scholarly journals Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium

2006 ◽  
Vol 8 (2) ◽  
Author(s):  
Samantha R Oakes ◽  
Heidi N Hilton ◽  
Christopher J Ormandy
2006 ◽  
Vol 103 (15) ◽  
pp. 5781-5786 ◽  
Author(s):  
M. R. Ginger ◽  
A. N. Shore ◽  
A. Contreras ◽  
M. Rijnkels ◽  
J. Miller ◽  
...  

Endocrinology ◽  
2008 ◽  
Vol 149 (9) ◽  
pp. 4317-4321 ◽  
Author(s):  
Heather L. LaMarca ◽  
Jeffrey M. Rosen

Systemic hormones are key regulators of postnatal mammary gland development and play an important role in the etiology and treatment of breast cancer. Mammary ductal morphogenesis is controlled by circulating hormones, and these same hormones are also critical mediators of mammary stem cell fate decisions. Recent studies have helped further our understanding of the origin, specification, and fate of mammary stem cells during postnatal development. Here we review recent studies on the involvement of hormone receptors and several transcription factors in mammary stem/progenitor cell differentiation and lineage commitment.


Development ◽  
2015 ◽  
Vol 142 (6) ◽  
pp. 1028-1042 ◽  
Author(s):  
J. L. Inman ◽  
C. Robertson ◽  
J. D. Mott ◽  
M. J. Bissell

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