scholarly journals Green chemistry approaches towards the design and synthesis of anti-infective fluoroquinolone derivatives

2021 ◽  
Vol 4 ◽  
pp. 100044
Author(s):  
Rajat Goyal ◽  
Archana Sharma ◽  
Vijay Kumar Thakur ◽  
Monika Ola ◽  
Prabodh Chander Sharma
2020 ◽  
Vol 22 (18) ◽  
pp. 6047-6054
Author(s):  
Nicholas R. Babij ◽  
Nakyen Choy ◽  
Megan A. Cismesia ◽  
David J. Couling ◽  
Nicole M. Hough ◽  
...  

The holistic application of Green Chemistry principles in the design and synthesis of the new broad-spectrum fungicide, florylpicoxamid, is described.


2021 ◽  
Vol 6 (10) ◽  
pp. 2483-2491
Author(s):  
Aasia Shaheen ◽  
Uzma Ashiq ◽  
Rifat Ara Jamal ◽  
Khalid Mohammed Khan ◽  
Sana Gul ◽  
...  

Author(s):  
W. Allen Shannon ◽  
José A. Serrano ◽  
Hannah L. Wasserkrug ◽  
Anna A. Serrano ◽  
Arnold M. Seligman

During the design and synthesis of new chemotherapeutic agents for prostatic carcinoma based on phosphorylated agents which might be enzyme-activated to cytotoxicity, phosphorylcholine, [(CH3)3+NCH2CH2OPO3Ca]Cl-, has been indicated to be a very specific substrate for prostatic acid phosphatase (PAP). This phenomenon has led to the development of specific histochemical and ultracytochemical methods for PAP using modifications of the Gomori lead method for acid phosphatase. Comparative histochemical results in prostate and kidney of the rat have been published earlier with phosphorylcholine (PC) and β-glycerophosphate (βGP). We now report the ultracytochemical results.Minced tissues were fixed in 3% glutaraldehyde-0.1 M phosphate buffered (pH 7.4) for 1.5 hr and rinsed overnight in several changes of 0.05 M phosphate buffer (pH 7.0) containing 7.5% sucrose. Tissues were incubated 30 min to 2 hr in Gomori acid phosphatase medium (2) containing 0.1 M substrate, either PC or βGP.


Author(s):  
Mehmet Sarikaya ◽  
Ilhan A. Aksay

Biomimetics involves investigation of structure, function, and methods of synthesis of biological composite materials. The goal is to apply this information to the design and synthesis of materials for engineering applications.Properties of engineering materials are structure sensitive through the whole spectrum of dimensions from nanometer to macro scale. The goal in designing and processing of technological materials, therefore, is to control microstructural evolution at each of these dimensions so as to achieve predictable physical and chemical properties. Control at each successive level of dimension, however, is a major challenge as is the retention of integrity between successive levels. Engineering materials are rarely fabricated to achieve more than a few of the desired properties and the synthesis techniques usually involve high temperature or low pressure conditions that are energy inefficient and environmentally damaging.In contrast to human-made materials, organisms synthesize composites whose intricate structures are more controlled at each scale and hierarchical order.


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