Microenvironmental control of cell fate decisions in mammary gland development and cancer

2021 ◽  
Vol 56 (13) ◽  
pp. 1875-1883
Author(s):  
Gat Rauner ◽  
Charlotte Kuperwasser
Keyword(s):  
Mammary Gland ◽  
Cell Fate ◽  
Mammary Gland Development ◽  
Cell Fate Decisions ◽  
Gland Development

scholarly journals A noncoding RNA is a potential marker of cell fate during mammary gland development

2006 ◽  
Vol 103 (15) ◽  
pp. 5781-5786 ◽  
Author(s):  
M. R. Ginger ◽  
A. N. Shore ◽  
A. Contreras ◽  
M. Rijnkels ◽  
J. Miller ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Cell Fate ◽  
Noncoding Rna ◽  
Mammary Gland Development ◽  
Potential Marker ◽  
Gland Development

scholarly journals Hormones and Mammary Cell Fate—What Will I Become When I Grow Up?

Endocrinology ◽  
2008 ◽  
Vol 149 (9) ◽  
pp. 4317-4321 ◽  
Author(s):  
Heather L. LaMarca ◽  
Jeffrey M. Rosen
Keyword(s):  
Breast Cancer ◽  
Cell Fate ◽  
Progenitor Cell ◽  
Mammary Gland Development ◽  
Hormone Receptors ◽  
Stem Cell Fate ◽  
Cell Fate Decisions ◽  
Mammary Cell ◽  
Mammary Stem ◽  
Gland Development

Systemic hormones are key regulators of postnatal mammary gland development and play an important role in the etiology and treatment of breast cancer. Mammary ductal morphogenesis is controlled by circulating hormones, and these same hormones are also critical mediators of mammary stem cell fate decisions. Recent studies have helped further our understanding of the origin, specification, and fate of mammary stem cells during postnatal development. Here we review recent studies on the involvement of hormone receptors and several transcription factors in mammary stem/progenitor cell differentiation and lineage commitment.

scholarly journals Mammary gland development: cell fate specification, stem cells and the microenvironment

Development ◽  
2015 ◽  
Vol 142 (6) ◽  
pp. 1028-1042 ◽  
Author(s):  
J. L. Inman ◽  
C. Robertson ◽  
J. D. Mott ◽  
M. J. Bissell
Keyword(s):  
Stem Cells ◽  
Mammary Gland ◽  
Cell Fate ◽  
Mammary Gland Development ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
Gland Development
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