When the long-distance oil pipeline under rivers (referred to as river-crossing pipelines) are damaged by the third-party, they are prone to nudity or left vacant, and the oil pipelines under the action of water flow will cause pipeline failure; and the distance of suspended pipeline is longer than the allowed length will cause the pipeline resonance. In order to avoid pipelines fatigue or broken, suspended pipelines are considered as part of the arc shape, and non-suspended pipelines are considered as the linear shape of the mechanical model with the two ends of the fixed pier synchronous. The study will consider the impact of water flow, buoyancy, the gravity of pipelines and its annexes, bending deformation and bending moment, do the tense calculation for suspended pipelines with external load and the vibration analysis for suspended pipelines under different water flow speeds. The results showed that: the design of river-crossing suspended pipelines not only needs to consider the impact of water flow, buoyancy, the gravity of pipelines and its annexes, bending deformation and bending moment, but also to consider the floating vortex-induced vibration of the suspended pipeline, which should cause pipeline designers, constructors and maintainers’ attention.