin ◽  
Pratap Bahadur ◽  
Li-Jen Chen
Keyword(s):  
Molecular Weight ◽  
Block Copolymers ◽  
Drug Solubility ◽  
Temperature Dependent ◽  
Micellization Process

scholarly journals Adiponectin: Structure, Physiological Functions, Role in Diseases, and Effects of Nutrition

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1180
Author(s):  
Kayvan Khoramipour ◽  
Karim Chamari ◽  
Amirhosein Ahmadi Hekmatikar ◽  
Amirhosein Ziyaiyan ◽  
Shima Taherkhani ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Amino Acids ◽  
Molecular Weight ◽  
Energy Regulation ◽  
Treatment Interventions ◽  
Adipose Tissues ◽  
Physiological Functions ◽  
Cellular Events ◽  
Healthy Nutrition

Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available evidence suggests that adiponectin is involved in a variety of physiological functions, molecular and cellular events, including lipid metabolism, energy regulation, immune response and inflammation, and insulin sensitivity. It has a protective effect on neurons and neural stem cells. Adiponectin levels have been reported to be negatively correlated with cancer, cardiovascular disease, and diabetes, and shown to be affected (i.e., significantly increased) by proper healthy nutrition. The present review comprehensively overviews the role of adiponectin in a range of diseases, showing that it can be used as a biomarker for diagnosing these disorders as well as a target for monitoring the effectiveness of preventive and treatment interventions.

scholarly journals LCST polymers with UCST behavior

Soft Matter ◽  
2021 ◽  
Author(s):  
Marzieh Najafi ◽  
Mehdi Habibi ◽  
Remco Fokkink ◽  
Wim Hennink ◽  
Tina Vermonden
Keyword(s):  
Block Copolymers ◽  
Aqueous Solutions ◽  
Temperature Dependent ◽  
Dependent Behavior ◽  
Temperature Dependent Behavior

In this study, temperature dependent behavior of dense dispersions of core crosslinked flower-like micelles is investigated. Micelles were prepared by mixing aqueous solutions of two ABA block copolymers with PEG...

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